Volume 16, Issue 8 (11-2017)
JRUMS 2017, 16(8): 769-788 |
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Razavinia F, Fazeli R, Tatari F, Pahlavan F, Tehranian N. The Role of Orexin A During Pregnancy and Lactation and Sudden Infant Death (SIDS) : A Systematic Review. JRUMS 2017; 16 (8) :769-788
URL: http://journal.rums.ac.ir/article-1-3798-en.html
URL: http://journal.rums.ac.ir/article-1-3798-en.html
tarbiatmodares univercity
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The Role of Orexin A During Pregnancy and Lactation and Sudden Infant Death (SIDS) : A Systematic Review
F. Razavinia[1], R. Fazeli1, F. Tatari1, F. Pahlavan1, N. Tehranian[2]
Received: 06/06/2017 Sent for Revision: 26/09/2017 Received Revised Manuscript: 09/10/2017 Accepted: 15/10/2017
Background and Objectives: Adipose tissue plays a role in releasing hormones including orexin, that regulates energy metabolism, nutrition, body weight, control system, autonomic, sleep, insulin sensitivity, breathing, drug addiction ,and reproductive axis. The pregnancy is associated with a series of metabolic changes that provide energy and nutrients for mother and fetus. Orexin increases insulin sensitivity and reduces diabetes and metabolism and increases energy expenditure and development of the fetus and newborn. This review aimed to summarize the studies related to orexin A ,normal and complicated pregnancy, lactation ,and sudden infant death (SID).
Materials and Methods: In this study, 320 articles were found through electronic search in Pubmed, Google, Google Scholar, Yahoo, Iran Medex, Science Direct, and SID databases during 1998 to 2016 and 13 articles were finally examined.
Results: The results showed that orexin A in the placenta plays an important role in the regulation of energy metabolism during pregnancy and AF volume and its reduction probably causes idiopathic polyhydramnius and increases the risk of gestational diabetes resolutions. And its reduction after delivery increases prolactin and lactation. Orexin A reduction in brain stem is associated with sleep disorders that causes sudden infant death to occur.
Conclusion: The study showed that, orexin plays a role in improving insulin resistance and sets the sleep cycle, fetal and infant growth , uncomplicated pregnancy ,and lactation.
Key word: Oraxin A , Pregnancy , SIDS , Energy metabolism, Lactation
Funding: This research was funded by Authors.
Conflict of interest: None declared.
Ethical approval: None declared.
How to cite this article: Razavinia F, Fazeli R, Tatari F, Pahlavan F , Tehranian N. The Role of Orexin A During Pregnancy and Lactation and Sudden Infant Death (SIDS) : A Systematic Review. J Rafsanjan Univ Med Sci 2017; 16(8): 769-88. [Farsi]
[1]- MSc Student , Dept. of Midwifery & Reproductive Health , Tarbiat Modares Univercity of Medical Sciences, Tehran, Iran
F. Razavinia[1], R. Fazeli1, F. Tatari1, F. Pahlavan1, N. Tehranian[2]
Received: 06/06/2017 Sent for Revision: 26/09/2017 Received Revised Manuscript: 09/10/2017 Accepted: 15/10/2017
Background and Objectives: Adipose tissue plays a role in releasing hormones including orexin, that regulates energy metabolism, nutrition, body weight, control system, autonomic, sleep, insulin sensitivity, breathing, drug addiction ,and reproductive axis. The pregnancy is associated with a series of metabolic changes that provide energy and nutrients for mother and fetus. Orexin increases insulin sensitivity and reduces diabetes and metabolism and increases energy expenditure and development of the fetus and newborn. This review aimed to summarize the studies related to orexin A ,normal and complicated pregnancy, lactation ,and sudden infant death (SID).
Materials and Methods: In this study, 320 articles were found through electronic search in Pubmed, Google, Google Scholar, Yahoo, Iran Medex, Science Direct, and SID databases during 1998 to 2016 and 13 articles were finally examined.
Results: The results showed that orexin A in the placenta plays an important role in the regulation of energy metabolism during pregnancy and AF volume and its reduction probably causes idiopathic polyhydramnius and increases the risk of gestational diabetes resolutions. And its reduction after delivery increases prolactin and lactation. Orexin A reduction in brain stem is associated with sleep disorders that causes sudden infant death to occur.
Conclusion: The study showed that, orexin plays a role in improving insulin resistance and sets the sleep cycle, fetal and infant growth , uncomplicated pregnancy ,and lactation.
Key word: Oraxin A , Pregnancy , SIDS , Energy metabolism, Lactation
Funding: This research was funded by Authors.
Conflict of interest: None declared.
Ethical approval: None declared.
How to cite this article: Razavinia F, Fazeli R, Tatari F, Pahlavan F , Tehranian N. The Role of Orexin A During Pregnancy and Lactation and Sudden Infant Death (SIDS) : A Systematic Review. J Rafsanjan Univ Med Sci 2017; 16(8): 769-88. [Farsi]
[2]- Assistant Prof.Dept. of Midwifery & Reproductive Health, Tarbiat Modares Univercity of Medical Sciences, Tehran, Iran
(Corresponding Author) Tell: (021)82883589, Fax: (021) 88006534, Email: n_tehranian@yahoo.com
(Corresponding Author) Tell: (021)82883589, Fax: (021) 88006534, Email: n_tehranian@yahoo.com
Type of Study: Review Article |
Subject:
Gynecology
Received: 2017/05/7 | Accepted: 2017/10/15 | Published: 2017/12/16
Received: 2017/05/7 | Accepted: 2017/10/15 | Published: 2017/12/16
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