Volume 23, Issue 2 (6-2024)
JRUMS 2024, 23(2): 157-168 |
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Ethics code: IR.RUMS.REC.1401.075
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Barzegar M, Salmei S, kamiab Z. Neonatal and Maternal Outcomes Before and After COVID-19 Pandemic:
A Cross-Sectional Study. JRUMS 2024; 23 (2) :157-168
URL: http://journal.rums.ac.ir/article-1-7337-en.html
URL: http://journal.rums.ac.ir/article-1-7337-en.html
Rafsanjan University of Medical Sciences
Abstract: (54 Views)
Background and Objectives: Coronavirus disease increased concern about vulnerable groups of society including pregnant women and babies. This study was conducted in order to investigate maternal and neonatal outcomes in newborns admitted to Ali Ibn Abi Talib Hospital in Rafsanjan before and after the COVID-19 pandemic.
Materials and Methods: In this cross-sectional study, 337 infants admitted to the hospital in the first 3 months of 2019 (before the start of the COVID-19 pandemic) and 194 infants admitted in the first 3 months of 2020 (after the start of the COVID-19 pandemic) were included. Demographic characteristics and maternal and neonatal complications were extracted from the files and analyzed by independent two-sample t-test and chi-square test.
Results: The Apgar scores of the first and fifth minutes had significantly decreased during the COVID-19 pandemic (p<0.001), while infant death (p=0.003) and asphyxia at birth (p<0.001) had significantly increased. The frequency of premature rupture of fetal membranes, pre-eclampsia, eclampsia, and diabetes in the pregnant mothers before and after the pandemic were not statistically significant (p>0.05).
Conclusion: According to the results of the present study, although there was no difference in the prevalence of maternal outcomes between the period of COVID-19 and before, but the outcomes of newborns during the period of COVID-19 were more than before, which indicates the need for more careful prenatal care, health protocols training, and careful monitoring of the fetus during and after delivery to reduce neonatal complications and outcomes during the COVID-19.
Keywords: Maternal outcomes, Neonatal outcomes, COVID-19 pandemic
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical considerations: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study (IR.RUMS.REC.1401.075).
Authors’ contributions:
- Conceptualization: Sedigheh Salmeei
- Methodology: Mina Barzegar
- Data collection: Mina Barzegar
- Formal analysis: Zahra Kamiab, Mina Barzegar
- Supervision: Sedigheh Salmeei, Zahra Kamiab
- Project administration: Sedigheh Salmeei
- Writing - original draft: Mina Barzegar
- Writing - review and editing: Mina Barzegar, Sedigheh Salmeei, Zahra Kamiab
Materials and Methods: In this cross-sectional study, 337 infants admitted to the hospital in the first 3 months of 2019 (before the start of the COVID-19 pandemic) and 194 infants admitted in the first 3 months of 2020 (after the start of the COVID-19 pandemic) were included. Demographic characteristics and maternal and neonatal complications were extracted from the files and analyzed by independent two-sample t-test and chi-square test.
Results: The Apgar scores of the first and fifth minutes had significantly decreased during the COVID-19 pandemic (p<0.001), while infant death (p=0.003) and asphyxia at birth (p<0.001) had significantly increased. The frequency of premature rupture of fetal membranes, pre-eclampsia, eclampsia, and diabetes in the pregnant mothers before and after the pandemic were not statistically significant (p>0.05).
Conclusion: According to the results of the present study, although there was no difference in the prevalence of maternal outcomes between the period of COVID-19 and before, but the outcomes of newborns during the period of COVID-19 were more than before, which indicates the need for more careful prenatal care, health protocols training, and careful monitoring of the fetus during and after delivery to reduce neonatal complications and outcomes during the COVID-19.
Keywords: Maternal outcomes, Neonatal outcomes, COVID-19 pandemic
Funding: This study did not have any funds.
Conflict of interest: None declared.
Ethical considerations: The Ethics Committee of Rafsanjan University of Medical Sciences approved the study (IR.RUMS.REC.1401.075).
Authors’ contributions:
- Conceptualization: Sedigheh Salmeei
- Methodology: Mina Barzegar
- Data collection: Mina Barzegar
- Formal analysis: Zahra Kamiab, Mina Barzegar
- Supervision: Sedigheh Salmeei, Zahra Kamiab
- Project administration: Sedigheh Salmeei
- Writing - original draft: Mina Barzegar
- Writing - review and editing: Mina Barzegar, Sedigheh Salmeei, Zahra Kamiab
Type of Study: Description |
Subject:
Pediatrics
Received: 2024/03/20 | Accepted: 2024/06/21 | Published: 2024/06/21
Received: 2024/03/20 | Accepted: 2024/06/21 | Published: 2024/06/21
References
1. Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents 2020; 55(3): 105924.
2. Pal M, Berhanu G, Desalegn C, Kandi V. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): an update. Cureus 2020; 12(3).
3. Sharma A, Tiwari S, Deb MK, Marty JL. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies. Int J Antimicrob Agents 2020; 56(2): 106054.
4. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The lancet 2020; 395(10229): 1054-62.
5. Parvaz N, Amin F, Nadimi AE, Eslami H. Correlation between weather conditions and COVID-19 pandemic in the southeast area of Iran. Spat Inf Res 2020; 31(6): 685-93.
6. Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know. Am J Obste Gynecol 2020; 222(5): 415-26.
7. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 2020; 382(10): 970-1.
8. Shariatzadeh M, Sarfaraz Z, Alazemani NF, Azizi HR, Ahmadi Y. The effect of COVI-19 on the health status of pregnant women and their neonates: A systematic review study. IJNV 2020; 9(1). [Farsi]
9. Schwartz DA, Graham AL. Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020; 12(2): 194.
10. Abedzadeh-Kalahroudi M, Karimian Z, Nasiri S, Khorshidifard MS. Anxiety and perceived stress of pregnant women towards COVID-19 disease and its related factors in Kashan (2020). Iran J Obstet Gynecol Infertil 2021; 24(5): 8-18. [Farsi]
11. Irani M, Pakfetrat A, Mask MK. Novel coronavirus disease 2019 and perinatal outcomes. J Educ Health Promot 2020; 9(1): 78.
12. Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol 2020; 223(1): 111.e1-111.e14.
13. Moaya M, Shahali S, Farhoudi B. Maternal and neonatal outcomes of pregnant women with COVID-19 in Amir-al-momenin hospital during March to May 2020. Iran J Obstet Gynecol Infertil 2020; 23(9): 35-42. [Farsi]
14. Palatnik A, McIntosh JJ. Protecting labor and delivery personnel from COVID-19 during the second stage of labor. Am J Perinatol 2020; 37(08): 854-6.
15. Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, et al. Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 infection: the INTERCOVID multinational cohort study. JAMA Pediatr 2021; 175(8): 817-26.
16. Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal outcomes of pregnant women with coronavirus disease 2019 (COVID-19) pneumonia: a case-control study. Clin Infect Dis 2020; 71(16): 2035-41.
17. Casanova R, Goepfert AR, Hueppchen N, Weiss PM, Connolly AM. Beckmann and Ling's obstetrics and gynecology. 9th Edition, United State of America, Lippincott Williams & Wilkins 2023; pp 576.
18. Mohagheghi P. Textbook of Neonatal Respiratory Care. Tehran, Fan o Honar Advertising & Publishing 2016; pp 224. [Farsi]
19. Martin RJ, Fanaroff AA. Fanaroff and Martin's Neonatal-Perinatal Medicine. 11th Edition, Netherlands, Elsevier 2024; 2322.
20. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The lancet 2020; 395(10226): 809-15.
21. Azh N, Pakniat H, Rajabi M, Ranjkesh F. Evaluation of Pregnancy Outcomes in Pregnant Women with COVID-19 in Qazvin 1399. Iran J Epidemiol 2021; 16(5): 10-9.
22. Askary E, Poordast T, Shiravani Z, Ali MA, Hashemi A, Naseri R, et al. Coronavirus disease 2019 (COVID-19) manifestations during pregnancy in all three trimesters: A case series. Int J Reprod Med 2021; 19(2): 191.
23. Esmailpour ER, Borghei NS, Mehrbakhsh Z, Rahimian S. Clinical signs and maternal and neonatal outcomes of pregnant women with COVID-19 hospitalized in the first and second wave of coronavirus in Golestan province. Iran J Obstet Gynecol Infertil 2022; 25.
24. Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, Abascal-Saiz A, et al. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Sci Rep 2021; 11(1): 13898.
25. Khoury R, Bernstein PS, Debolt C, Stone J, Sutton DM, Simpson LL, et al. Characteristics and outcomes of 241 births to women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at five New York City medical centers. Obstet Gynecol 2020; 136(2): 273-82.
26. Zlochiver V, Tilkens B, Moreno ACP, Aziz F, Jan MF. COVID-19 deliveries: maternal features and neonatal outcomes. J Patient Cent Res Rev 2021; 8(3): 286.
27. Khan S, Jun L, Siddique R, Li Y, Han G, Xue M, et al. Association of COVID-19 with pregnancy outcomes in health-care workers and general women. Clin Microbiol Infect 2020; 26(6): 788-90.
28. Garcia-Ruiz I, Sulleiro E, Serrano B, Fernandez-Buhigas I, Rodriguez-Gomez L, Fernandez DS-N, et al. Congenital infection of SARS-CoV-2 in live-born neonates: a population-based descriptive study. Clin Microbiol Infect 2021; 27(10): 1521.e1-1521.e5
29. Liu W, Wang Q, Zhang Q, Chen L, Chen J, Zhang B, et al. Coronavirus disease 2019 (COVID-19) during pregnancy: A case series. Preprints 2020; 2020020373.
30. Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis 2020; 20(5): 559-64.
31. Elshafeey F, Magdi R, Hindi N, Elshebiny M, Farrag N, Mahdy S, et al. A systematic scoping review of COVID‐19 during pregnancy and childbirth. Int J Gynaecol Obstet 2020; 150(1): 47-52. [Farsi]
32. Knight M, Bunch K, Vousden N, Morris E, Simpson N, Gale C, et al. Characteristics and outcomes of pregnant women hospitalised with confirmed SARS-CoV-2 infection in the UK: a national cohort study using the UK Obstetric Surveillance System (UKOSS). Medrxiv 2020: 2020-5.
33. Wei SQ, Bilodeau-Bertrand M, Liu S, Auger N. The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis. CMAJ 2021; 193(16): E540-E8.
34. Papapanou M, Papaioannou M, Petta A, Routsi E, Farmaki M, Vlahos N, et al. Maternal and neonatal characteristics and outcomes of COVID-19 in pregnancy: an overview of systematic reviews. Int J Environ Res Public Health 2021; 18(2): 596.
35. Akbarzadeh H, Saadati Rad MT, Ebrahimi M, Sina S, Ghabimi M. Coronavirus disease 2019 (COVID-19), perinatal and neonatal outcomes: A systematic review study. Nursing and Midwifery J 2021; 18(10): 785-94. [Farsi]
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