Volume 9, Issue 2 (6-2010)
JRUMS 2010, 9(2): 107-116 |
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Assessment of Acquired Color Vision Impairment among the Workers Exposed to Mixed Organic Solvents in an Automobile Manufacturing Company. JRUMS 2010; 9 (2) :107-116
URL: http://journal.rums.ac.ir/article-1-5344-en.html
URL: http://journal.rums.ac.ir/article-1-5344-en.html
Abstract: (1903 Views)
Background and Objectives: Solvents are widely used in industries. Occupational exposure to organic solvents can lead to dysfunction of the nervous system. Since color-vision impairment can be a sensitive and early marker of neurotoxic damage, this study was designed to determine the influence of chronic occupational exposure to organic solvent mixtures on color vision.
Materials and Methods: This discriptive study was conducted in an automobile plant in 2008. Workers employed in the painting saloon were considered as exposed and workers in the assembly were used as non-exposed. A questionnaire containing required data of workers was administered. After considering exclusion criteria, color vision of 157 exposed workers was compared with 174 non-exposed worker, using X2 test.
Results: The percentage of acquired dyschromatopsia was 43% in the exposed group and 3.45% in the other group. The percentage of acquired dyschromatopsia exposed employees was significantly higher than that of the non-exposed subjects (OR = 21.95, CI = 9.16- 52.57) (p<0.001). Mean of the color-confusion index for exposed employees was significantly higher than that among the other subjects (1.32 and 1.02 respectively) (p<0.001). The logistic regression for color confusion index indicated that the color-confusion index was positively related to exposure to mixed organic solvents (p<0.001).
Conclusions: The results of this study suggested that chronic occupational exposure with mixture of organic solvents, in higher amounts of permissible levels, can cause acquired color vision defects.
Key words: Organic Solvent, Color Vision, Occupational Exposure
Funding: This study was supported by Iran Univrsity of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Iran Univrsity of Medical Sciences, approved the study.
Materials and Methods: This discriptive study was conducted in an automobile plant in 2008. Workers employed in the painting saloon were considered as exposed and workers in the assembly were used as non-exposed. A questionnaire containing required data of workers was administered. After considering exclusion criteria, color vision of 157 exposed workers was compared with 174 non-exposed worker, using X2 test.
Results: The percentage of acquired dyschromatopsia was 43% in the exposed group and 3.45% in the other group. The percentage of acquired dyschromatopsia exposed employees was significantly higher than that of the non-exposed subjects (OR = 21.95, CI = 9.16- 52.57) (p<0.001). Mean of the color-confusion index for exposed employees was significantly higher than that among the other subjects (1.32 and 1.02 respectively) (p<0.001). The logistic regression for color confusion index indicated that the color-confusion index was positively related to exposure to mixed organic solvents (p<0.001).
Conclusions: The results of this study suggested that chronic occupational exposure with mixture of organic solvents, in higher amounts of permissible levels, can cause acquired color vision defects.
Key words: Organic Solvent, Color Vision, Occupational Exposure
Funding: This study was supported by Iran Univrsity of Medical Sciences.
Conflict of interest: None declared.
Ethical approval: The Ethics Committee of Iran Univrsity of Medical Sciences, approved the study.
Type of Study: Research |
Subject:
طب كار
Received: 2020/05/13 | Accepted: 2020/05/13 | Published: 2020/05/13
Received: 2020/05/13 | Accepted: 2020/05/13 | Published: 2020/05/13
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