Toxoplasmosis and Its Current Status in Iran: A Narrative Review
A. Asghari[1], E. Ghasemi[2], A. Yousefi[3], H. Majidiani[4]
Received: 14/04/21 Sent for Revision: 23/05/21 Received Revised Manuscript: 13/11/21 Accepted: 16/11/21
Toxoplasmosis is one of the significant zoonoses, and about one-third of the world population possess anti-
Toxoplasma gondii antibody titers. From veterinary and public health perspective, the disease causes abortion in small ruminants and pregnant women, as well as brain complications in immunocompromised subjects. Although, a century has passed since the discovery of this interesting opportunistic protozoa, its pathogenic mechanisms and genotypes are still being explored. Current review deals with this opportunistic infection at a glance. There exists special interest in
Toxoplasma infection researches in last two decades, with especial emphasis on the seroepidemiology in at-risk populations, genotyping in various samples, anti-
Toxoplasma drug discovery, as well as vaccination approaches against toxoplasmosis. Current review highlights different aspects of
Toxoplasma infection and implies the potential gaps and research fields for further exploration.
Key words: Toxoplasma gondii, Toxoplasmosis, Iran
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical approval: Not applicable
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How to cite this article: Asghari A, Ghasemi E, Yousefi A, Majidiani H. Toxoplasmosis and Its Current Status in Iran: A Narrative Review.
J Rafsanjan Univ Med Sci 2022; 20 (11): 1253-78. [Farsi]
[1]- PhD Sudent in Medical Parasitology, Dept. of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, ORCID: 0000-0002-4005-2687
[2]- PhD in Medical Parasitology, Dept. of Medical Parasitology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran, ORCID: 0000-0002-3216-9201
[3]- PhD in Medical Parasitology, Students Research Center, Hamadan University of Medical Sciences, Hamadan, Iran, ORCID: 0000-0002-5648-8231
[4]- PhD in Medical Parasitology, Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran, ORCID: 0000-0001-5568-1366
(Corresponding Author) Tel (021) 88006544, Fax: (021) 88006544, E-mail: Hamidreza.majidiani@gmail.com