Volume 16, Issue 5 (9-2017)
JRUMS 2017, 16(5): 409-420 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Hosseini M, Akbari gora F. Effect of Eight Weeks Intermittent Medium Intensity Training with Curcumin Intake on Serum Levels of ICAM-1 and VCAM-1 in Menopause Fat Rats. JRUMS 2017; 16 (5) :409-420
URL: http://journal.rums.ac.ir/article-1-3687-en.html
URL: http://journal.rums.ac.ir/article-1-3687-en.html
Islamic Azad univeTehrarsity east Tehran branch
Full-Text [PDF 245 kb]
(1764 Downloads)
| Abstract (HTML) (4467 Views)
Full-Text: (2835 Views)
Effect of Eight Weeks Intermittent Medium Intensity Training with Curcumin Intake on Serum Levels of ICAM-1 and VCAM-1 in Menopause Fat Rats
M. Hosseini[1], F. Akbari gora[2]
Received: 08/03/2017 Sent for Revision: 08/05/2017 Received Revised Manuscript: 02/07/2017 Accepted: 05/07/2017
Background and Objective: Plasma levels of adhesion molecule and lipid profile have emerged as an important indicator of risk for cardiovascular diseases. Exercise training can be effective in the improvement of the endothelial dysfunction. The purpose of this study was the effect of eight weeks intermittent medium intensity training with curcumin intake on serum levels of ICAM-1 and VCAM-1in menopause fat rats.
.Materials and Methods: In this experimental study 28 Wistar menopause fat rats aged 24months divided into four groups randomly: control supplement training and training + supplement (7 rats each group). Training program was planed for 8 weeks and 3 session per week each session consisted of 10 sets activity in one minute with intensity of 50% and 2 minutes rest between sets. In the first week subjects started with 14 meters per minute and increase their speed to 28 meters per minute till eight week. Blood samples were taken 48 hours after the last training session and measured the levels of ICAM-1،VCAM-1, triglyceride and total cholesterol. One-way analysis of variance and Pearson’s correlation coefficient were used.
Results: The results showed ICAM-1 levels decreased in experimental groups that in comparison with control group it was significant (p≤0.05). VCAM-1 levels decreased in experimental groups but was not significant (p>0.05) Between ICAM-1 and VCAM-1 levels was not significant correlation. Triglyceride and total cholesterol levels decreased in experimental groups but were not significant (p>0.05).
Conclusion: It is probably effective in preventing cardiac diseases with the implementation of medium intensity interval training and use of curcumin that decrease the cardiac risk factors.
Key words: Interval Training, ICAM-1, VCAM-1, Obesity, Rat
Funding: This study did not have funds.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Islamic Azad University East Tehran Branch
approved the study.
How to cite this article: Hosseini M, Akbari gora F. Effect of Eight Weeks Intermittent Medium Intensity Training with Curcumin Intake on Serum Levels of Icam-1 and Vcam-1 in Menopause Fat Rats. J Rafsanjan Univ Med Sci 2017; 16(5): 409-20. [Farsi]
[1]-Assistant Prof., Dept. of exercise physiology, Faculty of human sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran
(Corresponding author) Tell: (021) 88255382, Fax:(021) 66484077,E-mail mhbisadi@yahoo.com
M. Hosseini[1], F. Akbari gora[2]
Received: 08/03/2017 Sent for Revision: 08/05/2017 Received Revised Manuscript: 02/07/2017 Accepted: 05/07/2017
Background and Objective: Plasma levels of adhesion molecule and lipid profile have emerged as an important indicator of risk for cardiovascular diseases. Exercise training can be effective in the improvement of the endothelial dysfunction. The purpose of this study was the effect of eight weeks intermittent medium intensity training with curcumin intake on serum levels of ICAM-1 and VCAM-1in menopause fat rats.
.Materials and Methods: In this experimental study 28 Wistar menopause fat rats aged 24months divided into four groups randomly: control supplement training and training + supplement (7 rats each group). Training program was planed for 8 weeks and 3 session per week each session consisted of 10 sets activity in one minute with intensity of 50% and 2 minutes rest between sets. In the first week subjects started with 14 meters per minute and increase their speed to 28 meters per minute till eight week. Blood samples were taken 48 hours after the last training session and measured the levels of ICAM-1،VCAM-1, triglyceride and total cholesterol. One-way analysis of variance and Pearson’s correlation coefficient were used.
Results: The results showed ICAM-1 levels decreased in experimental groups that in comparison with control group it was significant (p≤0.05). VCAM-1 levels decreased in experimental groups but was not significant (p>0.05) Between ICAM-1 and VCAM-1 levels was not significant correlation. Triglyceride and total cholesterol levels decreased in experimental groups but were not significant (p>0.05).
Conclusion: It is probably effective in preventing cardiac diseases with the implementation of medium intensity interval training and use of curcumin that decrease the cardiac risk factors.
Key words: Interval Training, ICAM-1, VCAM-1, Obesity, Rat
Funding: This study did not have funds.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Islamic Azad University East Tehran Branch
approved the study.
How to cite this article: Hosseini M, Akbari gora F. Effect of Eight Weeks Intermittent Medium Intensity Training with Curcumin Intake on Serum Levels of Icam-1 and Vcam-1 in Menopause Fat Rats. J Rafsanjan Univ Med Sci 2017; 16(5): 409-20. [Farsi]
(Corresponding author) Tell: (021) 88255382, Fax:(021) 66484077,E-mail mhbisadi@yahoo.com
[2] - MSC in exercise physiology, Faculty of human sciences, East Tehran Branch, Islamic Azad University, Tehran, Iran
Type of Study: Research |
Subject:
تربيت بدني
Received: 2017/02/8 | Accepted: 2017/07/5 | Published: 2017/09/13
Received: 2017/02/8 | Accepted: 2017/07/5 | Published: 2017/09/13
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
