F. Ghorbanloo, A.a. Jafarnezhadgero, A. Valizadeh Orang,
Volume 19, Issue 7 (10-2020)
Abstract
Background and Objectives: Knee joint, like other joints in the body, is affected by defects, injuries and diseases. Genu valgum is one of the most common lower limb complications. The purpose of the present study was to determine the effects of corrective exercises using Thera-Band on components of ground reaction force in boy students with genu valgum during running.
Materials and Methods: The present study was a clinical trial. 24 male students (20-30 years old) were randomly divided into control and experimental groups. The present study was conducted at University of Mohaghegh Ardabili Health and Wellness Center in 2019. Corrective exercises were performed for 8 weeks using Thera-band for the experimental group. The control group did not receive any treatment intervention during this period. The ground reaction forces were recorded by a force plate. Data were analyzed using repeated measures ANOVA.
Results: The results of this study showed a significant difference in the time to peak in the vertical direction during the push off phase of the experimental group (5.17%) (p=0.030, d=0.589). In the experimental group, the other components of ground reaction forces did not demonstrate any significant effect during post-test than that in the pre-test (p>0.05).
Conclusion: The selected corrective exercises using the Thera-band were able to increase the time to peak of the vertical force during the push off phase during the post-test compared to the pre-test. This increase was probably due to the longer contact of foot with the surface, which reduces the amount of force applied to the foot.
Key words: Corrective exercises, Thera-band, Ground reaction forces, Genu valgum, Running
Funding: This study was funded by University of Mohaghegh Ardabili.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Ardabil University of Medical Sciences approved the study (IR-ARUMS-REC-1397-091).
How to cite this article: Ghorbanlou F, Jafarnezhadgero A A, Valizade Orang A. The Effect of Corrective Exercises Using Thera-Band on Components of Ground Reaction Force in Boy Students with Genu Valgum during Running: A Clinical Trial Study. J Rafsanjan Univ Med Sci 2020; 19 (7): 661-76. [Farsi]
Maryam Gholizadeh, Akbar Hajizadeh Moghaddam, Farhad Valizadehgan, Sedigheh Khanjani Jelodar,
Volume 22, Issue 6 (10-2023)
Abstract
Background and Objectives: Ethanol has shown strong neurodegenerative consequences in brain that are associated with oxidative stress. The aim of this study was to investigate the effects of silymarin on oxidative stress, anxiety, and learning disorder induced by ethanol in rats.
Materials and Methods: In this experimental study, 35 male Wistar rats with 200gr average weight were divided into five groups. The control group and four groups that received 4 gr/kg ethanol for 14 days. Three treatment groups were treated with doses of 50, 100, and 150 mg/kg silymarin for 14 days, respectively. Cognitive impairment and anxiety were assessed. The average activity of catalase and superoxide dismutase enzymes and glutathione (GSH) level in the hippocampus were also assessed. Data were analyzed using one-way analysis of variance (ANOVA) and Turkey’s post hoc test.
Results: Ethanol consumption significantly decreased the discrimination index (p<0.001), the percentage of open arm time (%OAT) (p<0.001), and the percentage of open arm entry (%OAE) (p=0.007) compared to the control group. Also, it reduced the activity of antioxidants catalase (p<0.001), superoxide dismutase (p=0.002), and glutathione level (p<0.001) compared to the control group, while silymarin consumption with dose 150 mg/kg significantly increased the discrimination index, OAE (p=0.022), and OAT (p=0.023) compared to the ethanol group. Also, it increased antioxidant activity of catalase (p=0.008), superoxide dismutase (p=0.030), and glutathione (p<0.001) compared to the ethanol group.
Conclusion: Silymarin may protect the hippocampus against behavioral disorder induced by ethanol consumption by increasing the level of antioxidants.
Key words: Silymarin, Cognitive impairment, Oxidative stress, Anxiety, Hippocampus, Rat
Funding: This study was funded by Mazandaran University.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Mazandaran University approved the study (IR.UMZ.REC.1400.012).
How to cite this article: Gholizadeh Maryam, Hajizadeh Moghaddam Akbar, Valizadegan Farhad, Khanjani Jelodar Sedigheh Silymarin Antioxidant Effect on Ethanol-Induced Anxiety and Learning Impairments in Rats: An Experimental Study. J Rafsanjan Univ Med Sci 2023; 22 (6): 555-66. [Farsi]
Hadis Valizadeh, Shahram Mami, Homeira Soleimannejad, Zeinab Mihandoost,
Volume 24, Issue 2 (5-2025)
Abstract
Background and Objectives: Substance abuse is a disaster for individuals, their families, and society. Its increasing trend creates significant challenges for individuals and healthcare systems. Effective treatment strategies are essential to address these challenges. Therefore, the present study aimed to compare the effectiveness of metacognitive therapy and time perspective therapy on emotion regulation in individuals with substance use disorder.
Materials and Methods: This research was a quasi-experimental study with a pre-test, post-test, and follow-up design with a control group. The statistical population included all men with substance use disorder referred to addiction treatment centers in Kermanshah in 2024. Sixty individuals were selected via convenience sampling and randomly assigned to three groups (n=20 per group). The metacognitive group received 8 sessions, and the time perspective group received 6 sessions of intervention, while the control group received no intervention. Data were collected using the Difficulties in Emotion Regulation Scale by Gratz and Roemer (2004). The data was analyzed using two-way repeated measures ANOVA.
Results: The effect of the interventions on improving emotion regulation (F=959.50, p=0.001) in individuals with substance use disorder was significant, and these positive effects remained stable during the follow-up period. Additionally, there was a statistically significant difference between the treatment methods (p<0.001), with metacognitive therapy being more effective in regulating the emotions of these individuals (p<0.001).
Conclusion: Considering the impact of metacognitive therapy on emotion regulation in individuals with substance use disorder in the present study, more attention to providing training based on this intervention is recommended.
Keywords: Drug dependence, Emotion regulation, Metacognitive therapy, Time perspective therapy
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical considerations: The Ethics Committee of Azad University, Ilam Branch, approved the study (IR.IAU.ILAM.REC.1403.095).
Authors’ contributions:
- Conceptualization: Hadis Valizadeh
- Methodology: Hadis Valizadeh, Shahram Mami, Homeira Soleimannejad, Zeinab Mihandoost
- Data collection: Hadis Valizadeh, Shahram Mami, Homeira Soleimannejad, Zeinab Mihandoost
- Formal analysis: Hadis Valizadeh, Shahram Mami
- Supervision: Shahram Mami
- Project administration: Shahram Mami
- Writing - original draft: Hadis Valizadeh, Shahram Mami, Homeira Soleimannejad, Zeinab Mihandoost
- Writing - review & editing: Hadis Valizadeh, Shahram Mami, Homeira Soleimannejad, Zeinab Mihandoost