Journal of Rafsanjan University of Medical Sciences
مجله دانشگاه علوم پزشکی رفسنجان
JRUMS
Medical Sciences
http://journal.rums.ac.ir
69
journal69
1735-3165
2008-7268
10.61186/jrums
fa
jalali
1401
4
1
gregorian
2022
7
1
21
4
online
1
fulltext
fa
ارزیابی میزان تجمع برخی فلزات سنگین در تعدادی از گیاهان دارویی پرمصرف و ریسک خطر آنها در کودکان و بزرگسالان استان سیستان و بلوچستان در سال 1400: یک مطالعه آزمایشگاهی
Evaluation of the Amount of the Accumulation of Some Heavy Metals in a Number of Commonly Used Medicinal Plants and Their Risk in Children and Adults in Sistan and Baluchestan Province in 2021: A Laboratory Study
تغذيه
تغذيه
پژوهشي
Research
<span style="font-size:10pt"><span style="line-height:130%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">زمینه و هدف: </span></span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">استفاده از گیاهان دارویی در بین مردم در حال افزایش است و وجود آلاینده­هایی چون فلزات سنگین در آن­ها می­تواند بر روی سلامت مصرف­کنندگان مؤثر باشد. بنابراین، هدف از این مطالعه تعیین میزان تجمع برخی فلزات سنگین در چند گیاه دارویی پرمصرف و ارزیابی ریسک خطر آن­ها در</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">کودکان و </span></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">بزرگ</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%"></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">سالان</span></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> بود.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">مواد و روش­ها:</span></span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> در این مطالعه آزمایشگاهی، 5 نوع گیاه دارویی و از هر نوع 4 نمونه از مناطق مختلف استان سیستان و بلوچستان در بهار 1400 جمع­آوری شدند. نمونه­ها در آزمایشگاه آماده­سازی و هضم اسیدی شدند و از نظر غلظت فلزات سنگین کادمیوم، سرب، مس، ارسنیک و جیوه توسط دستگاه­های­ طیف­سنج مبتنی بر پلاسما با آشکارساز نشر نور</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">و طیف­سنج جذب اتمی با شعله</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">ارزیابی</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">گردیدند و با استفاده از آزمون </span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">Kolmogorov-Smirnov</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> و آزمون </span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">t</span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> تک نمونه­ای و آنالیز واریانس یک­طرفه،</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">تحلیل آماری انجام و ریسک خطر هر یک از این فلزات به واسطه مصرف آن­ها در کودکان و بزگ</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%"></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">سالان برآورد شد.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">یافته­ها:</span></span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> میانگین میزان فلزات سنگین در انواع مختلف گیاهان بسیار متغیر و کمتر از سطح مجاز برای هر دو گروه سنی کودکان و بزرگ</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%"></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">سالان بود. میزان</span></span></span> <span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">(</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">THQ</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">) </span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">Target Hazard Quotient</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> برای هر یک از فلزات و مقدار (</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">HI</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">) </span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">Hazard Index</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> برای مجموع فلزات، در تمامی انواع گیاهان دارویی، با اختلاف زیادی کمتر از میزان </span></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">مجاز</span></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> (1=</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%">THQ/HI</span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">) بود.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">نتیجه­گیری: </span></span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">گیاهان دارویی استان سیستان و بلوچستان دارای سط</span></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">و</span></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">ح پایینی از آلودگی به فلزات سنگین می­باشند و</span></span></span><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> از این لحاظ</span></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> مصرف آن­ها برای کودکان و بزرگ</span></span></span><span dir="LTR" style="font-size:9.0pt"><span style="line-height:130%"></span></span><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">سالان می­تواند ایمن باشد.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">واژه­های</span></span></span></b><b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:"> کلیدی: </span></span></span></b><span lang="AR-SA" style="font-size:11.0pt"><span style="line-height:130%"><span b="" nazanin="" style="font-family:">فلزات سنگین، گیاهان دارویی، ارزیابی خطر، امنیت غذایی</span></span></span> <span lang="AR-SA" style="font-size:1.0pt"><span style="line-height:130%"><span style="font-family:"B Nazanin""></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:150%">Background and Objectives</span></b><b><span style="font-size:12.0pt"><span style="line-height:150%">:</span></span></b> <span lang="EN" style="line-height:150%">The use of medicinal plants is increasing among people and the presence of pollutants such as heavy metals in them can affect the health of consumers. Therefore, the purpose of this study was to determine the amount of accumulation of some heavy metals in a number of commonly used medicinal plants and to evaluate their risk in children and adults.</span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span lang="EN" style="line-height:150%">Materials and Methods: </span></b><span lang="EN" style="line-height:150%">In this laboratory</span> <span style="line-height:150%">study</span><span lang="EN" style="line-height:150%">, 5 types of medicinal plants, 4 samples of each type, were collected from different regions of Sistan and Baluchestan province in the spring of 2021. The samples were prepared and acid digested in the laboratory and </span><span style="line-height:150%">were evaluated </span><span lang="EN" style="line-height:150%">in terms of the concentration of Cd, Pb, Cu, As, and Hg</span> <span lang="EN" style="line-height:150%">by inductively coupled plasma-optical emission spectrometry (ICP-OES) and flame atomic absorption spectroscopy (FAAS). Data was analyzed by using Kolmogorov-Smirnov, one-sample t-test, and one-way ANOVA, and the risk of each of these metals was estimated due to their consumption in children and adults.</span><span style="line-height:150%"></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span lang="EN" style="line-height:150%">Results: </span></b><span style="line-height:150%">The average amount of heavy metals in different types of plants was very variable and lower than the permissible level for both children and adults. </span><span lang="EN" style="line-height:150%">Target hazard quotient (THQ) for each of the metals and </span><span style="line-height:150%">Hazard Index</span> <span lang="EN" style="line-height:150%">(HI) for all metals, in all types of medicinal plants, were significantly lower than the permissible level (THQ/HI=1).</span><span style="line-height:150%"></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span lang="EN" style="line-height:150%">Conclusion: </span></b><span lang="EN" style="line-height:150%">Medicinal plants of Sistan and Baluchestan province have low levels of heavy metal contamination and their consumption is completely safe for children and adults.</span><span lang="AR-SA" dir="RTL" style="line-height:150%"></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:150%">Key words: </span></b><span style="line-height:150%">Heavy metals, Medicinal plants, Risk assessment, Food security</span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:150%">Funding:</span></b><span style="line-height:150%"> This study was funded by Islamic Azad University of Zahedan, Iran.</span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:150%">Conflict of interest:</span></b><span style="line-height:150%"> None declared</span><span lang="EN" style="line-height:150%">.</span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span lang="EN" style="line-height:150%">Ethical approval: </span></b><span style="line-height:150%">The Ethics Committee of Islamic Azad University of Zahedan approved the study (IR.IAU.ZAH.REC.1400.043).</span><b><span lang="AR-SA" dir="RTL" style="line-height:150%"></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="line-height:150%">How to cite this article: </span></b><span style="line-height:150%">Habibollahi Mohammad Hossein. Evaluation of the Amount of the Accumulation of Some Heavy Metals in a Number of Commonly Used Medicinal Plants and Their Risk in Children and Adults in Sistan and Baluchestan Province in 2021: A Laboratory Study. </span><i><span style="line-height:150%">J Rafsanjan</span></i><span style="line-height:150%"> <i>Univ Med Sci</i> 2022; 21 (4): 460</span><span style="line-height:150%"><span calibri="" style="font-family:">-74.</span></span><span style="line-height:150%"> [Farsi]</span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-size:1.0pt"><span style="line-height:150%"></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:150%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-size:1.0pt"><span style="line-height:150%"></span></span></span></span></span></span></span><br>
فلزات سنگین, گیاهان دارویی, ارزیابی خطر, امنیت غذایی
Heavy metals, Medicinal plants, Risk assessment, Food security
461
474
http://journal.rums.ac.ir/browse.php?a_code=A-10-5896-1&slc_lang=fa&sid=1
MohammadHossein
Habibollahi
محمدحسین
حبیب الهی
mohamadhossein.habib@gmail.com
6900319475328460050294
6900319475328460050294
Yes
Islamic Azad University, Zahedan, Iran
دانشگاه آزاد اسلامی واحد زاهدان