Volume 7, Issue 2 (9-2008)
JRUMS 2008, 7(2): 131-136 |
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Ebadi A, Fakharzadh M, Najafi M, Beman Zaree A, Karimi Zarchi A, . Najafi Kalyani M, et al . The Frequency of Oxidative Stress Indexes after Endotracheal Suction in CABG Patients which Hospitalized in Jamaran Heart Hospital of Tehran. JRUMS. 2008; 7 (2) :131-136
URL: http://journal.rums.ac.ir/article-1-458-en.html
URL: http://journal.rums.ac.ir/article-1-458-en.html
A. Ebadi *, M. Fakharzadh, MS Najafi, A. Beman Zaree, AK. Karimi Zarchi, M. . Najafi Kalyani, Z. Farsi, H. Mahmoudi
Abstract: (12546 Views)
Background and Objectives: Some nursing and medicine activities may increase the production of free radicals in patients. Therefore, this study was performed to determine the effect of suction with a tube located inside of the trachea on the amount of oxidative stress indexes in CABG patients.
Matrial and Methods: This clinical study was performed on 35 patients which were under coroner vascular graft surgery. Blood samples were collected 3 times (before, immediatery and 15 minutes after suction) and then, the amounts of glutathione and the activity of glutathione peroxidase were measured.
Results: Results of this study showed that both glutathione and glutathione peroxidase activity are significantly decreased both in immediately and 15 minutes after suction comparing to before suction (p<0.001).
Conclusions: Suction is a free radical producing process which causes some changes in activities of anti-oxidants. The defect of anti- oxidants related defense of body causes oxidative stress. Therefore, further studies are needed to find out a way to overcom this problem.
Key words: Endotracheal Suction, Glutathione (GSH), Glutathione Peroxidas (GSH-P)
Funding: This research was funded by Baghiatallah Medical Sciences University.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Baghiatallah Medical Sciences University approved the study.
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