Background and Objectives : RUNX2 is the most specific transcription factor in osteoblastic differentiation of MSCs. In this research, RUNX2 expression was quantified in MSCs differentiated by osteogenic differentiation medium (ODM) and zoledronic acid (ZA).
Materials and Methods: In this experimental study, hMSCs were treated by osteogenic differentiation medium and ZA. RNA extraction was carried out from both osteoblastic differentiated cells in the first, second and third weeks of differentiation, and also from undifferentiated MSCs. RUNX2 expression was quantified by quantitative Real Time-PCR.
Results: Gene expression of RUNX2 in the first, second and third weeks of osteogenic differentiation by ODM compared to undifferentiated MSCs showed 1.76±0.09-fold, 3.54±0.25-fold and 3.40±0.17-fold increase in expression, respectively. Zoledronic acid increased the expression of RUNX2 2.91±0.13-fold, 3.25±0.3-fold and 3.36±0.23-fold at the same time points, respectively. Comparison of RUNX2 expression by ODM (1.76±0.09-fold) and ZA (2.91±0.13-fold) in the first week of differentiation showed statistical differences (P<0.05). Whereas, RUNX2 expression by both ODM and ZA in the second and third weeks of differentiation were approximately equal.
Conclusion: RUNX2 expression was increased in osteoblastic differentiation by both ODM and ZA. However, it seems that ZA can cause more expression of RUNX2 in the first week of osteoblastic differentiation.
Key words: Mesenchymal Stem Cells, Differentiation Medium, Zoledronic Acid, RUNX2 Transcription Factor
Funding: This research was funded by Tarbiat Modares University.
Conflict of interest: None declared.
Ethical approved: The Ethics Committee of Tarbiat Modares University approved the study .
How to cite this article : Farshdousti Hagh M , Noruzinia M, Mortazavi Y, Soleimani M, Kaviani S, Mahmoodinia Maymand M . Comparison of Quantitative Expression of Runx2 in Mesenchymal Stem Cells (Mscs) Differentiated by Osteoblastic Differentiation Medium and Zoledronic Acid . J Rafsanjan Univ Med Scie 2012 11(4): 377-90. [Farsi]
Background and Objective: Today researchers consider
sports as one of the methods of reinforcing psychological parameters
development. The purpose of the present study was to compare
psychological well-being in the athlete and non-athlete (ordinary) students.
Materials and Methods: This was
a cross sectional study and the statistical population included all high school
students of Miyandoab city during 2012-2013 educational year. The statistical
sample of the research included 100 athlete student and 100 non-athlete student
who were selected through multistage cluster sampling. The participants
answered Ryff’s Psychological Well-being Scale (with 0.68 reliability). Data
were analyzed using independent two sample t-test and multivariate analysis of
variance (MANOVA).
Results: Results of t-test revealed
that psychological well-being of the athlete students (81.86±14.89) was significantly higher
than non-athlete students (76.13±9.22) (p<0.001). Results of
multivariate analysis of variances indicated that positive relationship with
others and purpose in life of athlete students (13.82±3.89 and
14.97±3.43,
respectively) were significantly
higher than non-athlete students (11.74±2.73 and 12.50±2.80 respectively) (p<0.001), while there
was no significant difference between the two groups in terms of
self-acceptance, environmental mastery, personal growth and autonomy (p>0.05).
Conclusions: The results revealed that
athlete students were in better position with regard to psychological
well-being, positive relationship with others and purpose in life
than non-athlete students.
Key words: Athlete, Non-athlete, Psychological well-being,
Students.
Funding: No grant has supported the
present study.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Islamic
Azad University, Ayatollah Amoli Branch approved the study.
How to cite this
article:
Ghasempour A, Jodat H, Soleimani M. A comparison of Psychological Well-Being
in athlete and Non-athlete Students . J Rafsanjan Univ Med Sci 2014 13(3): 193-204. [Farsi]
Background and Objectives: Breastfeeding is one of the key strategies for growth and survival of children, as it is rich in nutrients and better than any other food which ensures the growing child. However, statistics have reported that a lot of women avoid exclusive breastfeeding. The aim of this research was to assess the relationship between demographic factors, healthy family and social health with exclusive breastfeeding.
Materials and Methods: In this cross-sectional study, 375 women referred to Kashani hospital in the city of Jiroft in 2014 were selected via simple random sampling and completed demographic, healthy family and social health questionnaires. Independent t-test, chi-square test, Fisher's exact test and odds ratio (OR) were applied to analyze the data.
Results: The results showed that exclusive breastfeeding was more prevalent among women aged ≤30 years and housewives (p<0.001). With increasing the score of healthy families and its dimensions including communication with family, acceptance of death and separation, conflict resolution without stress, sensitivity to understanding each other, and building trust in people, the probability of exclusive breastfeeding by mothers increased (p<0.001). With increasing the score of social health and its dimensions including social acceptance, social actualization, social conformity and social participation, exclusive breastfeeding by mothers also increased (p<0.001).
Conclusion: With regard to the relationship between healthy family and social health with exclusive breastfeeding, health education about healthy family and social health may help to increase the rate of exclusive breastfeeding.
Key words: Healthy family, Social health, Breastfeeding, Jiroft
Funding: This research was funded by Imam Reza International University of Mashhad.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Imam Reza International University of Mashhad approved the study.
How to cite this article: Sanjari Sh, Mohammadi Soleimani MR, Khanjani N, Mohseni M, Ahmadi Tabatabaei SV. The Relationship Between Demographic Factors, Healthy Family and Social Health with Exclusive Breastfeeding in Women Referred to Kashani Hospital of Jiroft in 2014. J RafsanjanUniv Med Sci 2016; 15(2): 165-78. [Farsi]
Background and Objective: Vaginal infections are the most common infections that women are getting for primary reasons such as poor knowledge and practice. Change of knowledge and practice requires consideration of individual, environmental, and social factors that the PRECEDE-PROCEED model is widely used for this purpose. The aim of this study was to examine the effects of educational intervention based on the PRECEDE-PROCEED model on prevention of vaginal infections in Jiroft city women.
Materials and Methods: In this educational trial study, among three health centers in the city of Jiroft, two centers were selected by simple random sampling. So that one of the centers (Late Maleki center) was considered as the test group and the other center (number one center) was considered as the control. Of each center, 58 married women were selected by systematic random sampling method. Data gathering tool was a questionnaire constructed by the researcher based on the PRECEDE-PROCEED model. Educational interventions related to women infections were performed in 8 sessions for the intervention group. Data were collected before and two weeks after the intervention and analyzed using chi-square test, Wilcoxon and Mann-Whitney tests.
Results: The results showed that both intervention and control groups in terms of education, age, and employment status were matched (p>0.05) The mean difference (before and after) predisposing factors (knowledge and attitude), reinforcement factors, enabling factors, and behavior in the intervention and control groups were significantly different from each other (p<0.05), so that the intervention group increased significantly after the intervention.
Conclusion: Due to the effects of educational intervention through PRECEDE-PROCEED model to improve preventive behaviors of vaginal infection, providing educational programs for women may help them in the promotion of safe behavior about vaginal infections.
Key words: Prevention, Vaginal infection, PRECEDE-PROCEED model, Women
Funding: This research was funded by Imam Reza International University of Mashhad.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Imam Reza International University of Mashhad approved the study.
How to cite this article: Sanjari S, Mohammadi Soleimani MR. The impact of Education on the Prevention of Vaginal Infection Based on PRECEDE-PROCEED. J Rafsanjan Univ Med Sci 2017; 16(4): 338-52 [Farsi]
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