Volume 23, Issue 8 (1-2025)                   JRUMS 2025, 23(8): 738-745 | Back to browse issues page

Ethics code: IR.RUMS.REC.1400.103


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Karimifard M, Monamian A, Kamiab Z, Shafiepour M S. Study of the Correlation between Lipid Profile and Vitamin D Level in Patients Referred to Rafsanjan Salamat Clinic in 2021: A Short Report. JRUMS 2025; 23 (8) :738-745
URL: http://journal.rums.ac.ir/article-1-7344-en.html
Abstract:   (578 Views)
Background and Objectives: The aim of this study was to investigate the relationship between vitamin D status and serum lipids in patients referred to Rafsanjan Salamat Clinic in 2021.
Materials and Methods: In this descriptive study, 112 people were investigated. After ten hours of fasting, serum levels of vitamin D, cholesterol, LDL, HDL, and triglyceride were measured. Data were analyzed using one-way analysis of variance and Pearson’s correlation coefficient. 
Results: There was a significant association between serum levels of vitamin D  and more favorable LDL, cholesterol, and HDL levels (p<0.05). In obese individuals, high levels of this vitamin were associated only with higher HDL levels. In vitamin D consumers, blood cholesterol level was significantly lower (p<0.05), but vitamin D supplementation did not show a statistically significant association with LDL and triglyceride levels (p=0.0456).
Conclusion: Blood levels of vitamin D are associated with more favorable levels of LDL and HDL and cholesterol, especially in women. More studies are suggested to investigate this relationship.
Keywords: Vitamin D, Lipid, Cholesterol, Triglyceride, Low-density lipoprotein, High-density lipoprotein
Funding: This study did not have any funds. 
Conflict of interest: None declared. 
Ethical Considerations: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study (IR.RUMS: REC.1397.073).
Authors’ Contributions:
- Conceptualization: Maryam Karimifard
- Methodology: Maryam Karimifard
- Data collection: Anise Monamian
- Formal analysis: Zahra Kamiab
- Supervision: Maryam Karimifard
- Project administration: Maryam Karimifard
- Writing – original draft: Mohammadreza Shafiepour, Anise Monamian
 
Citation: Karimifard M, Monamian A, Kamiab Z, Shafiepour MR. Study of the Correlation Between Lipid Profile and Vitamin D Level in Patients Referred to Rafsanjan Salamat Clinic in 2021: A Short Report. J Rafsanjan Univ Med Sci 2024; 23 (8): 738-45. [Farsi]
- Writing – review & editing: Maryam Karimifard
Full-Text [PDF 697 kb]   (178 Downloads) |   |   Full-Text (HTML)  (237 Views)  
Type of Study: Research | Subject: Internal Medicine
Received: 2024/04/1 | Accepted: 2024/12/29 | Published: 2025/01/21

References
1. Christakos S, Ajibade DV, Dhawan P, Fechner AJ, Mady LJ. Vitamin D: metabolism. Rheumatic Disease Clinics 2012; 38 (1): 1-1.
2. Lehmann B, Meurer M. Vitamin D metabolism. Dermatologic Therapy 2010; (1): 2-12.
3. Colotta F, Jansson B, Bonelli F. Modulation of inflammatory and immune responses by vitamin D. Journal of Autoimmunity 2017; 85: 78-97.
4. Murdaca G, Tonacci A, Negrini S, Greco M, Borro M, Puppo F, et al. Emerging role of vitamin D in autoimmune diseases: An update on evidence and therapeutic implications. Autoimmunity Reviews 2019; 18 (9): 102350.
5. ‌Nordestgaard BG. A test in context: lipid profile, fasting versus non fasting. JACC 2017; 70 (13): 1637-46.
6. Jiang X, Peng M, Chen S, Wu S, Zhang W. Vitamin D deficiency is associated with dyslipidemia: a cross-sectional study in 3788 subjects. Current Medical Research and Opinion 2019 ;35 (6): 1059-63.
7. Nordestgaard BG. A test in context: lipid profile, fasting versus non fasting. JACC 2017; 70 (13): 1637-46.
8. Nouri Saeidlou S, Vahabzadeh D, Babaei F, Vahabzadeh Z. Seasonal variations of vitamin D and its relation to lipid profile in Iranian children and adults. JHPN 2017; 36 (1): 1-7. [Farsi].
9. Alloubani A, Nimer R, Samara R. Relationship between hyperlipidemia, cardiovascular disease and stroke: a systematic review. Current Cardiology Reviews 2021; 17 (6): 52-66.
10. Nakhl S, Sleilaty G, El Samad S, Saliba Y, Chahine R, Fares N. Association between vitamin D deficiency and lipid and non-lipid markers of cardiovascular diseases in the middle east region. EJCN 2019;73 (6): 850-8.
11. Jorde R, Grimnes G. Vitamin D and metabolic health with special reference to the effect of vitamin D on serum lipids. Progress in Lipid Research 2011; 50 (4): 303-12.
12. Kim MR, Jeong SJ. Relationship between vitamin D level and lipid profile in non-obese children. Metabolites 2019; 9 (7): 125.
13. Elshebiny A, AlHewishel MA, Al Ghadeer HA, Alosaif N, Al Furaikh BF, ALHejji MS, et al. Correlation of 25-Hydroxyvitamin D and Serum Lipid Levels Among Patients With Type 2 Diabetes. Cureus 2021; 13 (11).
14. Jafari T, Fallah AA, Barani A. Effects of vitamin D on serum lipid profile in patients with type 2 diabetes: a meta-analysis of randomized controlled trials. Clinical Nutrition 2016; 35(6): 1259-68. [Farsi].
15. Wang H, Xia N, Yang Y, Peng D-Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids in Health and Disease 2012; 11: 1-9.
16.  

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