Journal of Rafsanjan University of Medical Sciences
مجله دانشگاه علوم پزشکی رفسنجان
JRUMS
Medical Sciences
http://journal.rums.ac.ir
69
journal69
1735-3165
2008-7268
10.61186/jrums
fa
jalali
1393
9
1
gregorian
2014
12
1
13
6
online
1
fulltext
fa
بررسی آلودگی به کاندیدا آلبیکنس و عوامل مرتبط با آن در زنان مراجعهکننده به مراکز بهداشتی- درمانی شهر جیرفت در سال 1389: یک گزارش کوتاه
The Prevalence of Candida Albicans Infection and Related Factors in Women Referring to Health Centers of Jiroft in 2010: A Short Report
زنان
Gynecology
پژوهشي
Research
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 120% "><!--stripped--> gte vml 1]><v:roundrect id="_x0000_s1026" style='position:absolute
left:0text-align:leftmargin-left:2.45ptmargin-top:1.4ptwidth:449.5pt
height:374ptz-index:-1' arcsize="1475f">
<w:wrap anchorx="page"/>
</v:roundrect><!--stripped--><span style="position: absolute z-index: -1 left: 0px margin-left: 2px margin-top: 1px width: 602px height: 501px "><img alt="AWT IMAGE" width="602" height="501" src="file:///C:/DOCUME~1/ADMINI~1/LOCALS~1/Temp/msohtmlclip1/01/clip_image001.gif" v:shapes="_x0000_s1026" ></span><b><span lang="FA" style="font-size: 12pt line-height: 120% font-family: 'B Nazanin' ">چکیده<o:p /></span></b></p>
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 122% "><b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' ">زمینه
و هدف:</span></b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' ">
<span style="color: black ">کاندیدا آلبیکنس یکی از شایعترین علل واژینیت و از مهمترین
دلایل مراجعه زنان به مراکز بهداشتی درمانی میباشد. این مطالعه به منظور تعیین
آلودگی به کاندیدا آلبیکنس و عوامل مرتبط با آن در زنان شهر جیرفت انجام گرفت.<o:p /></span></span></p>
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 122% "><b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">مواد و روشها:</span></b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "> این مطالعه مقطعی در سال 1389 بر روی 350 نمونه
صورت گرفت. پس از گرفتن شرح حال بیماران، سوابی از ترشحات واژینال بیماران تهیه و بلافاصله
به محیط کشت نیکرسون (</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">Nickerson</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>) انتقال یافت. جهت تشخیص گونههای کاندیدا
آلبیکنس از روش لوله زایا و مورفولوژی ماکروسکوپی و میکروسکوپی استفاده شد. در تجزیه
و تحلیلهای تک متغیره برای متغیرهای کیفی از آزمونهای مجذور کای و دقیق فیشر و
برای متغیرهای کمی از آزمون </span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">t</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span> مستقل و </span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">Mann - Whitney</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>
استفاده شد. سپس از مدل رگرسیون لجستیک (</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">Logistic regression</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>) برای ارزیابی اثر تطبیق
داده شده متغیرها استفاده </span><span lang="FA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">گر</span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">دید.<o:p /></span></p>
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 122% "><b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">یافتهها:</span></b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "> میانگین و انحراف معیار سنی نمونههای مورد بررسی
12/8±33/32 سال و شیوع کاندیدا آلبیکنس 05/0±71/29% مشاهده شد. خروجی رگرسیون
لجستیک ارتباط مستقل و معنیداری بین میزان تحصیلات فرد (001/0</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">p<</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>)، میزان تحصیلات همسر
(035/0=</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">p</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>) و شغل همسر (012/0=</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">p</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>) و روش پیشگیری از
بارداری (001/0</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black ">p<</span><span dir="RTL"></span><span dir="RTL"></span><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "><span dir="RTL"></span><span dir="RTL"></span>) و کاندیدیازیس نشان داد.<o:p /></span></p>
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 122% "><b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">نتیجهگیری:</span></b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "> در این مطالعه شیوع کاندیدیازیس بر اساس کشت مثبت
کاندیدا در ترشحات واژن، بالا بود و در گروههایی از زنان با عوامل خطر خاص، بیشتر
بود. دانستن این عوامل خطر میتواند در تشخیص و درمان زنان مبتلا، کمککننده باشد.</span><span dir="LTR" style="line-height: 122% font-family: 'Times New Roman', serif color: black "><o:p /></span></p>
<p class="MsoNormal" dir="RTL" style="margin-top: 0cm margin-right: 7.1pt margin-left: 7.1pt margin-bottom: 0.0001pt text-align: justify line-height: 122% "><b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black ">واژههای کلیدی:</span></b><span lang="AR-SA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' color: black "> کاندیدیازیس، زنان، شیوع، واژینیت، جیرفت</span><span lang="FA" style="font-size: 12pt line-height: 122% font-family: 'B Nazanin' "><o:p /></span></p>
<p class="MsoNormal" dir="RTL" style="text-align: justify text-indent: 10.5pt line-height: 125% "><span lang="FA" style="font-size: 1pt line-height: 125% font-family: 'B Nazanin' color: black "><!--stripped--> <!--stripped--></span></p>
<p class="MsoNormal" dir="RTL" style="text-align: justify text-indent: 10.5pt line-height: 125% "><span lang="FA" style="font-size: 1pt line-height: 125% font-family: 'B Nazanin' color: black "><!--stripped--> <!--stripped--></span></p>
<p class="MsoNormal" dir="RTL" style="text-align: justify text-indent: 10.5pt line-height: 125% "><span lang="FA" style="font-size: 1pt line-height: 125% font-family: 'B Nazanin' color: black "><!--stripped--> <!--stripped--></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Background and
Objective:</span></b><span style="font-family: 'Times New Roman', serif color: black "> Candida Albicans is one of the most common causes of vaginitis
and an important cause of women’s visits to health centers. This study was
aimed to determine the prevalence of Candida Albicans infection in women of
Jiroft.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Materials and Methods:</span></b><span style="font-family: 'Times New Roman', serif color: black "> This cross- sectional study was carried out in 2010 on 350 women.
After taking the patient's history, swabs of patient's vaginal discharges were
prepared and moved to <em>Nickerson's</em><span class="st1"> medium </span>immediately.
For diagnosing Candida Albicans, <span class="st1">germ<b>-</b></span><em><span style="font-weight: normal ">tube</span></em><span class="st1"> tests</span> and
macroscopic and microscopic morphology were used. In the univariate analysis,
Chi-Square test, and Fisher<span class="st1">'s</span> exact test were used for
qualitative variables and independent t-test and Mann-Whitney for quantitative ones.
Then the logistic regression model was used to assess the adjusted effect of
the variables.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Results:</span></b><span style="font-family: 'Times New Roman', serif color: black "> The mean age was 32.33±8.12 years and the prevalence of Candida
Albicans was 29.71%±0.05. Logistic regression's model revealed independent and
significant association between individual's education<span> </span>(p<0.001), husband's education (p=0.035)
and husband's occupation (p=0.012), and method of contraception (p<0.001)
and candidiasis.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Conclusion:</span></b><span style="font-family: 'Times New Roman', serif color: black "> In this study, the prevalence of vaginal candidiasis based on
positive culture of Candida, was high and higher in the group of women with
certain risk factors. Knowing these risk factors may be helpful in the
diagnosis and treatment of patients.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Key words:</span></b><span style="font-family: 'Times New Roman', serif color: black "> Candidiasis, Women, Prevalence, Vaginitis, Jiroft<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-size: 2pt line-height: 150% font-family: 'Times New Roman', serif color: black "><!--stripped--> <!--stripped--></span></b></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Funding:</span></b><span style="font-family: 'Times New Roman', serif color: black "> This research was funded by Kerman University of Medical
Sciences.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Conflict of interest:</span></b><span style="font-family: 'Times New Roman', serif color: black "> None declared.<o:p /></span></p>
<p class="MsoNormal" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">Ethical approval:</span></b><span style="font-family: 'Times New Roman', serif color: black "> The Ethics Committee of Kerman University of Medical Sciences
approved the study.<o:p /></span></p>
<p class="MsoNormalCxSpMiddle" style="text-align: justify line-height: 150% vertical-align: top direction: ltr unicode-bidi: embed "><b><span style="font-size: 1pt line-height: 150% font-family: 'Times New Roman', serif color: black "><!--stripped--> <!--stripped--></span></b></p>
<p class="MsoNormal" style="text-align: justify line-height: 200% direction: ltr unicode-bidi: embed "><b><span style="font-family: 'Times New Roman', serif color: black ">How to cite this article:</span></b><span style="font-family: 'Times New Roman', serif color: black "> </span><span style="font-family: 'Times New Roman', serif color: black ">Nasiri M, Fayazi S, Jamshidifar F, Sheikh Zayeri R</span><span style="font-family: 'Times New Roman', serif color: black ">. The Prevalence of Candida
Albicans Infection and Related Factors in Women Referring to Health Centers of
Jiroft in 2010: A Short Report. <i>J RafsanjanUniv Med Sci </i></span><span style="font-family: 'Times New Roman', serif color: black ">2014 13(6): 569-76.</span><span style="font-family: 'Times New Roman', serif color: black "> [Farsi]<o:p /></span></p>
کاندیدیازیس, زنان, شیوع, واژینیت, جیرفت
Candidiasis, Women, Prevalence, Vaginitis, Jiroft
569
576
http://journal.rums.ac.ir/browse.php?a_code=A-10-1545-1&slc_lang=fa&sid=1
N.
Khanjani
نرگس
خانجانی
narges.khanjani@gmail.com
6900319475328460013463
6900319475328460013463
No
School of Public Health,Kerman University of Medical Sciences
دانشکده بهداشت، دانشگاه علوم پزشکی کرمان
M.
Zamanian
مریم
زمانیان
maryam_zamanian23@yahoo.com
6900319475328460013464
6900319475328460013464
No
School of Public Health,Kerman University of Medical Sciences
دانشکده بهداشت، دانشگاه علوم پزشکی کرمان
P.
Molazadeh
پروین
مولی زاده
pmka2005@yahoo.com
6900319475328460013465
6900319475328460013465
Yes
School of Public Health,Kerman University of Medical Sciences
دانشکده بهداشت، دانشگاه علوم پزشکی کرمان
M.
Sadeghi
مریم
صادقی
pmka2005@yahoo.com
6900319475328460013466
6900319475328460013466
No
School of Public Health,Kerman University of Medical Sciences
دانشکده بهداشت، دانشگاه علوم پزشکی کرمان