Journal of Rafsanjan University of Medical Sciences
مجله دانشگاه علوم پزشکی رفسنجان
JRUMS
Medical Sciences
http://journal.rums.ac.ir
69
journal69
1735-3165
2008-7268
10.66224/jrums
fa
jalali
1403
3
1
gregorian
2024
6
1
23
2
online
1
fulltext
fa
پیامدهای نوزادی و مادری قبل و حین همهگیری کووید-19: یک مطالعه مقطعی
Neonatal and Maternal Outcomes Before and After COVID-19 Pandemic:
A Cross-Sectional Study
اطفال
Pediatrics
توصيفي
Description
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">زمینه و هدف: </span></span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">بیماری کووید-19 باعث افزایش نگرانی در مورد گروه‏های آسیب‏پذیر جامعه از جمله زنان باردار و نوزادان شد. این مطالعه با هدف تعیین پیامدهای مادری و نوزادی در نوزادان بستری در بیمارستان علی‏ا‏بن‏ابی‏طالب(ع) شهرستان رفسنجان قبل و بعد از همهگیری کووید-19 انجام شد. </span></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><a name="_Hlk141796420"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">مواد و روش­ها: </span></span></span></span></b></a><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">در این مطالعه مقطعی، 337 نوزاد بستری در بیمارستان علی</span></span></span></span><span dir="LTR" lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">‎</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">ابن‏ابی‏طالب(ع) در 3 ماهه اول سال 1398 </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">(قبل از شروع </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">همه­گیری </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">کووید-19) </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">و 194 نوزاد بستری در 3 ماهه اول سال 1399 </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">(بعد از شروع </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">همه­گیری </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">کووید-19) مورد بررسی قرار گرفتند. </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">مشخصات دموگرافیک، عوارض مادری و نوزادی از پروندهها استخراج شد و از آزمون </span></span></span></span><span dir="LTR" style="color:black">t</span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black"> دو نمونه مستقل و آزمون مجذور کای</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black"> برای آنالیز داده­ها استفاده شد. </span></span></span></span><span dir="LTR" style="color:black"></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">یافته‏ها:</span></span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black"> امتیاز آپگار دقیقه اول و دقیقه پنجم </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">در طی دوران کووید-19 به­طور معنادار کاهش یافته بودند </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">(</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">001/0></span></span></span></span><span dir="LTR" style="color:black">P</span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">)</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">، در حالی­که </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">مرگ نوزاد (</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">003/0</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">=</span></span></span></span><span dir="LTR" style="color:black">P</span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">)</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black"> و آسفیکسی در زمان تولد (</span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">001/0></span></span></span></span><span dir="LTR" style="color:black">P</span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">) در دوران کووید-19 به­طور قابل توجهی افزایش یافته بودند. فراوانی پارگی زودرس غشاءهای جنینی، پره­اکلامپسی، اکلامپسی، ابتلاء به دیابت در مادران باردار قبل و بعد از همه­گیری </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">کووید-19 </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">از نظر آماری معنادار نبود (05/0<</span></span></span></span><span dir="LTR" style="color:black">P</span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">). </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black"></span></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">نتیجه‏گیری: </span></span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">بر اساس نتایج مطالعه حاضر با این‏که در شیوع پیامدهای مادری تفاوتی بین دوران کووید-19 و قبل از آن دیده نشد، ولی پیامدهای نوزادی در دوران کووید-19 بیشتر از دوران قبل از آن بوده است که این موضوع بیانگر نیاز بیشتر برای انجام دقیق مراقبت‏های پره‏ناتال، آموزش پروتکل‏های بهداشتی، نظارت دقیق بر جنین حین و پس از زایمان برای کاهش عوارض و پیامدهای نوزادی در دوران کووید-19 است.</span></span></span></span><span dir="LTR" style="color:black"></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:120%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman","serif""><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">واژه­های کلیدی: </span></span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">پیامدهای مادری، پیامدهای نوزادی، همه­گیری </span></span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:120%"><span style="font-family:"B Nazanin""><span style="color:black">کووید-19</span></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Background and Objectives:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Coronavirus disease increased concern about vulnerable groups of society including pregnant women and babies. This study was conducted in order to investigate maternal and neonatal outcomes in newborns admitted to Ali Ibn Abi Talib Hospital in Rafsanjan before and after the COVID-19 pandemic.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Materials and Methods: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">In this cross-sectional study, 337 infants admitted to the hospital in the first 3 months of 2019 (before the start of the COVID-19 pandemic) and 194 infants admitted in the first 3 months of 2020 (after the start of the COVID-19 pandemic) were included. Demographic characteristics and maternal and neonatal complications were extracted from the files and analyzed by independent two-sample t-test and chi-square test.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Results: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">The Apgar scores of the first and fifth minutes had significantly decreased during the COVID-19 pandemic</span></span></span> <span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">(p<0.001), while infant death (p=0.003) and asphyxia at birth (p<0.001) had significantly increased. The frequency of premature rupture of fetal membranes, pre-eclampsia, eclampsia, and diabetes in the pregnant mothers before and after the pandemic were not statistically significant (p>0.05).</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Conclusion:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> According to the results of the present study, although there was no difference in the prevalence of maternal outcomes between the period of COVID-19 and before, but the outcomes of newborns during the period of COVID-19 were more than before, which indicates the need for more careful prenatal care, health protocols training, and careful monitoring of the fetus during and after delivery to reduce neonatal complications and outcomes during the COVID-19.</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Keywords: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Maternal outcomes, Neonatal outcomes, COVID-19 pandemic</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Funding:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> This study did not have any funds</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">.</span></span></span><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Conflict of interest:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> None declared</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">.</span></span></span><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Ethical considerations: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">The Ethics Committee of Rafsanjan University of Medical Sciences approved the study (IR.RUMS.REC.1401.075).</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Authors’ contributions</span></span></span></b><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">:</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span> <b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Conceptualization: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Sedigheh Salmeei<b> </b></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Methodology: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Mina Barzegar</span></span></span><b> </b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Data collection: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Mina Barzegar</span></span></span><b> </b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Formal analysis: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Zahra Kamiab, Mina Barzegar</span></span></span> <span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Supervision: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Sedigheh Salmeei, Zahra Kamiab</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Project administration: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Sedigheh Salmeei</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span dir="RTL" lang="AR-SA" style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">-</span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black"> Writing - original draft: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Mina Barzegar</span></span></span></span></span></span></span></span><br>
<span style="font-size:10pt"><span style="line-height:130%"><span style="tab-stops:-45.0pt"><span style="text-autospace:none"><span style="font-family:"Times New Roman","serif""><b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">- Writing - review and editing: </span></span></span></b><span style="font-size:9.0pt"><span style="line-height:130%"><span style="color:black">Mina Barzegar, Sedigheh Salmeei, Zahra Kamiab</span></span></span><b><span style="font-size:8.0pt"><span style="line-height:130%"><span style="color:black"></span></span></span></b></span></span></span></span></span><br>
پیامدهای مادری, پیامدهای نوزادی, همهگیری کووید-19
Maternal outcomes, Neonatal outcomes, COVID-19 pandemic
157
168
http://journal.rums.ac.ir/browse.php?a_code=A-10-6586-2&slc_lang=fa&sid=1
Mina
Barzegar
مینا
برزگر
6900319475328460057398
0009-0007-3221-6358
No
Rafsanjan University of Medical Sciences
دانشگاه علوم پزشکی رفسنجان
Sedigheh
Salmei
صدیقه
سلمه ای
6900319475328460057399
0009-0008-9947-0833
Yes
Rafsanjan University of Medical Sciences
دانشگاه علوم پزشکی رفسنجان
Zahra
kamiab
زهرا
کامیاب
6900319475328460057400
6900319475328460057400
No
Rafsanjan University of Medical Sciences
دانشگاه علوم پزشکی رفسنجان