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A. Mahmoodi Rad, M. Foroozi, S. Mohamad Alizaheh,
Volume 4, Issue 2 (6-2005)
Volume 4, Issue 2 (6-2005)
Abstract
Changes of Intracranial Pressure Due to Some Curative and Hygienic Activities
A. Mahmoodi Rad MSc1, M. Foroozi MSc2*, S. Mohamad alizaheh MSc3
1- Academic Member, School of Nursing, Lar, Iran
2- Academic Member, School of Nursing and Midwifery, Kerman, Iran
3- Academic Member, School of Nursing and Midwifery, Kerman, Iran
Background: Evaluation the patients for determining the sings of increasing intracranial pressure (ICP) is one of the most important nursing activities. One of the problems in caring the patients with neurological disorders is finding the intracranial pressure and prevention of its secondary complications.
The aim of this descriptive comparative survey was to evaluate the alterations of intracranial pressure due to some curative and health activities in patients admmitted to intensive care unit of Shiraz Namazee hospital.
Materials and Methods: In this study the effects of 18 health care activities with 1620 repeats were evaluate in 6 patients with increased ICP due to head injuries .
A researcher- made check list was used for data collection after determining proper reliability and validity. Central and descriptive tendency, Spearman coefficient and Wilcoxon tests were used for data analysis.
Results: The results of this survey showed that from 18 activities that showed significant difference in ICP, dressing change of catheter site. had highest pressure differential mean (9.62) and activity of pupil reaction of left eye to light had lowest pressure differential mean (1.40) respectively. The results also showed that among 1620 repeated activities only three were associated with decreased ICP.
The result showed that, dressing change of catheter insertion site and inserting angiochat had lowest and highest correlation coefficients 0.17 and 0.8 respectively.
Conclusion: Although arising ICP has seen after implementation of 18 health care activities but the raise was transient and reconvert in less than one minute.
Key words: Intracranial pressure, Curative and hygienic activities
* Corresponding author:Tel: (0341)3220796 , Fax:(0341)3220765, E-mail: forozy@yahoo.com
Journal of Rafsanjan University of Medical Sciences and Health Services, 2005, 4(2): 111-121
H. Mozdarani, Sh. Zarei Moradi,
Volume 4, Issue 4 (12-2005)
Volume 4, Issue 4 (12-2005)
Abstract
Effect of Vitrification on Survival and Chromosomal Abnormalities of Frozen- Thawed 8-Cell Mouse Embryos
�
H. Mozdarani PhD [1] , Sh. Zarei Moradi MSc [2]
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Background and Objective : Cryopreservation of supernumerary human embryos derived from assisted reproduction technology (ART) procedures has provided patients the option of storage of gametes and embryos for future treatment. However, because of technical problems embryo freezing is not a routine procedure in all ART centers. This study was designed to compare the post-thaw survival and chromosomal aberrations caused by vitrification on vitrified 8-cell mouse embryos by control group.
Materials and Methods : In this exprimental study using flashing method eight-cell mouse embryos were obtained from NMRI mouse 3 days after mating. Retrieved embryos were transferred in to vitrification solution containing ethylene glycol as cryoprotectant, then transferred into a vitrification straw using standard technique, and vitrified in liquid Nitrogen. Four groups of embryos including controls according to the time of vitrification, from 24 hours to 1 month were frozen. After appropriate freezing time embryos were thawed and studied for their viability and chromosomal abnormalities after thawing.
Results: Viability of frozen embryos reduced from 98.2% to 79.2% after 1 month vitrification. Furthermore, chromosomal aberrations significantly increased with increasing freezing time (p<0.01).
Conclusion: This study indicates that freezing affects viability of embryos and chromosome structure compared to the control group. Effects of vitrification might produce chromosomal alterations leading to cell death. These alterations might probably be due to cytoskeleton, spindle or other cellular organelle damages.
Key words: Mouse preimplantation embryo, Vitrification , Survival, Chromosomal abnormality
[1] - Professor, Dept of Medical Genetics, School of Medical Sciences, Tarbiat Modarres University, Tehran
�(Corresponding author) Tel: (021)88011001, Fax: (021) 88006544, E.mail: mozdarah@modares.ac.ir
[2] - Academic Member, Dept. of Medical Genetics, Genetic Center Azad University, Royan Institute, Tehran
M. Mobasher, H. Sahraei, B. Sadeghi-Rad, M. Kamalinejad, J. Shams,
Volume 5, Issue 3 (12-2006)
Volume 5, Issue 3 (12-2006)
Abstract
The Effects of Crocus sativus Extract on the Acquisition and Expression of Morphine-Induced Conditioned Place Preference in Mice M. Mobasher GP , H. Sahraei PhD , B. Sadeghi-Rad , M. Kamalinejad MSc , J. Shams MSc Received: 13/08/05 Sending for Revision: 16/01/06 Receiving Revised Manuscript: 25/09/06 Accepted: 03/10/06 Background and Objective : The effects of Crocus sativus (Saffron) on the euphoric properties of morphine have not yet been studied. In the present study, the effects of water extract of C. sativus stigma on the acquisition and expression of morphine-induced Conditioned Place Preference (CPP) in male N-MARI mice (weighted 20-25 g) were investigated. Materials and Methods: This experimental study was conducted on 136 male mice that were divided into 17 groups (n=8/group). In a pilot study, different doses of morphine (1, 2, 4 and 8 mg/kg) and C. sativus extract (10, 50 and 100 mg/kg) were injected to the animals, to evaluate the drugs ability in induction of place preference. In the second phase of the experiments, the extract of the C. sativus was administered during or after induction of morphine CPP. Then, CPP were tested in the animals. One-way analysis of variance (ANOVA) was performed for statistical procedure. Results: Administration of morphine (1, 2, 4 and 8 mg/kg), increased the required time in the compartment paired with morphine (i.e. CPP) that was significant (p<0.001) for those animals that received 4 and 8 mg/kg of morphine. Administration of the plant extract (50 mg/kg) also produced a significant CPP (p<0.01) compared with control group. Injection of the same dose of the extract before morphine (8 mg/kg) administration, caused a decrease in the time spent in drug-paired side only in dose of 100 mg/kg of the extract (p<0.05). In addition, injection of the plant extract in the test days to the animals, which reveived morphine (8 mg/kg) in the conditioning days, enhanced the expression of morphine CPP in the animals, that was statisticaly significant for the extract at the concentration of 50 mg/kg (p<0.05). Conclusion: It could be concluded that injection of the extract of C. sativus can inhibit the acquisition but enhanced the expression of morphine-induced CPP. In addition, the extract can produce CPP by itself. Key words: Morphine, Conditioned Place Preference, Mice, Saffron Extract
M. Safavi, A. Honarmand, S. Abbasi, D. Moradi,
Volume 8, Issue 2 (6-2009)
Volume 8, Issue 2 (6-2009)
Abstract
The Effect of Adding Ketamine to The Drugs for Induction of Anesthesia on the Cardiovascular Response to the Endotracheal Intubation
�
M. Safavi [1] , A. Honarmand [2] , S. Abbasi2 , D. Moradi [3]
�
Received: 06/01/08 Sent for Revision: 14/09/08 Received Revised Manuscript: 18/01/09 Accepted: 31/01/09
�
Background and Objectives: This investigation was performed to examine hemodynamic stability for the period of anesthesia induction and intubation, employing thiopental added to fentanyl, thiopental added to ketamine, and thiopental added to fentanyl and ketamineMaterials and Methods: Sixty�adult patients were randomly allocated in this randomized clinical trial to one of the three groups according to the drugs used for the induction: thiopental (4 mg/kg) plus to fentanyl (3µg/kg) (TF, n=20), thiopantal plus ketamine (0.1mg/kg) (TK, n=20), or fentanyl (3µg/kg) and ketamine (0.1mg/kg) (TFK, n=20). Hemodynamic responses were evaluated by determining changes in blood pressure (BP) and heart rate (HR) just before laryngoscopy and at 1, 3, 5, and 10 min after that.
Results: Throughout the induction of anesthesia BP and HR variations were more in the TK group than that in the TF and TFK groups (p = 0.009). After laryngoscopy, BP significantly increased in the TF and TK groups compared with the TFK group (p=0.027), the rank sequence was TK > TF > TFK. Heart rate was also significantly increased in TK group compared with TF and TFK groups after laryngoscopy (p= 0.013), the rank sequence was TK > TF > TFK. After intubation, BP and HR remained unchanged compared with their preintubation levels in the TFK group.
Conclusion: Thiopental added to fentanyl and ketamine caused greater reduction of instabilities in hemodynamic variables throughout the induction of anesthesia and tracheal intubation than thiopental added to fentanyl or thiopental added to ketamine.
Key words: Cardiovascular Parameters , Thiopental, Fentanyl, Ketamine, Tracheal Intubation
�
Funding: This research was funded by Isfahan University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Isfahan University of Medical Sciences approved the study.
[1] - Assistant Prof., Dept. of Anesthesia and Intensive Care, Department of Anesthesiology and Intensive Care Medicine, University of Medical Sciences, Isfahan, Iran.
(Corresponding Author) Tel: (0311) 6270292, Fax: (0311) 6684510, E-mail: safavi@med.mui.ac.ir
[2] - Assistant Prof., of Anesthesia and Intensive Care, Department of Anesthesiology and Intensive Care, Isfahan University of Medical Sciences, Isfahan, Iran
[3] - Dept. of Anesthesiology and Intensive Care, University of Medical Sciences, Isfahan, Iran
Gh. Saki, K. Radan, Sh. Mostafa Radmard, I. Rashidi ,
Volume 9, Issue 3 (9-2010)
Volume 9, Issue 3 (9-2010)
Abstract
The Effect of Unilateral Testicular Blunt Trauma on Number and Motility of Sperms in Contra Lateral Testis of Wistar Rat
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Gh. Saki [1] , K. Radan [2] , Sh. Mostafa Radmard2, I. Rashidi [3]
�
Received: 27/10/09 Sent for Revision: 16/02/10 Received Revised Manuscript: 13/06/10 Accepted: 20/06/10
�
Background and Objectives: There are conflicting reports about the effects of blunt trauma on fertility. This study was designed to evaluate the effect of unilateral blunt testicular trauma on sperm parameter of contalateral testis and the protective effect of zinc on possible damage.
Materials and Methods: This experimental study was conducted in the cell culture laboratory, Department of Anatomy of Ahvaz Jundishapur University of Medical Sciences, in 2006. T hirty prepubertal male wistar rats were divided randomly into three equal groups. Group1 was used as control. Rats in group II and group III, as blunt testicular trauma groups, were subjected to left blunt testicular trauma. After the trauma, animals in group III were given 30 mg/kg zinc sulfate intraperitoneally and this treatment was continued for 40 days at a dose of 500 ppm per day orally. All the right epididymis of rats were removed and the number and motility of sperms were examined using Makler chamber and inverted microscope.
Results: The number of sperms in group II was significantly decreased compared to the other two groups (p<0.05). Our results showed that groups II and III have significantly lower sperm motility in comparisons with group I (p<0.05). However there was not any significant differences in sperm mobility between group II and III.
Conclusion: These results suggested that unilateral blunt testis trauma has a negative effect on sperm count and progressive motility of sperm. Zinc has a protective effect on sperms' count, but has no protective effect on motility of sperms.
Key words: Trauma, Sperm count, Sperm Motility, Zinc, Rat
�
Funding : This research was funded by Ahvaz Jundishapur University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval : The Ethics Committee of Ahvaz Jundishapur University of Medical Sciences approved the study.
[1] - Associate Prof., Physiology Research Center, Jundishapur University of Medical Sciences, Ahvaz , Iran
(Corresponding Author) Tel: (0611 ) 3330074, Fax: (0611) 3332036, E-mail: ghasemsaki@yahoo.com .
[2] - Assistant Prof., Dept. of Urology , Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
[3] - Associate Prof., Dept. of Pathology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
R. Moradzadeh, J. Hasanzadeh, A.r. Rajaaeifard, S. Tahmasebi, P. Golmohammadi,
Volume 10, Issue 4 (12-2011)
Volume 10, Issue 4 (12-2011)
Abstract
Background and Objectives: The role of gene-environment interaction in epidemiology has been widely considered. The traditional methods of studying the gene-environment interaction need appropriate control groups which their selection may be associated with some problems. Therefore, new methods have been created to study these interactions from which are the case-only designs. In this method, only the cases data are being used. In this study, gene-environment interaction in patients with breast cancer was investigated using the case-only and case-control designs .
Material and Methods: This study conducted in 2008, using two methods: matched case-control and case-only. Simple random sampling was used to select 300 patients with breast cancer in Shahid Mottahari Clinic for two aforementhioned designs. The control group for the matched case-control study was selected from the women referring to Shahid Mottahari Clinic. Data were analysed using lagistic regressian and conditional logistic regression.
Results: The confidence intervals and log likelihood in all variables in case-only design was better than the matched case-control. In case-only design, the standard error in the following variables age at menarche, the first delivery at the age of ≥34 yrs and /or nulliparity, the number of live births, use of oral contraception pills, and breastfeeding history were less than those in the matched case-control design. In case-only design, the P-value of the above-menthined variables was less than those of the matched case-control design.
Conclusion: The case-only design is an efficiency method for investigating of the interaction in terms of statistical study, sample size and the easily implementing.
Key words: Case-only, Case-control, Breast cancer, Gene-Environment Interaction
Funding: This research was funded by Shiraz University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Shiraz University of Medical Sciences approved the study.
How to cite this article : Moradzadeh R, Hasanzadeh J, Rajaaeifard A.R, Tahmasebi S, Golmohammadi P. Investigation on Gene-Environment Interaction using Breast Cancer Data a Case-Only and Case-control Designs. J Rafsanjan Univ Med Sci 2012 10(4): 267-78. [Farsi]
A. Salari Sharif, M. Sattari, M. Moradi, R. Shahrokhabad,
Volume 11, Issue 2 (6-2012)
Volume 11, Issue 2 (6-2012)
Abstract
Background and Objectives : Staphylococcus aureus is the positive gram coccus which is able to cause different kinds of infection in certain condition. The function of this bacteria is to provide the conditions for the invasion of it to the host with the secretion of different sorts of toxins such as entrotoxin. A and B entrotoxins have the most infections effect among these toxins. that’s why, this experiment for the has been conducted for the detection of entrotoxin genes A and B in clinical samples.
Materials and Method: This cross-sectional and descriptive study, which was conducted from September 2007 to August 2008. Two handred and forty clinical samples from wound, wound, blood, ear, nose, vomited secretions and urine were separation investigated (forty from each sample) and taken from the patients. then after the culture of the samples and conducting confirming biochemical tests, then they were assessed by Poly Chain Reaction technique.
Results: After the diagnosis of this bacteria and conducting objective test, from two hundred and forty samples examined throughout this study, fifty ones (20.83%) were infected by Staphylococcus aureus. Thirty seven cases (74%) of these infected samples were carrying both entrotoxin A and B genes. The frequencies of A and B genes were 11(22%) and 2 (4%), respectively.
Discussion: This study identified that 20.83% of the patients were carrying the pathogen as the source of infection. The detection of entrotoxin A and B genes, shows the most important role they have in bringing about superinfection.
Key words: Staphylococcus Aureus, Gene, Enterotoxins, PCR
Funding: This research was funded by Islamic Azad University Qom Branch.
Conflict of Interest: Not declared.
Ethical approval: The Ethics Committee of Islamic Azad University Qom Branch approved the study.
How to cite this article : Salari Sharif A, Sattari M, Moradi M, Shahrokhabad R . Detection of Staphylococcus aureus Entrotoxin Genes A & B in Clinical Samples of the Patients Referring to the Medical Centers of Kerman and Rafsanjan Cities by PCR Technique . J Rafsanjan Univ Med Scie 2012 11(2): 128-36. [Farsi]
R. Zareshahi, A.a. Haghdoost, A. Asadipour, B. Sadeghirad,
Volume 11, Issue 6 (12-2012)
Volume 11, Issue 6 (12-2012)
Abstract
Background and Objectives: Improving the drug usage pattern and moving through a community with appropriate, safe, with doses that meet individual requirements and for an adequate period of time is pivotal and recommended by World Health Organization. In this study, we investigate the drug prescription patterns in the Kerman province in Iran.
Materials and Methods: Prescription indices in Kerman prescription database of Food and Drug deputy in 2008, which includes prescription of 245 general practitioners and 455 physicians, were extracted. Selected WHO drug use indicators including number of prescribed medicines and their cost, maximum number of prescribed medicine, number of prescribed antibiotics, injection and corticosteroids were investigated in this cross-sectional study design.
Results: Average number of medicines prescribed per patient was 3.15±0.49 and 2.85±0.61 for general practitioners and physicians, respectively (p=0.001). Mean for maximum number of prescribed medicines were 6.67±1.20 and 6.57±1.67 for general practitioners and physicians, respectively. For general practitioners, 16.8% of prescriptions encountered with an injection, 17.7% encountered with a corticosteroid prescription and 51.9% encountered with an antibiotic. For physicians, 12.8% of prescriptions encountered with an injection, 15.4% with a corticosteroid prescription and 39.0% encountered with an antibiotic. The difference in prescribing these categories was significant between practitioners and physicians (p=0.001, p=0.001 and p=0.016, respectively). Experienced practitioners were more cautious in the number of prescribed medicines (p=0.001), however, the price of their prescriptions were higher than the young practitioners (p=0.001).
Conclusion: Despite the educational programs for the rational use of drugs, prescribing indicators are far from international recommended criteria. Hence, it is necessary to promote prescribing practices through establishing more comprehensive training courses related to the rational use of medicines. Besides, exerting surveillance systems is a useful way to monitor and control drug usage in the community.
Key words: Rational use of drug, Prescribing practice, General practitioner, Physician
Funding: This research was funded by Kerman University of Medical Sciences.
Conflict of interest: None declared.
Ethical Approval: The Ethics committee of Kerman University of Medical Sciences approved the study.
How to cite this article: Zareshahi R, Haghdoost AA, Asadipour A, Sadeghirad B. Rational Usage of Drug Indices in the Prescriptions of Kerman Medical Practitioners in 2008. J Rafsanjan Univ Med Scie 2012 11(6): 523-36. [Farsi]
M. Soodejani, R. Shirani Faradonbeh, S.a. Hashemi, A. Zahedi, A. Dehghani,
Volume 13, Issue 9 (2-2015)
Volume 13, Issue 9 (2-2015)
Abstract
Background and
Objective: Accidents
and traffic events are the most
influential factors in health. Given
the importance of this matter, we
designed this study to
investigate accidents and
analyze the data.
Materials and Methods: This
is a cross-sectional study. Data were collected via
recorded inputs in the accident registries in Health Network in 2012 and
analyzed using descriptive statistics.
Results:
In 2012, a total of 913 events were registered which 614 cases (67.3%) were
male and the rest of them (32.7 %)were female. Most of events were related to
accidents and traffic events (41%), poisoning (18%) and fall (10.1%)
respectively, and a total of 55.2% of the accidents had been occurred among
persons with the age of 15 to 35.
Conclusion
Since, half of the events occurred in the age groups of young and productive
population, it should be considered to train them accurately.
Key
words: Epidemiology, Accidents and injuries
Funding: This research was funded by Yazd University of Medical
Sciences
Conflict of
interest: None declared.
Ethical approval:
The Ethics Committee of Yazd University of Medical Sciences approved the study.
How to cite this article:
Soodejani M, Shirani Faradonbeh R, Hashemi SA, Zahedi A, Dehghani A.
Epidemiology of Accidents and Injuries in the City of Lordegan in 2012. J RafsanjanUniv Med Sci 2014 13(10): 917-22. [Farsi]
M.a. Zazouli, Y. Mahdavi, M. Moradi Golrokhi, D. Balarak,
Volume 13, Issue 11 (3-2015)
Volume 13, Issue 11 (3-2015)
Abstract
Background and Objective: Contamination
of swimming pools’ water can lead to the transfer of different diseases
to humans. The aim
of this study was to investigate the water quality health indicators in Urmia
swimming pools.
Materials and Methods: In this cross-sectional study, 14 active covered swimming
pools in Urmia city were chosen as census. The physical parameters
such as pH, temperature, turbidity and chemical ones such as residual chlorine,
hardness, alkalinity and microbial parameters such as heterotrophic bacteria,
Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus and fecal and
total coliforms were studied. Sampling has been
conducted every weak for 6 months and
they were analyzed under standard procedures. Data were analyzed using descriptive statistics.
Results: In this research, free residual
chlorine in %67, turbidity in %89.9, amount of pH in %83.8 and temperature in
%76.2 of the samples were desirable. In none of the pools, fecal coliform,
fecal streptococcus and staphylococcus aureus were
above the threshold levels. The populations of heterotrophic bacteria,
Staphylococcus aureus, and Pseudomonas aeruginosa in %69.96, %98.8, %85.1 of
the samples were desirable, respectively. Statistical analysis indicated that
there is a direct relationship between water turbidity and the population of
bacteria and reverse relationship between the residual chlorine and the studied organisms(r=-0.595, p<0.005)
Conclusion: According to the results,
complete compliance of the pools to the standards was fairly poor. It is also
important to maintain the proper level of free residual chlorine and pH in the
swimming pools to ensure safety of the water quality.
Key words: Swimming pool water, Microbial
quality, Physical quality, Chemical quality
Funding: This research
was funded by Mazandaran University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Mazandaran University of Medical Sciences approved
the study.
How to cite this
article: Zazouli
MA, Mahdavi Y,
Moradi Golrokhi M, Balarak D. Investigation of Water Quality Health Indicators of
the Swimming Pools in Urmia in 2013. J
RafsanjanUniv Med Sci 2015 13(11): 1033-48. [Farsi]
V. Vosoughi, F. Moradi, H. Aghaalinejad, M. Peeri,
Volume 14, Issue 2 (5-2015)
Volume 14, Issue 2 (5-2015)
Abstract
Background
and Objective: Protective
role of regular physical exercise against chronic metabolic and
cardio-respiratory diseases has been attributed to its anti-inflammatory
effects. Effect of strength training on adolescents’ inflammatory markers has
less been studied. The purpose of this study was to survey the effect of
strength training on CRP, TNF-α,
muscular strength, and cardio -respiratory function in inactive adolescent
girls.
Materials and Methods:
In a randomized controlled trial, twenty four inactive adolescent girls were
randomly assigned to two training (n=12) and control (n=12) groups. General
characteristics of subjects and serum levels of inflammatory markers C-Reactive
Protein (CRP) and Tumor Necrosis Factor-alpha (TNF-α) were assessed
before and after fourth and eighth weeks of training period. Strength training
protocol was included eight weeks weight training. Data were analyzed by two-way
repeated measures ANOVA test.
Results: The ANOVA test was
not statistically significant for body weight (p=0.089), body mass index (p=0.093),
body fat percent (p=0.142), and serum concentrations of CRP (p=0.154) and TNF-α (p=0.287) and the values of
these variables did not change after the training. Within-subject,
between-subject, and interaction effects for chest press (p=0.047, p=0.023, p=0.016,
respectively), semi-squat (p=0.011, p=0.037, p=0.049, respectively), and
maximal oxygen uptake (p=0.030, p=0.031, p=0.042, respectively) were
statistically significant and the values of these variables were increased at
the end of the fourth week, and more, eighth week of training period.
Conclusion: Circulating levels of inflammatory markers didn’t change following strength training (four- and eight-week) in inactive adolescent girls probably due to lack of impact on body weight and body fat percent. However, the implementation of strength training to improve muscle strength and cardio-respiratory function is recommended for these patients.
Key words: Strength training,
CRP, TNF-α,
Girls, Adolescent, Inactive
Funding: This research was funded by both
Islamic Azad University-Central Tehran Branch and corresponding author.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Islamic
Azad University-Baneh Branch approved the study.
How to cite this article: Vosoughi V, Moradi F, Aghaalinejad H, Peeri M. Effect of Strength Training on CRP, TNF-α,
Muscular Strength, and Cardio-Respiratory
Function in Inactive Adolescent Girls. J RafsanjanUniv Med Sci 2014 14(2):
85-98. [Farsi]
M. Malakootian, A. Dehdari Rad,
Volume 14, Issue 10 (1-2016)
Volume 14, Issue 10 (1-2016)
Abstract
Background and Objective: Acid dyes are synthetic organic compounds with complicated chemical structures which their treatment are difficult and costly. Discharchig of these dyes into the environmen causes harmful effects on ecosystem and water quality. In this study efficiency investigation of photo-fenton process in removal of acid green 20 dye from wastewater of textile industries was assessed.
Materials and Methods: Experimental study in the first half of 2015 was carried out in environmental health engineering research center, Kerman University of Medical Sciences. Factors which influence on removal including: pH, concentrations of H2O2 and Fe2+ ,light intensity of UV, the initial concentration of acid green 20 dye and contact time were investigated. Examinations under optimum removal conditions on real textile wastewater which its quality predetermined were also carried out. Sampling and examinations were conducted according to standard methods for examination of water and wastewater 20th edition. Descriptive statistics was used for analysis of data.
Results: Optimum removal conditions were pH = 3 [H2O2]= 0.2 mMol,[ Fe2+]=40 mg/L, UV=30 watt , the initial concentration of acid green 20 dye= 25 mg/L and time= 10 minutes. Maximum removal values were 94.62 and 73 percent for synthetic solutions and real wastewater, respectively.
Conclusion: Photo-Fenton process is an effective way in removal of acid dyes and able to remove these dyes from wastewater with high efficiency.
Key words: Photo-fenton efficiency, Textile wastewater, Acid green 20
Funding: This research was funded by Kerman University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Kerman University of Medical Sciences approved the study.
How to cite this article: Malakootian M, Dehdari rad A. Performance Evaluation of Photo-Fenton Process in Removal of Acid Green 20 Dye from Wastewater of Textile Industries. J RafsanjanUniv Med Sci 2016 14(10): 827-40. [Farsi]
J. Mohammadi, F. Safari, P. Rad, H. Delaviz,
Volume 14, Issue 11 (2-2016)
Volume 14, Issue 11 (2-2016)
Abstract
Background and Objectives: One of the side effects of chemotherapy is infertility and the use of Nasturtium Officinalis causes the anticancer molecules to be increased. This study was conducted to determine the effect of hydroalcoholic extract of Nasturtium Officinalis on ovarian changes after toxicity by doxorubicin in rats.
Materials and Methods: In this experimental study, thirty-six mature, female Wistar rats were randomized into six equal groups including groups, 1, 2, and 3 which received distilled water, 25 and 75 mg/kg of hydroalcoholic extracts of Nasturtium officinale daily for 21 days, respectively. Group 4 received only one single injection of doxorubicin 10 mg/kg (IP) and groups 5 and 6 received doxorubicin and 25 and 75 mg/kg of the extracts daily for 21 days, respectively. The Luteinizing hormone (LH) and follicle-stimulating hormone (FSH), estrogen, progesterone and ovarian histological changes and the ovaries weights were assessed at the end of the study. Data were analyzed using one-way ANOVA followed by Tukey's multiple comparisons test.
Results: The mean (mean ± SD) of FSH in the second and third groups were 0.21±0.05 and 0.23±0.01 respectively, that significantly increased compared to the fourth group 0.11±0.01 (p<0.05). The mean of primary follicle in the fifth and sixth groups were 4.32±1.31 and 5.41±1.43, respectively, that didn't show a significant increase compared to the fourth group 3.01±1.12, (p>0.05). The mean of graafian follicles in the fifth and sixth groups signifantly increased compared to the fourth group (p<0.05).
Conclusion: The hydroalcoholic extract of Nasturtium Officinalis with antioxidant properties have efficacy on ovarian follicle to improve oogenesis following toxicity by doxorubicin in rats.
Key words: Nasturtium officinalis, Doxorubicin, Ovary, Follicle, Hormone, Rat
Funding: This research was funded by Yasuj University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Yasuj University of Medical Sciences approved the study.
How to cite this article: Mohammadi J, Safari F, Rad P, Delaviz H. The Effect of Hydroalcoholic Extract of Nasturtium Officinalis on Ovarian Hormonal and Histological Changes after Toxicity by Doxorubicin in Rats. J RafsanjanUniv Med Sci 2016; 14(11): 953-64. [Farsi]
A. Moradi, H. Sajjadi, S.h. Mohaqeqikamal, M. Vameqi, S. Hosseini Teshnizi, Q.r. Qaedamini ,
Volume 14, Issue 11 (2-2016)
Volume 14, Issue 11 (2-2016)
Abstract
Background and objectives: Every individual's health is the basic foundation for the community health, and public health is considered as one of the important indicators of development. Considering the fact that children's health is one of the key priorities in all countries and today social health is one of the important issues raised in addressing the issue of health. this study is designed to investigate the labour children's social health referring to NGO (Non-Govermental Organization) centers in support of children's rights in Tehran.
Materials and Methods: In this descriptive cross-sectional study105 children between 13 to 18 years old referring to the promotion of quality of life centers of Iranian (Ilya),NaserKhosrow's house of children's support, Shoush house of children's support, Molavi's children support center, and the house of Elm in the city of Tehran in 2014 Were selected by census method. In order to evaluate social health, Kyes questionnaire and for demographic information a checklist was used. Data was analyzed using descriptive statistics, Pearson correlation coefficient and independent sample t-test.
Results: The results showed that social health of children with the mean of 54.44 ±10.86 was in an average level. The minimum and maximum scores obtained for social participation and social acceptance, respectivly. There was a significant relationship between the social health and the variables of nationality (p<0.001), educational status (p<0.001) and income (p=0.032),but there was no significant relationship between the social health and the variables of sex (p=0.104), accommodation (p=0.208) and age (p=0.230).
Conclusion: the results of this study revealed that social health of labour children is not desirable. Therefore, the promotion of public health and Identification and elimination of factors affecting labour children requires a common effort between all levels of society such as individuals, communities and government.
Key words: Social health, Labour children, Non-Govermental Organization, Children’s right
Funding; This study did not have any funds
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Researches University of Social Welfare and Rehabilitation Sciences approved the study.
How to cite this article: Moradi A, Sajjadi H, Mohaqeqikamal SH, Vameqi M, Teshnizi SH, Qaedamini QR.A Study of labour children's social health referring to Non-Govermental Organization in support of children's rights in Tehran in 2014. J RafsanjanUniv Med Sci 2016; 14(10): 977-88. [Farsi]
S. Abolhassanizadeh, A. Mosadegh, M. Moradi, H. Hossieni Nave, M. Taati Moghadam,
Volume 14, Issue 11 (2-2016)
Volume 14, Issue 11 (2-2016)
Abstract
Background and Objectives: The major mechanisms which contribute to the spread of shigellosis are antibiotic resistance and transmission from person to person. The main purpose of this study was determination of antibiotic susceptibilities and survey of the prevalence of integrons class I and II genes in Shigella species isolated from patients in Kerman hospitals
Materials and Methods: In this cross-sectional study, 38 different Shigella species were collected from Kerman hospitals and were typed by serologically slide agglutination with specific antiesera. Antibiotic resistance patterns of shigella species were also evaluated by disk diffusion method. Detection of intI and intII genes was carried out by Polymerized Chain Reaction (PCR). Data analysis was done by Fisher,s exact test.
Results: In the current study 21 (55.2%) S.flexneri, 14 (36.8%) S.sonnei, 3(7.8%) S.boydii and no S.dysenteriae were detected by serologically slide agglutination and the majority of strains were resistant to ampicillin but were sensitive to ciprofloxacin. Of all 38 Shigella isolates, 21 (55.2%) species were demonstrated intI gene but 32 (84.2%) species presented intII gene after performing PCR.
Conclusion: According to high frequency of integrons and high resistance to antibiotics in shigella isolates, following health recommendations and prescribing correct antibiotics can prevent the extension of the diorrhetic disease resulted from shigella.
Key words: Shigella, PCR, Integron, Antibiotic resistance, Disk diffusion, Kerman
Funding: This research was funded by Kerman University of Medical Sciences.
Conflict interest: None declared.
Ethical approval: The Ethics Committee of Kerman University of Medical Sciences approved the study.
How to cite this article: Abolhassanizadeh S, Mosadegh A, Moradi M, Hossieni Nave H, Taati Moghadam M. Determination of Antibiotic Susceptibilities and survey of the frequency of integrons class I and II genes in Shigella species isolated from patients in Kerman hospitals, Iran in 2014: A Short Report. J RafsanjanUniv Med Sci 2016; 14(11): 989-96. [Farsi]
M. Asadpour, M. Sheikh Fathollahi, M. Rezaeian, H. Jafari Naveh, M. Mahboobi Rad, I. Amir Afzali,
Volume 14, Issue 12 (2-2016)
Volume 14, Issue 12 (2-2016)
Abstract
Background and Objective: One of the essential elements of improving the quality of education system is continuous assessment of educational process. The basic science courses are necessary for academic achievement, solving problems and clinical decision making in subsequent periods. Therefore, the purpose of this study was to investigate the factors influencing the results of the comprehensive examination of basic sciences from the perspective of medical students of Rafsanjan University of Medical sciences (RUMS).
Materials and Methods: This is a discriptive cross-sectional study in which all of the medical student in years 2005-2009 were recruited by census method (185 students). The data was collected via a questionnaire and a checklist, and then descriptive statistics and analysis of covariance were (ANCOVA) utilized for data analysis.
Results: Response rate in this study was 64.9%. The results indicated a negative association between the age and the score of the comprehensive examination of basic sciences (p<0.013). There was a statistically significant association between the score of the comprehensive examination of basic sciences and the importance of teaching of embryology and immunology courses from the students’ viewpoints, the significance of nutrition, and embryology courses, the extent to which students were interested in embryology, the size of syllabus of the histology course, and the quality of teaching in mycology, entomology, and health courses (p<0.05).
Conclusion: Due to the important role of basic science courses, in the development of competence of future doctors, and in order to develop and change medical education, establishing corrective steps are required in medical education.
Key words: Perspective of medical students, Effective factors, Results of the comprehensive examination of basic sciences, Rafsanjan
Funding: This research was funded by Rafsanjan University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study.
How to cite this article: Asadpour M, Sheikh Fathollahi M, Rezaeian M, Jafari Naveh H, Mahboobi Rad M, Amir Afzali I. A Survey on Factors Affecting the Results of Comprehensive Examination of Medical Basic Sciences in 2005 to 2009 Groups of Medical Students from the Students’ Viewpoints in Rafsanjan University Medical Sciences. J Rafsanjan Univ Med Sci 2016; 14(12): 1073-84. [Farsi]
P. Bastani, F. Lotfi, M. Moradi, M.s. Ahmadzadeh ,
Volume 15, Issue 8 (12-2016)
Volume 15, Issue 8 (12-2016)
Abstract
Background and Objective: The evaluation of the hospitals performance in order to improve the quality of services provided is of great importance. This study aimed to evaluate the performance of teaching hospitals affiliated to Shiraz University of Medical Sciences (SUMS) using Pabon Lasso graph before and after the implementation of the health system transformation plan.
Materials and Methods: This project is a descriptive cross-sectional study conducted on 14 hospitals in SUMS before and after the execution of health system reform plan during the years 2013-2014. The data were collected by referring to monthly activities and AVAB hospital site (hospital data and statistics) and analyzed by Pabon Lasso diagram and paired t-test.
Results: Before the implementation of the health system reform plan in 2013, of the total 14 hospitals, 14% were in zone 1 (poor performance) and 28% hospitals in zone 3 (good performance). In 2014, after the implementation of the health system reform plan, 21% of the hospitals were in zone 1 and 21% in zone 3. According to paired t test, the bed occupancy rate had significant difference before and after the health system reform plan (p=0.006).
Conclusion: Performance indicators in educational hospitals of SUMS were not in a good condition as compared to the standards. After health system reform plan, changes in the location of hospitals occurred. Therefore, it seems to be necessary that managers and policy makers improve efficiency and increase resource utilization.
Key words: Hospital, Performance assessment, Efficiency, Pabon-Lasso model, Health system reform plan, Shiraz
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Shiraz University of Medical Sciences approved the study
How to cite this article: Bastani P, Lotfi F, Moradi M, Ahmadzadeh M.S. The Performance Analysis of Teaching Hospitals Affiliated with Shiraz University of Medical Sciences Before and After Health System Reform Plan Using Pabon Lasso Model. J Rafsanjan Univ Med Sci 2016; 15(8): 781-92. [Farsi]
F. Faraji-Khiavi, S. Sharifi, E. Moradi-Joo,
Volume 15, Issue 11 (2-2017)
Volume 15, Issue 11 (2-2017)
Abstract
Background and Objective: Social capital may help organizational knowledge management via providing necessary platforms and facilitating the interchange of knowledge. So this research aimed to determine the relationship between social capital and effectiveness of knowledge management from the viewpoints of the teaching hospitals of Ahvaz managers.
Materials and Methods: This was a cross-sectional study which was carried out in 2015. The research population contained 120 Ahvaz teaching hospitals managers. Data collection tools incorporated demographic questionnaire, the effectiveness of knowledge management processes questionnaire, and social capital questionnaire. Non-parametric Spearman’s correlation coefficient as well as Mann–Whitney and Kruskal–Wallis tests were used for data analysis.
Results: No significant correlation was seen between social capital and effectiveness of knowledge management practices (P>0.05). However, Organizational network showed a significant poor correlation with organizational understanding (rs=0.307, p=0.001), people-oriented approach (rs=0.185, p=0.043), and the effectiveness of knowledge management practices (rs=0.333, p=0.011). Furthermore, Organizational trust demonstrated a significant poor correlation with organizational understanding (rs=0.229, p=0.012) and innovative culture development (rs=0.201, p=0.027). Finally, social capital showed a weak correlation with organizational understanding (rs=0.230, p=0.012).
Conclusion: Managers of teaching hospitals in Ahvaz estimated knowledge management practices as relatively efficient and social capital as appropriate. It seems, in teaching hospitals, managers may need to emphasize on development of organizational networks, educating proper communication and increasing organizational confidence for effectiveness of knowledge management practices.
Key words: Social capital, Practices effectiveness, Knowledge management, Teaching hospital, Ahvaz
Funding: This research was funded by Ahvaz Jundishapur University of Medical Sciences (AJUMS).
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Ahvaz Jundishapur University of Medical Sciences approved the study.
How to cite this article: Faraji-Khiavi F, Sharifi S, Moradi-Joo E. The Relationship Between Effectiveness of Knowledge Management Practices and Social Capital from Managers' Viewpoints in Teaching Hospitals of Ahvaz in 2015. J Rafsanjan Univ Med Sci 2017; 15(11): 1049-60. [Farsi]
S. Amanpour, M. Rad, T. R. Mirshekari, M. Torabi Parizi, S. Fardisi, S. Shafazand,
Volume 15, Issue 11 (2-2017)
Volume 15, Issue 11 (2-2017)
Abstract
Background and Objective: Salivary gland tumors are an important part of oral pathology. The role of these cells in tumorigenesis has been reported but enough investigations have not been conducted about the role of mast cells in salivary gland tumors. This research aimed to study mast cells density in the most prevalent salivary gland tumors.
Materials and Methods: In this cross-sectional study, 70 cases of most common benign and malignant salivary gland tumors and 10 cases of normal salivary gland were enrolled from Kerman and Shiraz hospitals from 2005 to 2015. Sections were stained and data was analyzed using one-way ANOVA, followed by Tukey's multiple comparison test, chi-square, independent, and paired t-test.
Results: The average mast cells count increased significantly in salivary gland tumors compared to normal salivary glands both in intra and peri-tumoral stroma (p=0.001). There was a significant difference between benign and malignant tumors in peri-tumoral stroma (p=0.002) but not in intra tumoral stroma. In comparison between mucoepidermoid carcinoma and adenoid cystic carcinoma, there was a significant difference in peri-tumoral stroma (p=0.015) and not in intra-tumoral stroma. Mast cells density was significantly higher in grade I of mucoepidermoid carcinoma compared to the grades II and III (p=0.001).
Conclusion: Mast cells density seems to have relation with tumorgenesis process and grade of malignancy.
Key words: Pleomorphic adenoma, Mucoepidermoid carcinoma, Adenoid cystic carcinoma, Mast cells, Kerman
Funding: This study was funded by Kerman University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Kerman University of Medical Sciences approved the study.
How to cite this article: Amanpour S, Rad M, Reza Mirshekari T, Torabi Parizi M, Fardisi S, Shafazand S. Survey of Mast Cells Density in the Most Prevalent Benign and Malignant Salivary Gland Tumors in Southeast of Iran 2005-2015. J Rafsanjan Univ Med Sci 2017; 15(10): 1027-38. [Farsi]
Gh. Asgari, S. Akbari, J. Faradmal, H. Almasi, Z. Daraee ,
Volume 15, Issue 12 (3-2017)
Volume 15, Issue 12 (3-2017)
Abstract
Background and Objective: Chemical dyes used in the textile wastewater besides having harmful effect on the environment, have carcinogenic and mutagenic effects. Methylene blue has harmful effect on living organisms in short period of exposure. The goal of this study was optimization of the catalytic ozonation process by pumice modified by magnesium nitrate in removal of methylene blue dye based on Taguchi statistical model.
Materials and Methods: In this experimental study ozonation process was in a batch ozonation reactor. The prepared pumice was crushed and pulverized by standard ASTM (American Society for Testing and Materials) sieves at range of 70 mesh, then modified by magnesium nitrate. Effective factors such as reaction time, initial dye concentration, adsorbent dose, and initial pH at 4 different levels were considered using an L-16 Taguchi method. Residual concentration of contaminants was read using a spectrophotometer at a wavelength of 663 nm. Analysis of data was performed using one- way variance and calculation of S/N (signal- to- noise) rate.
Results: The results showed best conditions for removal dye were at contact time of 15 min, pH of 10, dye concentration of 50 mg/l,and adsorbent dosage of 0.7 g/L and efficiency of dye removal was 98%. Analysis of variance results indicated that the reaction time was the most important variable influencing the dye removal percentage with the contribution value of 51.8% and pH was the least important variable influencing the dye removal with the contribution value of 3.8%
Conclusion: The results showed that ozonation process can be a selective method to reduce the concentration of pollutants in textile wastewater effluent.
Key words: Catalytic ozonation, Methylene blue, Magnesium nitrate, Pumice
Fundings: This research was found by Hamedan University of Medical Sciences.
Conflict of Interest: None declared.
Ethical approval: The Ethics Committee of Hamedan University of Medical Sciences approved the study.
How to cite this article: Asgari Gh, Akbari S, Faradmal J, Almasi H, Daraee Z. Removal of Methylene Blue Dye from Wastewater of Textile Industry in Catalytic Ozonation Process by Pumice Modified by Magnesium Nitrate. J Rafsanjan Univ Med Sci 2017; 15(10): 1095-106 [Farsi]
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