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جلد 24 شماره 1 صفحات 103-80 |
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Soluki M, Taghizadeh Momen L, Mahmoudi F, Abdolmaleki A. The Influence of Gender on Diseases of the Nervous System: A Narrative Review. JRUMS 2025; 24 (1) :80-103
URL: http://journal.rums.ac.ir/article-1-7571-fa.html
URL: http://journal.rums.ac.ir/article-1-7571-fa.html
سلوکی میلاد، تقی زاده مومن لیلا، محمودی فریبا، عبدالملکی آرش. تأثیر جنسیت در بیماریهای دستگاه عصبی: یک مرور روایی. مجله دانشگاه علوم پزشکی رفسنجان. 1404; 24 (1) :80-103
دانشگاه محقق اردبیلی
چکیده: (304 مشاهده)
بیماریهای دستگاه عصبی، علاوه بر محدودیتهای ایجاد کرده برای فرد بیمار، هزینههای اقتصادی و اجتماعی زیادی را به بار می‌آورند. علی رغم تلاش بسیار در جهت درمان این آسیبها، همچنان بهبود و بازیابی کامل بیماران چالش برانگیز است. به‌دنبال اختلالات عصبی، مجموعهای از وقایع نظیر التهاب، افزایش استرس اکسیداتیو و گسترش آسیب رخ می‌دهد که می‌تواند سبب آسیب به میتوکندری نورون ها، تخریب پروتئینها و آپوپتوز سلولی شود. بررسی نقش جنسیت، به عنوان یک متغیر بیولوژیکی، در مطالعات تحقیقاتی از اهمیت بالایی برخوردار است. توسعه درمان‌های وابسته به جنس ممکن است توانایی ما را برای درمان بیماریهای دستگاه عصبی بهبود بخشد. بنابراین هدف از این مطالعه‌ی مروری، تعیین نقش جنسیت در بیماریهای دستگاه عصبی است.
در مطالعه مروری حاضر، مقالات چاپ شده در پایگاه‌های علمی Google Scholar، PubMed، Scopus و Science Direct با توجه به کلید واژه‌های مختلفی از جمله جنسیت، بیماریهای دستگاه عصبی، هورمون‌های جنسی و تفاوت‌های جنسیتی در بروز و درمان بیماریهای نوروژنراتیو، مورد بررسی و تحلیل قرار گرفتند. تفاوت‌های جنسیتی منجر به ایجاد تفاوت در عملکرد و پاسخ‌دهی به محرک‌ها در سیستم عصبی می‌شود. در نتیجه در بیماریهای مختلف دستگاه عصبی شیوع و علائم بیماری، میزان و سرعت پاسخ‌دهی به درمان در مردان و زنان می‌تواند متفاوت باشد. در این مقاله، به نقش جنسیت به عنوان نوعی متغیر بیولوژیکی در بیماریهای دستگاه عصبی تأکید شده است. مقایسه جنسیت‌ها می‌تواند زمینه را برای توسعهی پزشکی شخصی و روش‌های درمانی در ضایعات دستگاه عصبی، بسیار هموار گرداند.
واژه‌های کلیدی: جنسیت، بیماریهای نورودژنراتیو، هورمون‌های جنسی، دستگاه عصبی
در مطالعه مروری حاضر، مقالات چاپ شده در پایگاه‌های علمی Google Scholar، PubMed، Scopus و Science Direct با توجه به کلید واژه‌های مختلفی از جمله جنسیت، بیماریهای دستگاه عصبی، هورمون‌های جنسی و تفاوت‌های جنسیتی در بروز و درمان بیماریهای نوروژنراتیو، مورد بررسی و تحلیل قرار گرفتند. تفاوت‌های جنسیتی منجر به ایجاد تفاوت در عملکرد و پاسخ‌دهی به محرک‌ها در سیستم عصبی می‌شود. در نتیجه در بیماریهای مختلف دستگاه عصبی شیوع و علائم بیماری، میزان و سرعت پاسخ‌دهی به درمان در مردان و زنان می‌تواند متفاوت باشد. در این مقاله، به نقش جنسیت به عنوان نوعی متغیر بیولوژیکی در بیماریهای دستگاه عصبی تأکید شده است. مقایسه جنسیت‌ها می‌تواند زمینه را برای توسعهی پزشکی شخصی و روش‌های درمانی در ضایعات دستگاه عصبی، بسیار هموار گرداند.
واژه‌های کلیدی: جنسیت، بیماریهای نورودژنراتیو، هورمون‌های جنسی، دستگاه عصبی
نوع مطالعه: مقاله مروري |
موضوع مقاله:
زيست شناسي
دریافت: 1403/9/1 | پذیرش: 1403/12/4 | انتشار: 1404/2/1
دریافت: 1403/9/1 | پذیرش: 1403/12/4 | انتشار: 1404/2/1
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