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URL: http://journal.rums.ac.ir/article-1-2189-en.html
Survey of the Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain in Laparoscopic Cholecystectomy Surgery
H. Sattari[1], M.A. Haghbin1, M. Etminan[2], A. Dehghani[3]
Received: 10/06/2014 Sent for Revision: 09/07/2014 Received Revised Manuscript: 29/10/2014 Accepted: 16/11/2014
Background and Objective: Despite applying new drugs and techniques, many patients experience moderate to severe pain after surgery. Our goal in this study was to determine the effect of intravenous (IV) lidocaine infusion on postoperative pain in laparoscopic cholecystectomy surgery.
Materials and Methods: In this double-blind clinical trial a total of 70 candidates for laparoscopic cholecystectomy surgery were randomly selected and divided into two groups. With the same condition, in the case group before surgery , 1.5 mg/kg lidocaein 2% and then infusion of 2 mg/kg/h lidocaein 2% and the same volume of normal saline for control group was injected. Systolic and diastolic blood pressures, heart rate, analgesic score according to Visual Analog scale (VAS) were recorded and the data analyzed by mann-whitney and chi-square tests.
Results: Pain intensity according to VAS after postoperation was significantly lower in case group( 1.25±2.88) by comparison with control (6.00±3.84), (p= 0.001). Analgesics consumption in suppository from and IV was significantly lower than the case group (p<0.05).
Conclusion: Results wereshown lidocaine infusion can decrease pain intensity and analgesics consumption after laparoscopic cholecystectomy surgery.
Key words: Intravenous infusion, Lidocaine , Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Funding: This research was funded by Kerman University of Medical Sciences.
Conflict of interest: None declared.
Ethical Approval: The Ethics Committee of Kerman University of Medical Sciences approved the study.
How to cite this article: Sattari H, Haghbin MA, Etminan M, Dehghani A. Survey the Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain in Laparoscopic Cholecystectomy Surgery. J RafsanjanUniv Med Sci 2015; 13(10): 937-48. [Farsi]
[1]- Assistant Prof., Dept. of Anesthesia, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
[2]- Assistant of Anesthesia, Dept. of Anesthesia, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
(Corresponding Author) Tel: (034) 33222270, Fax:(034)33222270, E-mail:metminan@gmail.com
[3]- MSc in Biostatistics, Clinical Research Unit, Afzalipour hospital, Kerman University of Medical Sciences, Kerman, Iran
Received: 2014/06/9 | Accepted: 2015/01/4 | Published: 2015/02/21
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