I. Gharanjic, Nj. Gerey, Z. Arekhi, N. Seyedghasemi , Z. Abbasinejad, H. Gheleshli, S. Nademi, F. Niknejad,
Volume 14, Issue 2 (5-2015)
Background and Objective: There are a few
reports of antifungal activity of kiwi extract. This study was designed to
investigate the antifungal activity of kiwi
alcoholic extract on Saprophytes and Trichophyton mentagrophytes and Dermatophytes for the first time in Iran.
Materials
and Methods:A Fungal suspension containing 1×105 CFU/mL of conidia and yeasty cells from 9 selected
fungi was prepared in normal salin with tween 80 (0.5%). In order to determine
the minimum inhibitory concentration (MIC) and
minimum fungicidal concentration (MFC) of kiwi alcoholic extract, serial
dilution of kiwi extract was prepared to Sabouraud Dextrose Broth medium.
Candida spp and Aspergillus spp cultures were incubated at 30 and 25°C for
24-72 hours, respectively. Data was analyzed with chi-square and analysis of
variance test and p<0.05 considered as significance level.
Results:
The ranges of percentage reduction in growth of dermatophyte
and saprophytes were seen at a concentration of 10 and
20% in 24 and
48 hours, respectively. There were no significant differences between two groups (p>0.05).
Conclusion:
This study showed that alcoholic extract of kiwi fruit has anti-fungal property
and this feature may depend on the type of fungus.
Key words: Antifungal activity, Trichophyton mentagrophyte, Saprophyte Fungi, Kiwi
Funding: This research was
funded by Golestan University of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee
of Golestan University of Medical Sciences approved the study.
How
to cite this article: Gharanjic I, Gerey NJ, Arekhi Z,
Seyedghasemi N, Abbasinejad Z, Gheleshli H, Nademi
S, Niknejad F. Antifungal Activity of Kiwi Alcoholic Extract on Saprophytes and
Dermatophytes Fungi. J
RafsanjanUniv Med Sci 2015 14(2): 151-60 [Farsi]
