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Volume 3, Issue 1 (12-2004)
The Prevalence of Hepatitis B Infection in Patients Suffering from Lichen Planus in Kerman During the Year 1381
I. Esfandiarpour MD1*, Z. Rahnama MD2, F. Fahimy MD3, Z. Salari GP4
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1- Associated Professor, Dept. of Dermatology, Kerman University of Medical Sciences, Kerman, Iran
2- Assistant professor, Dept. of Dermatology, Kerman University of Medical Sciences, Kerman, Iran
3- Assistant professor, Dept. of Radiology, Kerman University of Medical Sciences, Kerman, Iran
4- General Physician, Kerman University of Medical Sciences, Kerman, Iran
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Background: Lichen planus (LP) is an inflammatory papulosquamous which has been found to be associated with liver disease, particularly hepatitis B (HBV) infection in several studies.
Regarding the increasing of the prevalence of hepatitis B in our community, and the importance of the infection caused by this virus, which is among the man health problems we conducted a descriptive and cross-sectional study in Kerman population for evaluatiof the prevalence of cases with positive hepatitis B virus surface antigen (HBsAg) in patients suffering from LP compared to the general population, that is 1-2%.
Materials and Methods: 120 patients with LP (case group) and 183 healthy volunteer blood donors (control group) were studied during 10 months in 1381 in specialized dermatology clinics of Kerman city.
LP was diagnosed by clinical manifestation, physical examination and skin biopsy. HBsAg was detected in cases and control group by Elisa method.
Results: The mean age of the individuals was 35.75 ± 1.45 for case group and 32.7 ± 0.7 for control group. 57(47.5%)of patients in case group were female and 63 (52.5%) were male. In control group 46 (25%) were female and 137 (75%) were men.
The results showed that the most common site of Lp involvement was upper limb (67.5%) and the most frequent clinical types were mucosal (67.5%) and classical forms (65%) respectively.
One of the patients with Lp (0.8%) and four controls (2.2%) were HBsAg positive. These values were not statistically significant.
Conclusion: Our findings indicated that a search for HBV infection in all patients with lichen planus is not neseccary. A large multicentric studies should be conducted in other areas of the country.
Key words: Hepatitis B, Lichen planus, Kerman.
Volume 5, Issue 2 (6-2006)
The Bio-positive Effects of Burned Radioactive Lantern Mantle Powder on the Wound Healing in Rat
SMJ. Mortazavi PhD [1] , MR. Rahmani MSc [2] , A. Rahnama MD [3] , J. Ahmadi Kahnali GP [4] , HR. Rashidinejad MD [5] , MM. Aghaiee GP [6] , AA.
Recived: 23/07/2005 Revised: 14/02/2006 Accepted: 27/02/2006
Background and Objective: Poor educated people in some parts of Iran use burned mantles as a wound healing powder to prevent the bleeding and infections caused by injuries. Some lantern mantles contain low levels of radioactive thorium for maximizing the light output, while non-radioactive mantles contain yttrium. Although radioactive lantern mantles may cause a minimal radiation health hazard, it is generally believed that it would be dangerous when inhaled or ingested. This study was conducted to evaluate the effect of burned radioactive lantern mantles on wound healing.
Materials and Methods : Twenty rats were divided randomly into two groups of 10 animals each. After inducing general anesthesia, full thickness excision wound (314±31.4 mm2) was made on the dorsal neck in all animals. The 1st group received topical burned radioactive lantern mantle powder at 1st-3rd day after wound excision. The presence of radioactivity in the mantle was detected using a Monitor-4 survey meter. The 2nd group received non-radioactive lantern mantle powder at the same days. Accurate blind surface measurement of the wounds was performed by transparency tracing to assess the wound healing at 1st, 3rd, 7th, 10th and 15th days after excision.
Results: A progressive reduction in the wound area of both groups was observed. However, for thorium treated group, the rate of recovery was significantly enhanced compared to that of the control group. Although this value in the thorium group was not significantly different from that of the control group at the 3rd and 5th days after wounding, a statistically significant difference was observed between these two groups at the day7, day10 and day 15. The mean wound surface in thorium and control groups were 150.20±15.87 and 186.37±12.68 mm2 at day7 (p<0.001), 92.90±15.97 and 134.12±14.19 mm2 at day 10 (p<0.001), 1.40±0.41 and 8.56±2.04 mm2 at day15 after wounding, respectively (p<0.01).
Conclusions: These findings suggest that low-level radioactive burned mantle accelerates wound healing in rats. However, as thorium oxide is a known human carcinogen, more research is needed to clarify if low levels of radioactive burned mantle can be utilized for enhancing wound healing.
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Key words: Lantern Mantle, Wound Healing, Thorium, Radioactivity[1] - Associate Prof. Dept. of Biochemistry-Biophysic, University of Medical Sciences, Rafsanjan
Corresponding author: Tel: (0391) 8220013, Fax: (0391) 8220008, E-mail: jamo23@lycos.com
[2] - Academic Member, Dept. of Physiology, University of Medical Sciences, Rafsanjan
[3] - Assistant
[4] - General
[5] - Assistant Prof.
[6] - Intern, University of Medical Sciences, Rafsanjan
[7] - Assistant
[8] - Instructor, Dept. of Radiology, University of Medical Sciences, Rafsanjan
Volume 10, Issue 3 (7-2011)
H . Yazdi Moghaddam [1] , F . Rahnamai Rahsepar [2] , A . Heydari [3]
Received: 11/07/2009 Sent for Revision: 23/01/2010 Received Revised Manuscript: 20/11/2010 Accepted: 26/12/2010
Background and Objectives : Delivery is one of the greatest events in the life of a pregnant woman. Although it is considered to be a natural phenomenon, it is potentially dangerous. Entonox gas used for pain relief and is reasonably effective in labor analgesic practice. The purpose of this study was to compare the APGAR score of the neonates were born to mothers who treated with entonox gas with those who their mothers did not received this gas.
Materials and Methods : In this semi-experimental study, 270 pregnant women hospitalized at the labor ward of Shahidan Mobini Hospital of Sabzavar were included using simple available sampling method. They were then separated into two groups, case and control, based on their specifications. The data gathering tool for this study was a questionnaire of "investigating the effect of entonox gas as a no-pain labor agent on Neonates’ APGAR" which is individually filled out for each patient by obstetrician colleagues. The APGAR scores of infants were recorded at 1st, 5th, and 20th minutes. The statistical analysis of data was performed by t-test, Chi-Square and Fisher tests using SPSS software.
Results : That there were no significant differences between the two groups in terms of age, pregnancy period, and using labor induction. The APGAR scores of the case group at 1st, 5th, and 20th minutes postpartum were significantly higher than the control group (p< 0.05).
Conclusion : Regarding the importance of controlling pain during delivery and its effect on reducing the mother’s stress, using of entonox gas can be a good option for relieving pain during delivery moreover, it can improve the APGAR score.
Key words : Entonox Gas, APGAR, No-pain Labor
Funding: This research was funded by Sabzevar University of Medical Sciences. .
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Sabzevar University of Medical Sciences approved the study.
How to cite this article : Yazdi Moghaddam H, Rahnamai Rahsepar F, Heidari A . Studying the Effect of Entonox Gas on the APGAR of the Neonates . J Rafsanjan Univ Med Sci 2011 10(3): 165-74. [Farsi]
1- Academic Member, Dept. of Operation Room, School of Allied Medical Sciences, Sabzevar University of Medical Sciences, Sabzevar, Iran
Corresponding Author, Tel: (0571) 4446030, Fax: (0571) 4446008, E-mail: ha_yazdimoghaddam@yahoo.com
2- Academic Member, Dept. of Nursing, Nursing & Midwifery School, Sabzevar University of Medical Sciences, Sabzevar, Iran
3- Assistant Prof., Dept , of Nursing, Nursing & Midwifery School, Mashhad University of Medical Seiences, Mashhad, Iran
Volume 11, Issue 3 (7-2012)
Background and Objectives : Post operative nausea and vomiting (PONV) are important complications of surgeries causing an unpleasant experience for many patients and may lead to a delays in the discharge from hospital. Different medical and non-medical interventions are applied to prevent this problem. In this study, we compared the antiemetic effects of ondansetron, metoclopramide and dexamethasone in children undertaken strabismus surgey.
Materials and Methods: In this double-blind randomized clinical trial study , 111 children belonging to ASA class I and II between the age group of 2–15 years old and scheduled for elective surgery of strabismus were Ethical approval and written informed consent forms were obtained . The participants were then randomly divided into three groups ondansetron, metoclopramide and dexamethasone. Dexamethasone was injected at the beginning of the operations, and the other two medicines were injected 30 minutes prior to the end of surgery. In the recovery wards, the frequency of nausea and vomiting and any therapeutic interventions for each patient were recorded at the following times 1h, 1-6h, 6-12h, and 12-24h post-op. The obtained data was ultimately analyzed by Chi - squared and Kruskall statistical tests.
Results : There was no significant differences among the three groups in terms of age, weight and sex. Patients in ondansetron group had the lowest frequency of PONV (7.8%) and the need for therapeutic interventions (3.6%). These values for dexamethasone group were 12.6%, 13.5% and for the metoclopramide group were 13.5%, 10.8% respectively.
Conclusion: Ondansetron is associated with a lower rate of PONV, more satisfaction, less expenditure, and less therapeutic interventions .
Key words: Strabismus, Post operative nausea and vomiting, Ondansetron, Dexamethasone, Metoclopramide
Funding: This research was funded by Guilan University Research Center, Guilan University of Medical sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Guilan University of Medical Sciences approved the study.
How to cite this article : Haddadi S, Marzban Sh, Khorramnia S, Rahnama O. Comparison of the Antiemetic Effects of Ondansetron, Metoclopramide and Dexamethasone in Children Undertaken Strabismus Surgery. J Rafsanjan Univ Med Scie 2012 11(3): 187-96. [Farsi]
Volume 11, Issue 4 (8-2012)
Background and Objectives: One of the most common causes of Abnormal Uterine Bleeding (AUB) in adolescents is endometrial carcinoma. Evaluation of endometrial cancer in women of childbearing age, especially in the presence of other risk factors, is necessary. This study aimed to determine the frequency of pathological specimens of diagnostic curettage in patient admitted to Niknafs hospital and determining the predisposing factors for malignant cases .
Materials and Methods: In this descriptive study, all the patients over 35 with complaint of abnormal bleeding in Niknafs hospital, the only maternity hospital in Rafsanjan, who had the diagnostic curettage performed on them from 2006 to 2009, were studied. Data were extracted from the patients' history of records and the samples were referred to the pathology center of Ali-ebn-abitaleb hospital and by questionnaire. Data were analyzed using descriptive statistics.
Results: Most pathology reports (45.5%) were hyperplasia and 4% cancer and 24.6% were normal. Most complaints was menorrhagia bleeding (53.6%). Average of Fertility number was 4.9±2.4. Thirteen and one tenth percent of cases were taking contraceptive pills and 4.7% were diabetic and 16.5% had hypertension. Of all cases, only one case had the history of breast cancer in her and there was no case of cancer in the family history. Seventy five percent of endometrial cancer were affected with the complaint of menorrhagia. People with normal endometrium had lowest fertility rate and were younger.
Conclusion: The age of the patients and the multiplicity of their fertility with the diagnosis of abnormal endometrial curettage in pathological specimens showed a direct relationship. There were no direct relationships between oral contraceptive use and incidence of diabetes in people with cancer.
Key words: Uterine Bleeding, Diagnostic Curettage, Pathological Samples
Funding : This study was funded by Rafsanjan University of Medical Sciences.
Conflict of interest : Non declared.
Ethical approval: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study.
How to cite this article : Zare Rashkooeih R. Rezaeian M, Rahnama A, Manshori A. Salajeghe M, Arab Baniasadi F, Vatan A . Prevalence of Pathological Specimens of Diagnostic Curettage in Patients Admitted to Niknafs Hospital (Short Report) . J Rafsanjan Univ Med Scie 2012 11(4): 403-10. [Farsi]
Volume 12, Issue 8 (10-2013)
Background and Objective: Coronary artery disease (CAD) in young people shows a different clinical, angiographic and pathophysiologic behavior in comparison to older age patients. Lipoprotein a (LPa) as a risk factor has a role for CAD so its serum measurement can be valuable for detecting people dispose to this group of diseases. Materials and Methods: We did a cross-secotinal study on a 120 people in 4 equal groups (patients with myocardial infarction and normal population, more and less than 45 years old). The data collected according to clinical examination and results of serum LPa, LDL, HDL levels. Then, data analyzed using to descriptive and analytical statistical tests i.e. the t test. Results: LPa level in both groups of normal people was 28.53±3.39 and both group of patients was 47.88±5.12 mg/dl (p= 0.015). Average LPa level between both groups of women less than 45 age old, in control 44.40±4.66 and patients group 81.03±12.14 was significant (p= 0.004). This value was significant between both group of women more than 45 years old in control 24.95±3.07 and patients groups 34.73±2.84 too (p= 0.001). Average LPa level between men less than 45 years in control 17.38±1.94 and patients groups 31.11±2.73 (p= 0.010) and men more than 45 years, in control 27.2±3.91 and patients groups 53.62±6.01 (p= 0.007) that was significant. Conclusion: Our study showed remarkable LPa level in coronary artery disease patients. Key words: Coronary artery disease risk factors, Lipoprotein a, Premature myocardial infarction Funding: This research was funded by Rafsanjan University of Medical Science. Conflict of interest: None declared. Ethical approval: The Ethics Committee of Rafsanjan University of Medical Science, approved the study. How to cite this article: Mirzaei M, Rahnama A, Esmaeelian F, Bakhsh H. Serum Level of Lipoprotein a (LPa) in Patients with Premature Myocardial Infarction. J Rafsanjan Univ Med Sci 2013 12(8): 655-66. [Farsi]
Volume 12, Issue 9 (12-2013)
Background and Objective: Appendicitis is one of the most common causes of emergency abdominal surgery in children. Diagnosis before surgery has always been a problem. One of the symptoms in dealing with patients with suspected appendicitis is dry and scaly lips. Therefore, the present study was conducted to investigate the relationship of this sign with appendicitis.
Materials and Methods: This cross-sectional study was conducted in a three-month period, all the patients under 18 admitted with complaints of abdominal pain were entered into the study. Possible diagnosis was appendicitis based on history, clinical examinations, laboratory tests and abdominal sonography. Alvarado score pediatric appendicitis score(PAS) and pathological results were recorded. Collected data were analyzed by descriptive statistics using SPSS software.
Results: Out of 25 patients who entered the study, 11 patients (44%) were males and 14 patients (56%) were females with mean age and SD of 11.88± 4.77 years old. The pathology reports were as follows: 13 patients (52% ) acute appendicitis, 10 patient (40%) acute suppurative appendicitis with periappendicitis, one patient (4%) ruptured appendicitis and for one patients (4%) nomal appedix . Pain shifting in 20 patients (80%) and dry lips in 22 patients (88%) were observed. Alvarado average score of the patients was 7.04± 2.28 and PAS average score was 7.24± 1.71.
Conclusion: Early diagnosis and appendectomy before gangrene or rupture of the appendix will reduce complications of this disease. Therefore, early diagnosis of this disease is important. Sign of dry lips in 22 patients (88%) compared with other signs and symptoms is important. Based on this study it is concluded that dry lips can be a diagnostic sign along with other signs . According to the findings of this study further studies are recommended.
Key words: Dry lips, Acute appendicitis, Children
Funding: This research was funded by Rafsanjan University of Medical Sciences .
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study.
How to cite this article : Amouei AH, Rezahoseini O , Rahnama A, Tavakoleian Ferdosieh V. Evaluation of Dry Lips as a New Sign in Clinical Diagnosis of Acute Appendicitis in Children: A Short Report . J Rafsanjan Univ Med Sci 2013 12(9): 769-76. [Farsi]
Volume 18, Issue 4 (6-2019)
Background and Objectives: The quantitative and qualitative data on urban solid waste is one of the essential steps in the scientific management of solid waste. The purpose of this study was to survey the qualitative and quantitative production of solid waste in Mashhad.
Materials and Methods: In this descriptive study, in order to examine the quality of the samples, the separated materials were weighed. For physical analysis, samples were randomly assigned to a volume of 0.125m3 inside the density gauge. Solid wastes were sorted according to the type and placed in the nylon and weighed. Data were analyzed using Chi-square test.
Results: According to the results,the mean of the solid waste produced in summer was 2190 ± 126.17 and in winter 1890 ± 100.63 tons per day. The highest amount of waste was related to corrosive materials and the minimum amount pertaining to glass. The highest type of heavy metal in the leach of Mashhad city was Ni (3.1 mg/L).
Conclusion: Due to high amount of garbage materials in solid waste, compost production is recommended to be attended.
Key words: Solid waste, Quantity, Quality, Mashhad
Funding: There was no funding for this study.
Conflict of interest: None declared
Ethical approval: This project was not registered.
How to cite this article: Rezaee E, Rahnama Bargard Z, Kharghani M, Aghalari Z. The Survey of Qualitative and Quantitative Production of Solid Waste in Mashhad in 2016: A Short Report. J Rafsanjan Univ Med Sci 2019; 18 (4): 407-14. [Farsi]
Volume 20, Issue 3 (6-2021)
Background and Objectives: According the importance of iodine monitoring in the prevention of iodine deficiency disorders, this study aimed to evaluate the clinical iodine and goiter deficiency in 7-12 year-old students in Rafsanjan in 2018-19.
Materials and Methods: The statistical population of this cross-sectional study included all students of 7-12 years old who were covered by Rafsanjan Education Management in 2018. From 21218 students aged 7 to 12 years living in the city, 1203 students (601 boys and 602 girls) based on inclusion criteria were enrolled in the study. After obtaining informed consent from the parents, the students were examined clinically by an internal trained resident. In this study, the presence and severity of goiter were evaluated based on the World Health Organiaztion classification. Then, 10 ml of the morning urine sample of 10% of all samples was taken to measure iodine by acid digestion method.
Results: The mean and standard deviation of age of participants was 9.48±1.71. In addition, mean and standard deviation of urinary iodine was 183.33±80.52 Ug / dl. In the study of the prevalence of goiter in the community, 87.1% (1047 samples) had no goiter, 9.7% (117 samples) had D1 grade and 3.2% (39 samples) had D2 grade. It was also found that the prevalence of goiter was not statistically significant in terms of age and sex.
Conclusion: The findings of this study indicate that the iodine deficiency control program and consumption of iodized salt has caused a significant decrease in the prevalence and severity of goiter, and also adequacy of the received iodine, given a marked increase in urinary iodine excretion in Rafsanjan city.
Key words: Iodine, Goiter, Students, Rafsanjan
Funding: This study did not have any funds.
Conflict of interest: No conflict.
Ethical approval: The Research Committee of Rafsanjan University of Medical Sciences approved the study (code: 1397073).
How to cite this article: Karimifard M, Chahkhoei S, Ebrahimynejad F, Sayadi A, Rahnama A, Shafipour M, Talebizadeh N. Frequency of Goiter and Urine Iodine Deficiency in 7-12 Years Old Students of Rafsanjan: 2018-2019: A Descriptive Study. J Rafsanjan Univ Med Sci 2021; 20 (3): 325-38. [Farsi]
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