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The Calculation of Absorbed Dose from 131I Radioactive Source in Thyroid Using MCNP Code for Spherical and Cylindrical Fields
Aa. Mowlavi, Ar. Binesh,
Volume 5, Issue 1 (6-2006)
Abstract

  The Calculation of Absorbed Dose from 131I Radioactive Source in Thyroid Using MCNP Code for Spherical and Cylindrical Fields

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  AA. Mowlavi PhD [1] , AR. Binesh MSc [2]

Background and Objective: 131 I radionuclide has been widely used for treatment of thyroid cancer and hyperactivity. In this regard the accurate calculation of absorbed dose in thyroid gland and other organs is important. Materials and Methods: In this study, according to MIRD method, MCNP code was used for calculation of absorbed dose of 131I radioactive sources in any thyroid with specific mass and size. Results: The results of two different geometries spherical and cylindrical shapes for each lobe of thyroid were compared. The results show when the thyroid mass increase from 20gr to 70gr, the absorbed dose per one disintegration increases 4.2%.

  Conclusion: These results firstly indicate that instead of using the total mass of thyroid in iodine therapy, it would be better to use the calculated active mass of thyroid. Secondly, the variation of absorbed dose per disintegration of 131I should be considered for the measurement of source activity in treatment of thyroid hyperactivity or cancer.

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  Key words: Absorbed dose 131I radionuclide MIRD method MCNP code Thyroid gland


  [1] - Assistant Professor, Dept. of Physics, School of Sciences, Tarbiat Moallem University of Sabzevar,SZabzevar

 �(Corresponding Author) Tel: (0 571) 4410105, Fax: (0 571) 4411161, E-mail: amowlavi@sttu.ac.ir

  [2] - Academic Member, Dept. of Physics, Payam-Nour University of Fariman, Fariman


Primary Pulmonary Hodgkin’s Disease (Case Report)
A.h. Halavani, F. Binesh,
Volume 8, Issue 3 (12-2009)
Abstract
Background and Objectives: Lung involvement in Hodgkin's disease is usually associated with nodal involvement and is due to direct extension from mediastinal nodes. Primary pulmonary Hodgkin’s disease is a rare disease. This disease occurs most frequently in the older women.
Case Report: The present case was a 54-year-old woman who was presented with fever, dry cough and weight loss since the last three months. There was no evidence of hepatosplenomegaly and peripheral lymphadenopathy. Radiological investigations revealed bilateral pulmonary nodular lesions but no mediastinal lymphadenopathy. Cyto-pathology assessment of the sample which was taken based on bronchoscopic and CT results did not help with diagnosis of the disease. As a last resort, open lung biopsy was done and a diagnosis of Hodgkin's disease was made. The final diagnosis was primary pulmonary Hodgkin's disease.
Conclusion: Although primary pulmonary Hodgkin's is a rare disease, it should be considered as one of the causes of bilateral pulmonary nodular lesions.
 
Key words: Hodgkin, Lymphoma, Pulmonary, Primary
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