Journal of Rafsanjan University of Medical Sciences

---

  Background and Objectives: Human resource s as the most important asset of each organization determine how other resources are used and cause organization's achievement. Job satisfaction is an important part of employees' life which affects their physical and mental health, satisfaction with life, their productivity and performance, commitment to work and quality of care they provide. The purpose of this study was to examine job satisfaction among employees of Azna district health network.

  Materials and Methods: This is a cross-sectional survey conducted with participation of all workers of Azna district health network. Out of 320 distributed questionnaires 265 valid responses were returned. The data collection tool was a researcher-developed questionnaire that measured eight domains of job satisfaction. Data were analyzed with descriptive and analytical statistical tests (X², Mann-Whitney, Kruskal Wallis)

  Results: The average of overall job satisfaction score was 2.90 on a scale from 1 (very dissatisfied) to 5 (very satisfied), that indicate a moderate level of job satisfaction. Respondents were least satisfied with fairness of pay and benefits (1.97) and training and career advancement (2.58) as compared with the nature of job (3.73) and work climate (3.58). Gender, martial status and educational level were significant factors in determining job satisfaction.

  Conclusion : Identifying job satisfaction determinants can help policy makers and human resource managers to develop effective strategies for improving productivity of this valuable resource which matters in achieving health system goals and sustainable development of the country.

  Key words: Job Satisfaction, Employees, District health network, Azna

  

  Funding: This study had no source of funding.

  Conflict of interest: Non declared.

  Ethical approval: The Ethics Committee of Shahid Beheshti University of Medical Sciences approved the study.

 

  How to cite this article : Danesh kohan A, Alipour M, Ahmadi N, Sajjadi F, Sari M . Job Satisfaction Among Employees of Azna District Health Network, 2009. J Rafsanjan Univ Med Sci 2013 12(7): 505-18. [Farsi ]

---

Background and Objectives: Cancer is the most important cause of death worldwide. Natural products and derivatives of medicinal plants can play an important role to cure cancer. The aim of this study was to evaluate the cytotoxic effect of ethanolic extracts of Pistacia Khinjuk leaf on Hela and MCF-7 cell lines.

Materials and Methods: In this laboratory study, ethanolic extract of Pistacia Khinjuk leaves was prepared by using maceration method and its cytotoxic effect on Hela and MCF-7 cell lines was investigated. Hela and MCF-7 cell lines were treated with various concentrations of extract (0.156-10.0 mg/ml) for 72 hours and growth inhibition was assayed using MTT )Methy Thiazol Tetrazolium) test. The optical density of the coloured solution was quantified at 570 nm wavelengths by an ELISA Reader. Data were analyzed using one-way ANOVA and Dunnett's post-test.

Results: The results showed that different concentrations of ethanolic extract significantly reduced the growth of Hela and MCF-7 cell lines compared to the control group after 72 hours (P< 0.05). The highest percentages of growth inhibition at concentration of 0.156 mg/ml were 81.33% and 76.76% and the IC₅₀ values were 2.41 and 2.40 mg/ml for Hela and MCF-7 cell lines, respectively.

Conclusion: The findings of the present study showed that the ethanolic extract of Pistacia Khinjuk leaf possessed inhibitory effect on Hela and MCF-7 cell lines. In order to find the underlying mechanism of this activity, further research should be carried out.

Key words: Cytotoxicity, Ethanolic extract, Pistacia Khinjuk, Hela and MCF-7 cell lines

Funding: This research was funded by Islamic Azad University, Qaemshahr Branch.

Conflict of interest: None declared.

Ethical approval: This article does not need permission from the Ethics Committee because the information in this article was derived from a non-animal research.

How to cite this article: Seyedalipour B, Pourakbar E, Taravati A. The Cytotoxic Effect of Ethanolic Extract of Pistacia Khinjuk Leaf Aganist HeLa and MCF-7 cancerous Cell Lines. J RafsanjanUniv Med Sci 2016; 14(11): 939-52. [Farsi]

---

Background and Objectives: Postpartum depression is a mood disorder that can occur within a year after delivery and influence the mother and even the baby. Because antidepressant medications have numerous side effects, they should be used cautiously especially in nursing mothers. Vitamin B6 is involved in the synthesis of several neurotransmitters and also no side effects have been reported for its use. Thus, this study aimed to investigate the effect of vitamin B6 on postpartum depression in female mice models.
Materials and Methods: In this experimental study, some adult female NMARI mice (25-30 gr) were divided into 7 groups (n=8) including the control, sham (receiving solvent), untreated depressed group (only receiving progesterone), and four depressed groups of which three were treated with a dose of vitamin B6 (25, 50, and 100 The mice getting 5 mg/kg/bw progesterone for 5 days were intraperitoneally mg/kg/bw) and one was treated for 8 days with a dose of 25 mg/kg/bw vitamin B6. The mice getting 5 mg/kg/bw of progesterone for 5 days were intraperitoneally (ip) depressed. The control group did not receive any drug or solvent. Depression was assessed using the forced swim test on the eighth day. The data were analyzed by using one-way ANOVA followed by LSD (least significant difference) post hoc test.
Results: Vitamin B6 prescribed in single doses of 50 and 100 (mg/kg/bw) (P<0.001), and also in a dose of 25 (mg/kg/bw) for 8 days (P=0.016) caused a significant reduction in the immobilization time in the depressed mice which had undergone the forced swim test, compared to the untreated depressed mice.
Conclusion: Prescription of progesterone promoted immobilization-induced depression in the mice. Vitamin B6 reduced the time of immobility in the forced swimming test. These findings can be used to show the effects of vitamin B6 in the reduction of postpartum depression.
Key words: Postpartum depression, Progesterone, Mice, Vitamin B6
 
Funding: This research was funded by Islamic Azad University of Izeh Branch, Iran.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Islamic Azad University approved the study (IR.IAU.1395.03).
 
How to cite this article: Sargholi F, Valipour-Chahardahcharic S. The Effect of Intraperitoneal Administration of Vitamin B6 During and Post Pregnancy on the Model of Postpartum Depression in Adult Female Mice. J Rafsanjan Univ Med Sci 2017; 16(7): 623-32. [Farsi]     
 

---

 
Background and Objectives: β-tubulin protein is the protein that has a key role in plasticity and neurogenesis in the mature neurons. On the other hand, endurance training is effective in neuron life and lifespan. The present study aimed to investigate the effect of 20 days swimming training on class III β-tubulin and the number of ganglion cells in DRG of Wistar male rats.
Materials and Methods: In this experimental study, 16 male Wistar rats (healthy) weighing 200-250 gr were randomly divided into control and exercise training groups. The exercise training group performed a swimming training program for 20 days, the control group did not participate in any activity. In the following, the ganglionic cells population and β-tubulin protein level in the posterior root of the spinal cord was measured by Cresyl violet staining method and immunofluorescence, respectively. Finally, data were analyzed using the independent t-test.
Results: The results showed that swimming activity significantly (p=0.0001) increased beta-tubulin protein in the experimental group. Also the a significant increase in the ganglion cells population was observed in the spinal cord posterior root of the experimental group compared to the control group (p=0.0001).
Conclusion: Swimming endurance activity may have a protective and restorative effect by increasing neurogenesis on dorsal root ganglion neurons.
Key word: Beta-tubulin, Ganglion, Spinal dorsal root, Swimming, Wistar male rats
Funding: This research was funded by Lorestan University.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Lorestan University approved the study (13971121122).
 
How to cite this article: Mardani Pour Z Fathi M, Valipour Dehnou V, Gorgin Keraji Z. The Effect of Swimming Training on Ganglionic Cells Population and Class III Beta-Tubulin Protein in Dorsal Root Ganglion of Wistar Male Rats: An Experimental Study. J Rafsanjan Univ Med Sci 2020; 18 (12[11] ): 1143-54. [Farsi]

---

Background and Objectives: In food stores, some unsanitary behaviors can be a factor in the transmission of coronavirus. Therefore, the present study was conducted with the aim of determining the status of compliance with health protocols in preventing the transmission of the coronavirus in food stores in Babol.
Materials and Methods: The present descriptive study was conducted among 214 customers of food stores in Babol. Information was collected through interviews using a valid and reliable questionnaire. Data analysis was performed using chi-square test.
Results: Two people (0.9 percent), 44 people (20.6 percent), and 168 people (78.5 percent) of customers said that compliance with health protocols in food stores was poor, average, and good, respectively. 40.7% of the customers (87 subjects) were completely satisfied with the hygiene measures in the store, and 31.8% (68 subjects) reported that they pay attention to the brand of the grocery store for shopping.
Conclusion: The results showed that the health condition of the investigated food stores was favorable. Health recommendations can be helpful.
Key words: Coronavirus, Health protocols, Food store, Babol

Funding: This study was funded by the Deputy of Research and Technology of the Babol University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Babol University of Medical Sciences approved the study (IR.MUBABOL.HRI.REC.1401.017).

How to cite this article: Faraji Hossein, Aghalari Zahra, Jafarian Somayeh, Lelahi Davood, Valipour Mortaza. Examining the Status of Compliance with Health Protocols in Preventing the Transmission of the Coronavirus in the Food Stores of Babol in 2022: A Short Report. J Rafsanjan Univ Med Sci 2023; 22 (2): 211-20. [Farsi]