Volume 19, Issue 1 (4-2020)
JRUMS 2020, 19(1): 81-96 |
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Kaeidi A, Rahmani M, Hassanshahi J. The Protective Effect of Carvacrol and Thymol as Main Polyphenolic Compounds of Thyme on Some Biologic Systems in Disease Condition:
A Narrative Review. JRUMS 2020; 19 (1) :81-96
URL: http://journal.rums.ac.ir/article-1-5045-en.html
URL: http://journal.rums.ac.ir/article-1-5045-en.html
Rafsanjan University of Medical Sciences
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The Protective Effect of Carvacrol and Thymol as Main Polyphenolic Compounds of Thyme on Some Biologic Systems in Disease Condition:
A Narrative Review
A. Kaeidi[1], M. R. Rahmani[2], J. Hassanshahi[3]
Received: 19/11/2019 Sent for Revision: 17/12/2019 Received Revised Manuscript: 11/01/2020 Accepted: 15/01/2020
Thyme plant is a member of the mint family that is considered as an aromatic perennial evergreen medical herb. Carvacrol and thymol are known as two important phenolic compounds of thyme plant. Carvacrol and thymol have been identified as antioxidant, anti-oxidative and anti-inflammatory substances. Also, the neuroprotective, hepatoprotective and renoprotective effects of these polyphenolic compounds have been identified in various diseases. In addition, carvacrol inhibits platelet aggregation and is capable to modulate the signaling pathways involved in inflammation and cellular proliferation. The protective effects of carvacrol and thymol have also been reported in some body systems including the respiratory, gastrointestinal, and endocrine systems. In the present review study, the protective role of carvacrol and thymol as the main compounds of thymus plant has been studied on different biologic systems in disease models.
Key words: Thymus, Carvacrol, Thymol, Antioxidant, Protective effect
Funding: None declared.
Conflict of interest: All of the authors declared no conflict of interest.
Ethical approval: None declared
How to cite this article: Kaeidi A, Rahmani M R, Hassanshahi J. The Protective Effect of Carvacrol and Thymol as Main Polyphenolic Compounds of Thyme on Some Biologic Systems in Disease Condition: A Narrative Review. J Rafsanjan Univ Med Sci 2020; 19 (1): 81-96. [Farsi]
[1]- Assistant Prof., Physiology-Pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran, ORCID: 0000-0002-3292-2603
Dept. of Physiology and Pharmacology, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
A Narrative Review
A. Kaeidi[1], M. R. Rahmani[2], J. Hassanshahi[3]
Received: 19/11/2019 Sent for Revision: 17/12/2019 Received Revised Manuscript: 11/01/2020 Accepted: 15/01/2020
Thyme plant is a member of the mint family that is considered as an aromatic perennial evergreen medical herb. Carvacrol and thymol are known as two important phenolic compounds of thyme plant. Carvacrol and thymol have been identified as antioxidant, anti-oxidative and anti-inflammatory substances. Also, the neuroprotective, hepatoprotective and renoprotective effects of these polyphenolic compounds have been identified in various diseases. In addition, carvacrol inhibits platelet aggregation and is capable to modulate the signaling pathways involved in inflammation and cellular proliferation. The protective effects of carvacrol and thymol have also been reported in some body systems including the respiratory, gastrointestinal, and endocrine systems. In the present review study, the protective role of carvacrol and thymol as the main compounds of thymus plant has been studied on different biologic systems in disease models.
Key words: Thymus, Carvacrol, Thymol, Antioxidant, Protective effect
Funding: None declared.
Conflict of interest: All of the authors declared no conflict of interest.
Ethical approval: None declared
How to cite this article: Kaeidi A, Rahmani M R, Hassanshahi J. The Protective Effect of Carvacrol and Thymol as Main Polyphenolic Compounds of Thyme on Some Biologic Systems in Disease Condition: A Narrative Review. J Rafsanjan Univ Med Sci 2020; 19 (1): 81-96. [Farsi]
Dept. of Physiology and Pharmacology, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
[2]- Assistant Prof., Physiology-Pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran, ORCID: 0000-0001-7395-5770
[3]- Assistant Prof., Dept. of Physiology and Pharmacology, Rafsanjan University of Medical Sciences, Rafsanjan, Iran,ORCID: 0000-0003-3754-8152
(Corresponding Author) Tel: (034) 31315083, Fax: (034) 31315003, E-mail: hasanshahij@rums.ac.ir
(Corresponding Author) Tel: (034) 31315083, Fax: (034) 31315003, E-mail: hasanshahij@rums.ac.ir
Type of Study: Review Article |
Subject:
Physiology
Received: 2019/11/15 | Accepted: 2020/01/15 | Published: 2020/04/22
Received: 2019/11/15 | Accepted: 2020/01/15 | Published: 2020/04/22
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