Journal of Rafsanjan University of Medical Sciences
مجله دانشگاه علوم پزشکی رفسنجان
JRUMS
Medical Sciences
http://journal.rums.ac.ir
69
journal69
1735-3165
2008-7268
10.66224/jrums
fa
jalali
1403
7
1
gregorian
2024
10
1
23
6
online
1
fulltext
fa
بررسی اثر مهاری گرههای لنفاوی گوسفندی و آنتیبیوتیکها بر کوتی باکتریوم اکنس، استافیلوکوکوس اورئوس و استافیلوکوکوس اپیدرمیدیس در شرایط آزمایشگاهی: یک گزارش کوتاه
Investigation of Inhibitory Effect of Sheep Lymph Nodes and Antibiotics on Cutibacterium Acnes, Staphylococcus Aureus, and Staphylococcus Epidermidis in the Laboratory Condition: A Short Report
ميكروبيولوژي
Microbiology
پژوهشي
Research
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="AR-SA" style="font-size:11.5pt"><span style="line-height:120%"><span style="font-family:"B Nazanin"">چکیده</span></span></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><a name="_Hlk113374001"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">زمینه و هدف:</span></span></span></b></a><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin""> هدف این مطالعه<b> </b>تعیین اثر گرههای لنفاوی گوسفندی وآنتیبیوتیکها بر باکتری عامل آکنه و باکتریهایی که همراه آن وجود دارند، میباشد.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">مواد و روشها: </span></span></span></b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">در این مطالعه آزمایشگاهی، 24 بیمار آکنهدار جهت جداسازی باکتری انتخاب شدند. همچنین، 24 ایزوله کلینیکی استافیلوکوکوساورئوس و استافیلوکوکوساپیدرمیدیس از نمونه زخم بیماران جدا شد. پس از کشت باکتریها، حساسیت آن­ها به آنتیبیوتیکهای رایج بررسی شد، دادهها به صورت درصد گزارش شدند.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">یافتهها: </span></span></span></b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">کوتیباکتریوماکنس و استافیلوکوکوس اورئوس نسبت به ونکومایسین به­صورت 100 درصد حساس بودند، همچنین کوتیباکتریومآکنس در گروههای تتراسایکلین و ایمیپنم در 95 درصد موارد و در گروههای کوتریموکسازول و پیپیراسیلین/تازوباکتام در 90 درصد موارد حساسیت نشان دادند. بیشترین حساسیت استافیلوکوکوس اپیدرمیدیس نسبت به پیپیراسیلین/تازوباکتام (5/62 درصد) و بیشترین مقاومت دارویی آن (67/91 درصد) مربوط به گروههای آزیترومایسین و اریترومایسین بود. </span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">نتیجهگیری: </span></span></span></b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">با توجه به افزایش مقاومت دارویی، پیشنهاد میشود در درمان آکنه از آنتیبیوتیکهایی با کمترین مقاومت دارویی مانند ونکومایسین و ایمیپنم استفاده شود.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">واژههای کلیدی: </span></span></span></b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">گره لنفاوی، آنتیبیوتیک، آکنه، استافیلوکوکوس اپیدرمیس، کوتی باکتریوم اکنس</span></span></span></span></span></span></span></span><br>
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" style="position:absolute; left:0; text-align:left; margin-left:20px; margin-top:3px; width:467.05pt; height:56pt; z-index:-251652608; v-text-anchor:top"> <w:wrap anchorx="margin"> </w:wrap></v:roundrect><b><span lang="FA" style="font-size:2.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin""></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:112%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">ارجاع:</span></span></span></b><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin""> بابائی ع، رضازاده زرندی ا، شبانیزاده ا، تقیپور ز، دهقانیسلطانی س، رمضانی م، خدایی اح، تقوی مم،</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">بررسی اثر مهاری گرههای لنفاوی گوسفندی و آنتیبیوتیکها بر کوتی باکتریوم اکنس، استافیلوکوکوس اورئوس و استافیلوکوکوس اپیدرمیدیس در شرایط آزمایشگاهی: یک گزارش کوتاه</span></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:112%"><span style="font-family:"B Nazanin"">. <i>مجله دانشگاه علوم پزشکی رفسنجان</i>، سال 1403، دوره 23 شماره 6، صفحات: 575-568.</span></span></span></span></span></span></span></span><br>
<pre style="text-align:justify">
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><a name="_Hlk114425361"><b><span style="font-size:9.0pt"><span style="line-height:125%">Background and Objectives:</span></span></b></a> <span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">The aim of this study </span></span><span style="font-size:9.0pt"><span style="line-height:125%">was</span></span><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%"> to investigate the effect of sheep lymph nodes and antibiotics on the bacterium that causes acne </span></span><span style="font-size:9.0pt"><span style="line-height:125%">and the bacteria that usually exist with it</span></span><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">.</span></span><span style="font-size:9.0pt"><span style="line-height:125%"></span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Materials and Methods: </span></span></b><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">In this laboratory study, 24 patients with acne (18 to 45 years old) were selected to isolate the bacteria.</span></span> <span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">Also, 24 clinical isolates of <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> were isolated from the wound samples of patients.</span></span> <span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">After culturing the bacteria</span></span><span style="font-size:9.0pt"><span style="line-height:125%">, their sensitivity to common antibiotics</span></span><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%"> was evaluated.</span></span><span style="font-size:9.0pt"><span style="line-height:125%"> Data were reported as percentage.</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Results: </span></span></b><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">The results showed that <i>Cutibacterium acnes</i> and <i>Staphylococcus aureus</i> were 100% sensitive to vancomycin.</span></span> <span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">Also, <a name="_Hlk167094839"><i>Cutibacterium acnes</i> </a>showed sensitivity in tetracycline and imipenem groups in 95% of cases and in cotrimoxazole and piperacillin/tazobactam groups in 90% of cases.</span></span> <span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">In addition, the highest sensitivity of <i>Staphylococcus epidermis</i> to piperacillin/tazobactam (62.5%) and the highest drug resistance (91.67%) were related to azithromycin and erythromycin groups.</span></span><b><span style="font-size:9.0pt"><span style="line-height:125%"></span></span></b></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Conclusion: </span></span></b><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">Due to the increase in drug resistance, it is suggested to use antibiotics with the least drug resistance such as vancomycin and imipenem in the treatment of acne.</span></span><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:125%"></span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Keywords:</span></span></b><span style="font-size:9.0pt"><span style="line-height:125%"> Lymph node, Antibiotic, Acne, <i>Staphylococcus aureus</i>, </span></span><i><span lang="EN" style="font-size:9.0pt"><span style="line-height:125%">Cutibacterium acnes</span></span></i><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:125%"></span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span style="font-size:3.0pt"><span style="line-height:125%"></span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Funding:</span></span></b><span style="font-size:9.0pt"><span style="line-height:125%"> This study was funded by Rafsanjan University of Medical Sciences.</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Conflict of interest:</span></span></b><span style="font-size:9.0pt"><span style="line-height:125%"> None declared.</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:125%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:125%">Ethical considerations:</span></span></b><span style="font-size:9.0pt"><span style="line-height:125%"> The Ethics Committee of Rafsanjan University of Medical Sciences approved the study (IR.RUMS.REC.1399.103).</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span style="font-size:9.0pt"><span style="line-height:120%"></span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:120%">Authors’ contributions</span></span></b><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">:</span></span></b><b><span style="font-size:9.0pt"><span style="line-height:120%"></span></span></b></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span><b><span style="font-size:9.0pt"><span style="line-height:120%">Conceptualization:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> <a name="_Hlk168655656">Mohammad Mohsen Taghavi</a>, Ebrahim Rezazadeh Zarandi</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span><b><span style="font-size:9.0pt"><span style="line-height:120%">Methodology:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> <a name="_Hlk168655860">Mohammad Mohsen Taghavi,</a> Ahmad Shabanizadeh</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span><b><span style="font-size:9.0pt"><span style="line-height:120%">Data collection:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Mahnaz Ramezani, Amir Hesam Khodaei</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span><b><span style="font-size:9.0pt"><span style="line-height:120%">Formal analysis:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Abdolreza Babaee, Samereh Dehghani-Soltani</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span></b><b><span style="font-size:9.0pt"><span style="line-height:120%">Supervision:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Mohammad Mohsen Taghavi,<b> </b>Zahra Taghipour</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span></b><b><span style="font-size:9.0pt"><span style="line-height:120%">Project administration:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Mohammad Mohsen Taghavi</span></span><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%"></span></span></b></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%">- </span></span></b><b><span style="font-size:9.0pt"><span style="line-height:120%">Writing - original draft:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Abdolreza Babaee, Ebrahim Rezazadeh Zarandi</span></span></span></span></span></span></span>
<span style="font-size:10pt"><span style="line-height:120%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman",serif"><b><span style="font-size:9.0pt"><span style="line-height:120%">- Writing - review & editing:</span></span></b><span style="font-size:9.0pt"><span style="line-height:120%"> Mohammad Mohsen Taghavi, Abdolreza Babaee</span></span><b><span dir="RTL" lang="FA" style="font-size:9.0pt"><span style="line-height:120%"></span></span></b></span></span></span></span></span>
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" style="position:absolute; left:0; text-align:left; margin-left:2px; margin-top:4px; width:496.3pt; height:46.5pt; z-index:-251656704; v-text-anchor:top"> <v:textbox><table width="100%"><tbody><tr><td><div><span style="font-size:10pt"><span style="line-height:107%"><span style="font-family:"Times New Roman",serif"><b><span style="line-height:107%">Citation:</span></b> <span style="font-size:9.0pt"><span style="line-height:107%">Babaee A, Rezazadeh Zarandi E, Shabanizadeh E, Taghipour Z, Dehghani-Soltani S, Ramezani M, Khodaei AH, Taghavi MM. Investigation of Inhibitory Effect of Sheep Lymph Nodes and Antibiotics on Cutibacterium Acnes, Staphylococcus Aureus, and Staphylococcus Epidermidis in the Laboratory Condition: A Short Report</span></span><span style="font-size:9.0pt"><span style="line-height:107%">. </span></span><i><span style="font-size:9.0pt"><span style="line-height:107%">J Rafsanjan</span></span></i><span style="font-size:9.0pt"><span style="line-height:107%"> <i>Univ Med Sci</i> 2024; 23 (6): 568-75. [Farsi]</span></span></span></span></span></div></td></tr></tbody></table> </v:textbox> <w:wrap anchorx="margin"> </w:wrap></v:roundrect><span style="font-size:9.0pt"><span style="line-height:140%"></span></span></span></span></span></span></span>
</pre>
گره لنفاوی, آنتیبیوتیک, آکنه, استافیلوکوکوس اپیدرمیس, کوتی باکتریوم اکنس
Lymph node, Antibiotic, Acne, Staphylococcus aureus, Cutibacterium acnes
568
575
http://journal.rums.ac.ir/browse.php?a_code=A-10-2876-5&slc_lang=fa&sid=1
Abdolreza
Babaee
عبدالرضا
بابائی
babaee.ab@gmail.com
6900319475328460058556
6900319475328460058556
No
Assistant Prof., Dept. of Anatomical Sciences, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
استادیار گروه آموزشی علوم تشریحی، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Ebrahim
Rezazadeh Zarandi
ابراهیم
رضازاده زرندی
erezazadehzarandi50@gmail.com
6900319475328460058557
6900319475328460058557
No
Assistant Professor, Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
استادیار ، مرکز تحقیقات ایمونولوژی بیماریهای عفونی، پژوهشکده علوم پایه پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Ahmad
Shabanizadeh
احمد
شبانی زاده
shabani54@yahoo.com
6900319475328460058558
6900319475328460058558
No
Associate Prof., Dept. of Anatomical Sciences, Immunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
دانشیار گروه آموزشی علوم تشریحی، مرکز تحقیقات ایمونولوژی بیماریهای عفونی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Zahra
Taghipour
زهرا
تقی پور
taghipourz@yahoo.com
6900319475328460058559
6900319475328460058559
No
Associate Prof., Dept. of Anatomical Sciences, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
دانشیار گروه آموزشی علوم تشریحی، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Samereh
Dehghani-Soltani
سامره
دهقانی سلطانی
samereh.dehghani@gmail.com
6900319475328460058560
6900319475328460058560
No
Assistant Prof., Dept. of Anatomical Sciences, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
استادیار گروه آموزشی علوم تشریحی، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Mahnaz
Ramezani
مهناز
رمضانی
rmahnaz751@gmail.com
6900319475328460058561
6900319475328460058561
No
Master of Microbiology, Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
کارشناس ارشد میکروب شناسی، مرکز تحقیقات ایمونولوژی بیماریهای عفونی، پژوهشکده علوم پایه پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Amirhesam
Khodaei
امیرحسام
خدایی
khodaeeamirhesam@gmail.com
6900319475328460058562
0009-0008-7571-7918
No
. Laboratory Sciences Student, Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
دانشجوی علوم آزمایشکاهی، مرکز تحقیقات ایمونولوژی بیماریهای عفونی، پژوهشکده علوم پایه پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران
Mohammad Mohsen
Taghavi
محمد محسن
تقوی
taghavi164@yahoo.com
6900319475328460058563
6900319475328460058563
Yes
Associate Prof., Dept. of Anatomical Sciences, Social Determinants of Health Research Center, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
دانشیار گروه آموزشی علوم تشریحی، مرکز تحقیقات عوامل اجتماعی مؤثر بر سلامت، دانشکده پزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران