Volume 23, Issue 3 (7-2024)
JRUMS 2024, 23(3): 237-249 |
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Ethics code: IR.IAU.TNB.REC.1402.091
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Mohseni Z, Abedi B, Kazemzadeh Y. The Effect of High-Intensity Interval Training and Thyme Supplementation on the Serum Levels of Irisin and Nesfatin-1 in Sedentary Young Girls:
A Quasi-Experimental Study. JRUMS 2024; 23 (3) :237-249
URL: http://journal.rums.ac.ir/article-1-7334-en.html
URL: http://journal.rums.ac.ir/article-1-7334-en.html
North Tehran Branch, Islamic Azad University
Abstract: (312 Views)
Background and Objectives: Inactivity can reduce the serum level of some markers such as nesfatin-1 and irisin, which have positive effects on reducing inflammation and insulin resistance. Thyme is a plant whose extract has various properties, including anti-inflammatory effects. Therefore, the purpose of this research was to investigate the effect of eight weeks of high-intensity interval training (HIIT) along with thyme supplementation on the serum levels of irisin and nesfatin-1 in sedentary young girls
Materials and Methods: In this quasi-experimental study, 48 young girls were randomly divided into four groups of HIIT, thyme, HIIT+thyme, and control group. Thyme supplement was taken in the form of 20 mg soft capsules, half an hour before each meal. Serum levels of nesfatin-1 and irisin were analyzed using specific ELISA kits. Data were analyzed using ANOVA and paired t statistical tests with a significance level of 0.05.
Results: The serum level of irisin before the test (p=0.685) and after the test (p=0.556) was not significantly different among the studied groups. The post-test values of nesfatin-1 were significantly different among the groups (p<0.001). Intra-group evaluation showed that the changes of nesfatin-1 in the control and thyme groups were not significant (p>0.05). However, a significant increase in nesfatin-1 was observed in HIIT (p<0.001) and HIIT + thyme groups (p=0.001) after the interventions.
Conclusion: The increase of nesfatin-1 was one of the favorable effects of HIIT exercises with or without thyme consumption. Irisin levels were not affected by exercise or thyme supplementation.
Keywords: High-intensity interval training, Thyme, Irisin, Nesfatin-1, Sedentary
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical considerations: The Ethics Committee of Islamic Azad University of North Tehran branch approved the study (IR.IAU.TNB.REC.1402.091).
Authors’ Contributions:
- Conceptualization: Zahra Mohseni, Bahram Abedi, Yaser Kazemzadeh
- Methodology: Zahra Mohseni, Bahram Abedi
- Data collection: Zahra Mohseni
- Formal analysis: Bahram Abedi, Yaser Kazemzadeh
- Supervision: Bahram Abedi, Yaser Kazemzadeh
- Project administration: Bahram Abedi
- Writing - original draft: Zahra Mohseni
- Writing - review & editing: Zahra Mohseni, Bahram Abedi
Materials and Methods: In this quasi-experimental study, 48 young girls were randomly divided into four groups of HIIT, thyme, HIIT+thyme, and control group. Thyme supplement was taken in the form of 20 mg soft capsules, half an hour before each meal. Serum levels of nesfatin-1 and irisin were analyzed using specific ELISA kits. Data were analyzed using ANOVA and paired t statistical tests with a significance level of 0.05.
Results: The serum level of irisin before the test (p=0.685) and after the test (p=0.556) was not significantly different among the studied groups. The post-test values of nesfatin-1 were significantly different among the groups (p<0.001). Intra-group evaluation showed that the changes of nesfatin-1 in the control and thyme groups were not significant (p>0.05). However, a significant increase in nesfatin-1 was observed in HIIT (p<0.001) and HIIT + thyme groups (p=0.001) after the interventions.
Conclusion: The increase of nesfatin-1 was one of the favorable effects of HIIT exercises with or without thyme consumption. Irisin levels were not affected by exercise or thyme supplementation.
Keywords: High-intensity interval training, Thyme, Irisin, Nesfatin-1, Sedentary
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical considerations: The Ethics Committee of Islamic Azad University of North Tehran branch approved the study (IR.IAU.TNB.REC.1402.091).
Authors’ Contributions:
- Conceptualization: Zahra Mohseni, Bahram Abedi, Yaser Kazemzadeh
- Methodology: Zahra Mohseni, Bahram Abedi
- Data collection: Zahra Mohseni
- Formal analysis: Bahram Abedi, Yaser Kazemzadeh
- Supervision: Bahram Abedi, Yaser Kazemzadeh
- Project administration: Bahram Abedi
- Writing - original draft: Zahra Mohseni
- Writing - review & editing: Zahra Mohseni, Bahram Abedi
Type of Study: Research |
Subject:
تربيت بدني
Received: 2024/03/15 | Accepted: 2024/06/15 | Published: 2024/07/20
Received: 2024/03/15 | Accepted: 2024/06/15 | Published: 2024/07/20
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