Volume 12, Issue 6 (7-2013)
JRUMS 2013, 12(6): 461-474 |
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Antibacterial Effect of Ethanol Extract (Althaea Officinalis) on Streptococcus Pyogenes Compared with Prevalent Antibiotics In-Vitro. JRUMS 2013; 12 (6) :461-474
URL: http://journal.rums.ac.ir/article-1-5292-en.html
URL: http://journal.rums.ac.ir/article-1-5292-en.html
Abstract: (2306 Views)
Background and Objectives: Streptococcus Pyogenes causes Impetigo, Scarlet fever and Angina. Marsh mallow (Althaea officinalis) is one of medicinal plants in old medicine that has been used for curing the above diseases. Due to health problems related to antibiotics such as drug resistance and disease relapse, this study was conducted to investigate antibacterial activity of ethanol marshmallow root extracts collected from different regions of Iran.
Materials and Methods: In a laboratory study that was conducted in 2012, Roots of Althaea officinalis collected from regions Qom, Tehran, Yazd, Anar, Zarand, Esfahan, Arak, Naien, Mahan and Baft and then Extraction procedure was carried out by Maceration method with ethanol then Effect of Different extract concentrations and regions on bacterial growth were compared with one and two-way analysis of variance. Paired means comparison was performed using Duncan's method and MIC of extracts was determined.
Results: Ethanol root extracts had antibacterial activity and inhibition zone had logarithmic response with increase of extract concentration.The highest inhibition zone was in concentration of 200 mg/ml and concentration of 50 mg/ml of yazd extract had same as Penicillin effect.The extract from Yazd region had Minimum of MIC with maximum of antibacterial activity and the extract of Tehran region had Minimum antibacterial activity and there wasn’t any activity from Arak extract.
Conclusion: Results show the effect of extract concentration and region of plant growth on bacterial growth. Therefore, to achieve the best therapeutic effect these issues should be considered.
Key words: Old medicine, Root of Althaea officinalis, Ethanol extract, MIC, Antibiotic, Streptococcus Pyogenes.
Funding: This research was funded by International Center for Science, High Technology & Environmental Sciences of Kerman.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of International Center for Science, High Technology & Environmental Sciences of Kerman approved the study.
How to cite this article: Dehghan E, Dashti H, Baghizadeh A. Antibacterial Effect of Ethanol Extract (Althaea Officinalis) on Streptococcus Pyogenes Compared with Prevalent Antibiotics In-Vitro. J Rafsanjan Univ Med Scie 2013; 12(6): 461-74. [Farsi]
Materials and Methods: In a laboratory study that was conducted in 2012, Roots of Althaea officinalis collected from regions Qom, Tehran, Yazd, Anar, Zarand, Esfahan, Arak, Naien, Mahan and Baft and then Extraction procedure was carried out by Maceration method with ethanol then Effect of Different extract concentrations and regions on bacterial growth were compared with one and two-way analysis of variance. Paired means comparison was performed using Duncan's method and MIC of extracts was determined.
Results: Ethanol root extracts had antibacterial activity and inhibition zone had logarithmic response with increase of extract concentration.The highest inhibition zone was in concentration of 200 mg/ml and concentration of 50 mg/ml of yazd extract had same as Penicillin effect.The extract from Yazd region had Minimum of MIC with maximum of antibacterial activity and the extract of Tehran region had Minimum antibacterial activity and there wasn’t any activity from Arak extract.
Conclusion: Results show the effect of extract concentration and region of plant growth on bacterial growth. Therefore, to achieve the best therapeutic effect these issues should be considered.
Key words: Old medicine, Root of Althaea officinalis, Ethanol extract, MIC, Antibiotic, Streptococcus Pyogenes.
Funding: This research was funded by International Center for Science, High Technology & Environmental Sciences of Kerman.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of International Center for Science, High Technology & Environmental Sciences of Kerman approved the study.
How to cite this article: Dehghan E, Dashti H, Baghizadeh A. Antibacterial Effect of Ethanol Extract (Althaea Officinalis) on Streptococcus Pyogenes Compared with Prevalent Antibiotics In-Vitro. J Rafsanjan Univ Med Scie 2013; 12(6): 461-74. [Farsi]
Keywords: Old medicine, Root of Althaea officinalis, Ethanol extract, MIC, Antibiotic, Streptococcus Pyogenes.
Type of Study: Research |
Subject:
Environmental Health
Received: 2020/05/9 | Accepted: 2020/05/9 | Published: 2020/05/9
Received: 2020/05/9 | Accepted: 2020/05/9 | Published: 2020/05/9
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