Background
and Objective: Studies indicated that
physical activity influences sleep
quality and inflammatory markers,
but not have been studied much the relationship between sleep quality and inflammatory markers caused
by physical activity. The aim of
the present study was to investigate the relationship between sleep quality with interleukin-1β and C - reactive protein in
active and non-active men.
Material and Methods: The present study is cross-sectional. Twenty-two healthy males aged 32-38 years
participated voluntarily in this study, and were divided into two non-active
(n=11) and active (n=11) groups. The non-active group were without sports history
and the active group had more than two years of moderate-intensity aerobic exercise history (moderate aerobic training 45 minutes/day, 3days/week). Fasting blood samples were taken from all subjects. Serum C-reactive protein and interleukin -1 beta was measured by ELISA method and Pittsburg Sleep Quality Index Questionnaire
(PSQI) was used to evaluate sleep quality. The research data were analyzed using the independent t test, Pearson’s
correlation coefficient and Multiple
Linear Regression.
Results: IL-1β (p=0.015) and CRP (p=0.043) concentrations under the effect of physical activity in the active group compared to the
non-active group showed a significant decrease. The Sleep Quality Index score
was significantly lower in the active group compared to non-active group (p=0.021). A Significant relationship was observed between sleep
quality score, IL-1β (r=0. 571, p=0. 033) and CRP (r=0. 613, p=0. 012) concentrations in active men.
Conclusion: The present study
demonstrates that there is a significant relationship
between sleep quality
with IL-1β and
CRP levels in active men so that it may improve sleep
quality by reduction in inflammatory
markers.
Key words: Inflammatory factors, Sleep quality, Physical activity
Funding: This research was
funded by personal costs.
Conflict of interest: None
declared.
Ethical approval: The
Ethics Committee of Urmia University approved the study.
How to cite this article: Tartibian B, Kamrani A, Yaghoobnezhad F,
Mohammad Amini S. Investigation of the Relationship between Sleep Quality
with Interlukin-1β and C -
Reaction protein in
Active and Non-Active Men. J RafsanjanUniv Med Sci 2014 13(2): 141-50 [Farsi]
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