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, NJ. Gerey , Z. Arekhi , N. Seyedghasemi , Z. Abbasinejad , H. Gheleshli , S. Nademi , F. Niknejad
Antifungal Activity of Kiwi Alcoholic Extract on Saprophytes and Dermatophytes Fungi
I. Gharanjic [1], NJ. Gerey1, Z. Arekhi1, N. Seyedghasemi [2], Z. Abbasinejad [3], H. Gheleshli 1, S. Nademi1, F. Niknejad [4]
Received: 27/12/2014 Sent for Revision: 27/01/2015 Received Revised Manuscript: 08/03/2015 Accepted: 08/04/2015
Background and Objective: There are a few reports of antifungal activity of kiwi extract. This study was designed to investigate the antifungal activity of kiwi alcoholic extract on Saprophytes and Trichophyton mentagrophytes and Dermatophytes for the first time in Iran.
Materials and Methods:A Fungal suspension containing 1×105 CFU/mL of conidia and yeasty cells from 9 selected fungi was prepared in normal salin with tween 80 (0.5%). In order to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of kiwi alcoholic extract, serial dilution of kiwi extract was prepared to Sabouraud Dextrose Broth medium. Candida spp and Aspergillus spp cultures were incubated at 30 and 25°C for 24-72 hours, respectively. Data was analyzed with chi-square and analysis of variance test and p<0.05 considered as significance level.
Results: The ranges of percentage reduction in growth of dermatophyte and saprophytes were seen at a concentration of 10 and 20% in 24 and 48 hours, respectively. There were no significant differences between two groups (p>0.05).
Conclusion: This study showed that alcoholic extract of kiwi fruit has anti-fungal property and this feature may depend on the type of fungus.
Key words: Antifungal activity, Trichophyton mentagrophyte, Saprophyte Fungi, Kiwi
Funding: This research was funded by Golestan University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Golestan University of Medical Sciences approved the study.
How to cite this article: Gharanjic I, Gerey NJ, Arekhi Z, Seyedghasemi N, Abbasinejad Z, Gheleshli H, Nademi S, Niknejad F. Antifungal Activity of Kiwi Alcoholic Extract on Saprophytes and Dermatophytes Fungi. J RafsanjanUniv Med Sci 2015; 14(2): 151-60 [Farsi]
[1]- Student Research Committee, Golestan University of Medical sciences, Golestan, Iran
[2]- Faculty of Health, Golestan University of Medical Sciences, Golestan, Iran
[3]- Paramedicine Faculty, Golestan University of Medical sciences, Golestan, Iran
[4]- Assistant Prof., Laboratory Research Center, Golestan University of Medical sciences, Golestan, Iran
(Corresponding Author) Tel: (017) 32421664, Fax: (017) 32423630, E-mail: niknejad@goums.ac.ir
Received: 2014/12/24 | Accepted: 2015/04/8 | Published: 2015/05/13
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