Volume 13, Issue 10 (2-2015)                   JRUMS 2015, 13(10): 937-948 | Back to browse issues page

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Sattari H, Haghbin M, Etminan M, Dehghani A. Survey of the Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain in Laparoscopic Cholecystectomy Surgery. JRUMS. 2015; 13 (10) :937-948
URL: http://journal.rums.ac.ir/article-1-2189-en.html
Department of Anesthesia, School of medical, Kerman University of medical science
Abstract:   (6218 Views)

Background and Objective: Despite applying new drugs and techniques, many patients experience moderate to severe pain after surgery. Our goal in this study was to determine the effect of intravenous (IV) lidocaine infusion on postoperative pain in laparoscopic cholecystectomy surgery.

Materials and Methods: In this double-blind clinical trial a total of 70 candidates for laparoscopic cholecystectomy surgery were randomly selected and divided into two groups. With the same condition, in the case group before surgery , 1.5 mg/kg lidocaein 2% and then infusion of 2 mg/kg/h lidocaein 2% and the same volume of normal saline for control group was injected. Systolic and diastolic blood pressures, heart rate, analgesic score according to Visual Analog scale (VAS) were recorded and the data analyzed by mann-whitney and chi-square tests.

Results: Pain intensity according to VAS after postoperation was significantly lower in case group( 1.25±2.88) by comparison with control (6.00±3.84), (p= 0.001). Analgesics consumption in suppository from and IV was significantly lower than the case group (p<0.05).

Conclusion: Results wereshown lidocaine infusion can decrease pain intensity and analgesics consumption after laparoscopic cholecystectomy surgery.

Key words: Intravenous infusion, Lidocaine , Postoperative Pain, Laparoscopic Cholecystectomy Surgery


Funding: This research was funded by Kerman University of Medical Sciences.

Conflict of interest: None declared.

Ethical Approval: The Ethics Committee of Kerman University of Medical Sciences approved the study.


How to cite this article: Sattari H, Haghbin MA, Etminan M, Dehghani A. Survey the Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain in Laparoscopic Cholecystectomy Surgery. J RafsanjanUniv Med Sci 2015 13(10): 937-48. [Farsi]

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Type of Study: Review Article | Subject: Anesthesiology
Received: 2014/06/9 | Accepted: 2015/01/4 | Published: 2015/02/21

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