Journal of Rafsanjan University of Medical Sciences

  Background and Objective : Lymphovascular involvement is the main and most important prognostic factor in colorectal cancer. This study aimed to evaluate the relationship of morphological differentiation and lymph/vascular involvement.

  Materials and Methods: In this cross-sectional study, the pathological results of 52 colectomy patients between 2006 and 2011 in Emam-Reza and Be’sat Hospital in Tehran with pathological confirmed colorectal cancers were analyzed. The X² test was used to compare discrete variables. The findings are presented as a frequency, percentage, mean and standard deviation.

  Results : There was no association between morphological differentiation and lymph node involvement
(p= 0.936) as well as involvement of peripheral lymph nodes (p= 0.365). While the degree of morphological differentiation was significantly associated with vascular involvement (p= 0.031) and distant metastases
(p= 0.031).

  Conclusion: Morphological differentiation of the tumor can predict vascular involvement and distant metastasis in colorectal carcinoma patients, although the association was not observed with the lymph nodes involvement.

  Key words: Colorectal carcinoma, Morphological differentiation, Vascular involvement, Lymph nodes

  Funding: This research was funded by AJA University of Medical Sciences.

  Conflict of interest: None declared.

  Etical approval: The Ethics Committee of AJA University of Medical Sciences approved the study.

 How to cite this article : Ziari K , Gohari Moghaddam K, Alizadeh K, Dadpay M . The Relationship between Morphological Differentiation of Colorectal Cancer with Lymph/Vascular Involvement: A Short Report . J Rafsanjan Univ Med Sci 2014 12(11): 943-8. [Farsi]