TY - JOUR T1 - Evaluation of the Antibacterial Effect of Methanol and Aqueous Extracts of Vaccinium Arctostaphylos Fruit against Salmonella spp in vitro TT - بررسی اثر ضد باکتریایی عصاره متانولی و آبی میوه گیاه Vaccinium arctostaphylos بر برخی از گونه‌های سالمونلا در شرایط آزمایشگاهی JF - RUMS_JOURNAL JO - RUMS_JOURNAL VL - 14 IS - 4 UR - http://journal.rums.ac.ir/article-1-2228-en.html Y1 - 2015 SP - 257 EP - 268 KW - Salmonella KW - Vaccinium arctostaphylos KW - Methanol extract KW - Aqueous extract KW - Inhibitory effect N2 - Background and Objective: Salmonella infections, or salmonellosis such as typhoid, bacteremia, enterocolitis are the major health problem worldwide, especially in developing countries including Iran. This study aimed to evaluate the antibacterial effect of methanol and aqueous extracts of Vaccinium arctostaphylos fruit against Salmonella spp. Materials and Methods: The present study is an experimental one Methanol and aqueous extracts of Vaccinium arctostaphylos fruit were prepared by maceration and Soxhlet method. Antimicrobial effects of the extracts were evaluated by agar diffusion method against Salmonella typhi (PTCC: 1609) and six clinical strains of Salmonella. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined by micro-dilution method. Results: All of the studied strains were sensitive to the aqueous and methanol extracts of Vaccinium arctostaphylos fruit. The mean zones of inhibition were obtained in ranging from 6.6 to 26.6 mm. Statistical analysis showed a significant difference between the mean diameters of inhibition zone and increased extracts concentrations (p   M3 ER -