TY - JOUR T1 - Solid-Pseudo-Papillary Tumor of Pancreas: A Case Report TT - تومورSolid-Pseudopapillary پانکراس:گزارش یک مورد نادر JF - RUMS_JOURNAL JO - RUMS_JOURNAL VL - 8 IS - 4 UR - http://journal.rums.ac.ir/article-1-5352-en.html Y1 - 2009 SP - 327 EP - 334 KW - Solid – Pseudo Papilary Tumor KW - Gruber-Frantz Tumor KW - Pancreatic Tumors N2 - Background and Objectives: Solid Pseudo-Papillary Tumor (SPPT) is a benign and rare neoplasm which transforms to malignant from in fewer than 1 to 2 percent of cases. In more than 90% of the cases, it appears in young women ages 20 to 40 years old. Although SPPT is a benign tumor, it has special potential for mild malignancy. Case Report: The patient was an 18-year old woman with abdominal mass, headache, fever, chill, decreased appetite, pallor and dysuria who referred to Shahid Sadooghi hospital of Yazd, Iran in July 2007. In examination, a firm inflated, mobile, and painless mass with distinct borders was palpated in the left upper abdominal quadrant. This mass was 16 cm in diameter. In CT scan a large hypodense mass with thick wall and crossing the center line on the right side of spine was prominent. Microscopic evaluations after the surgery showed tumoral cells of small polyhedral core elliptical, pseudopapillary processes trabeculs with diffused fibrosis, atrophy acinar and mild infiltration of chronic inflammatory cells in the tumors margins. Conclusion: The final diagnosis in this patient was SPPT, a primary neoplasm of the pancreas. Its etiology is unknown and has low potential to turn into malignant form. It should be considered, especially in young women. Complete removal of the mass is the preferred treatment of the patients. Patients with local recurrence or metastasis can have long term survival after complete removal of the mass. Key words: Solid – Pseudo Papilary Tumor, Gruber-Frantz Tumor, Pancreatic Tumors M3 ER -