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Showing 5 results for Myocardial Infarction

, , , ,
Volume 1, Issue 4 (12-2002)
Abstract

Background: Ischemic heart  disease is one of the major causes of death in the developed countries. Coronary Artery Disease is common in Iran, and deaths related to this factor are increasing. This survey is a descriptive study to determine knowledge ,attitude and practice of Kerman population about prevention of MI. The sample included 600 people who were selected in several stages (cluster, randomized and systemic) from different parts of the city.
Materials and Methods:A questionnaire was used for collecting the data. For data analysis ANOVA, Kruskalwalis, X2and regression (pearson) were used .
Results: The results of this survey showed that most people,s knowledge was moderate and in women, and those with educational level above highschool (diploma) was more than others. In attitude, most of the people were impartial or had positive attiude. Women and people with hyprtention, had a higher level of knowledge than others. In the practice field, the responders didn,t have proper performance in most items. The practice of 41-50 year olds and older people, who had better education, history of MI, hyperlipidemia, diabetes mellitus and hypertansion was better thar the others in a number of aspects (P<0/05).
Conclusion: The results of this study indicated that the role of health service members is an important one in increasing the knowledge and prevention of MI.
 
Key Words: knowledge, Attitude, Practice, Kerman, Prevention, Myocardial infarction
H. Nough,
Volume 2, Issue 1 (6-2003)
Abstract

  Effect of Streptokinase on Liver Function in Patients with Acute Myocardial Infarction.

 

  H. Nough *

  Assistant Professor of Cardiology, Rafsanjan University of Medical Sciences and Health Services, Rafsanjan , Iran .

 

  Background: Streptokinase (SK) is used for thrombolytic therapy in patients with acute myocardial infarction (AMI) who have no contraindication to this drug. SK is the only thrombolytic agent currently available in Iran. Several side effects have been reported for SK, but there is not enough information on its effects on the liver function. There are only a few case reports of icterus and spontaneous liver rupture after SK therapy. Therefore this study was designed to evaluate the SK effects on liver function in patients with AMI.

  Materials and Methods: In this clinical trial we selected 68 patients (42 males, and 26 females with mean age of 56 ± 8 years) with AMI that were admitted to the CCU ward. 45 patients who had indication for SK therapy (SK group) received infusion of 1500000 U of SK during 1 hour and 23 patients with AMI that had contraindication for SK therapy in the control group did not receive this treatment. These two groups were matched for age, sex and drug prescription. In all of the patients, liver enzymes, (AST and ALT), bilirubin (direct and total) and alkaline phosphatase were measurad at admission, and 2, 7 and 30 days after that. Exclusion criterias were: history of liver disease, cardiogenic shock, heart failure, ages over 75 years and history of cerebrovascalur accident during the last 6 months. Significant P value was considered as p<0.05.

  Results: In the SK group 46.6% and in the control group 8.7% had elevated liver transaminases more than two folds of the normal level. 33.3% in the SK group versus 4.3% in the control group had elevated liver enzymes more than 3 folds of the baseline values on admission. These differences were significant by fisher exact test (P= 0.0071).

  Conclusion: We concluded that thrombolytic therapy with SK causes acute impairment of hepatic function without icterus and commonly seen elevated liver enzyme about 2-3 times of the normal levels.

 

  Keywords: Streptokinase, Liver Function, Myocardial Infarction, ALT, AST.

  * Corresponding author, tel: (0391) 8220001-6


R. Vazirinejad, A. Esmaeili Nadimi, Y. Parvaresh, M. Rezaeian,
Volume 11, Issue 3 (7-2012)
Abstract

 

  Background and Objectives : The effect of diseases on the quality of life (QOL) of patients is due to the resulting temporary or permanent disability among patients. In this study, the effect of the myocardial infarction on the (QOL) of patients was measured and compared to the general population of Rafsanjan in order to recognize the most important aspects of patients life affected by the disease.

  Material and Mthods: In this historical cohort study, a group of people who were matched based on age, gender, educational status, social class, living place, occupation and marital status in two different groups of MI (n=50) and healthy (n=50) people were studied. The level of quality of life was measured using SF-36 scale. Parametric (t-test) and non-parametric (Mann-Whitney U and X2 ) tests were used to compare groups where appropriate.

  Results Proportion of people with undesirable quality of life among patients group was significantly greater than this value among the other group (P=0.001). Relative risk showed that suffering from MI significantly increases the probability of undesirable quality of life among people as 2.7 times greater (95%CI= 1.2-6.0).

  Conclusion: Our findings showed that MI decreased the quality of life significantly. It seems that providing adequate interventions for most patients suffering from MI can improve the vital aspects of their lives.

  Key words: Quality of life, Myocardial Infarction, Relative risk, Attributable risk

  Funding: This research was funded by Rafsanjan University of Medical Sciences.

  Conflict of intrest: None declared.

  Ethical approval: The Ethics Comittee of Rafsanjan University of Medical Sciences, approved the study.

  

  How to cite this article : Vazirinejad R, Esmaeili Nadimi A, Parvaresh Y, Rezaeian M . A Survey on the Most Important Life Aspects of Patients Suffering from Myocardial Infarction In Rafsanjan: A Historical Cohort Study Assessing Quality of Life . J Rafsanjan Univ Med Scie 2012 11(3): 219-30. [Farsi]


Mohsen Mirzaei, Amir Rahnama, Fathemeh Esmaeiliyan, Hamid Bakhshi,
Volume 12, Issue 8 (10-2013)
Abstract

Background and Objective: Coronary artery disease (CAD) in young people shows a different clinical, angiographic and pathophysiologic behavior in comparison to older age patients. Lipoprotein a (LPa) as a risk factor has a role for CAD so its serum measurement can be valuable for detecting people dispose to this group of diseases. Materials and Methods: We did a cross-secotinal study on a 120 people in 4 equal groups (patients with myocardial infarction and normal population, more and less than 45 years old). The data collected according to clinical examination and results of serum LPa, LDL, HDL levels. Then, data analyzed using to descriptive and analytical statistical tests i.e. the t test. Results: LPa level in both groups of normal people was 28.53±3.39 and both group of patients was 47.88±5.12 mg/dl (p= 0.015). Average LPa level between both groups of women less than 45 age old, in control 44.40±4.66 and patients group 81.03±12.14 was significant (p= 0.004). This value was significant between both group of women more than 45 years old in control 24.95±3.07 and patients groups 34.73±2.84 too (p= 0.001). Average LPa level between men less than 45 years in control 17.38±1.94 and patients groups 31.11±2.73 (p= 0.010) and men more than 45 years, in control 27.2±3.91 and patients groups 53.62±6.01 (p= 0.007) that was significant. Conclusion: Our study showed remarkable LPa level in coronary artery disease patients. Key words: Coronary artery disease risk factors, Lipoprotein a, Premature myocardial infarction Funding: This research was funded by Rafsanjan University of Medical Science. Conflict of interest: None declared. Ethical approval: The Ethics Committee of Rafsanjan University of Medical Science, approved the study. How to cite this article: Mirzaei M, Rahnama A, Esmaeelian F, Bakhsh H. Serum Level of Lipoprotein a (LPa) in Patients with Premature Myocardial Infarction. J Rafsanjan Univ Med Sci 2013 12(8): 655-66. [Farsi]
Z. Kamiab, M. Mirzaei, S. Dabiran,
Volume 15, Issue 11 (2-2017)
Abstract

Background and Objective: Age increase is known as a risk factor for cardiovascular disease and acute  myocardial infarction (AMI), but younger women and men are also at risk. The aim of this study was to evaluate the age changes of first AMI and risk factors affecting the patients admitted to the cardiac care unit of Ali- ibn- Abi Talib  hospital in Rafsanjan during the years 2003 to 2012.

Materials and Methods: This cross-sectional study was conducted on 1247 records of patients with first AMI hospitalized during the years 2003 to 2012. The variables examined in this study included age, gender, smoking, family history of MI , history of diabetes, systolic and diastolic blood pressure, triglycerides, HDL (High-density lipoprotein), LDL (Low-density lipoprotein) and total cholesterol of blood levels as independent variables and age of first AMI as the dependent variable. Data were analyzed using independent two-sample t- test and multiple linear regression.

Results: The average age of first AMI in these patients was 60.54±14.00 years. During the years examined, the age of first AMI was significantly increased to 9 years (p= 0.001). Based on multiple linear regression model, the male sex (B= -3.48, p=0.003), smoking history (B= -5.10, P<0.001), positive family history (B=-5.13, p<0.001), and high blood triglyceride levels (B=-3.52, P<0.001) had significant effect on decreasing the age of first AMI.

Conclusion: Despite increasing the mean of age process of AMI in this study, screening people at high risk including men, people with smoking history, positive family history and hyperlipidemia in terms of prognostic factors of this disease can be useful in controlling its incidence among young people.

Key words: Myocardial infarction, Age, Risk factors, Rafsanjan

Funding: This research was funded by Tehran University of Medical Sciences.

Conflict of interest: None declared.

Ethical approval: The Ethics Committee of Tehran University of Medical Sciences approved the study.

How to cite this article: Kamiab Z, Mirzaei M, Dabiran S. The Pattern of Age Changes of First Acute Myocardial Infarction in Rafsanjan During 2003 to 2012: Has Age Decreased?. J Rafsanjan Univ Med Sci 2017; 15(10): 1015-26. [Farsi]



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