Volume 24, Issue 8 (11-2025)
JRUMS 2025, 24(8): 759-766 |
Back to browse issues page
Ethics code: IR
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Shakarami A H, Fazaeli A. A Rare Case Report of Brachial Artery Involvement and Subclavian Artery Occlusion in a Patient with Takayasu Arteritis. JRUMS 2025; 24 (8) :759-766
URL: http://journal.rums.ac.ir/article-1-7754-en.html
URL: http://journal.rums.ac.ir/article-1-7754-en.html
medical science of Hamedan
Abstract: (23 Views)
Background and Objectives: Takayasu arteritis is a rare systemic vasculitis, and involvement of the brachial artery can be considered an unusual finding.
Case Report: A 25-year-old female athlete with no remarkable past medical history presented with interscapular pain, paresthesia, and weakness of the left upper limb. Physical examination revealed absent pulse and unrecordable blood pressure in the left arm. The erythrocyte sedimentation rate (ESR) was elevated at 95 mm/hour. Computed tomography angiography demonstrated complete occlusion of the left subclavian artery along with the uncommon involvement of the brachial artery. According to the diagnostic criteria, Type I Takayasu arteritis was confirmed.
Conclusion: Due to the patient’s young age and fertility considerations, treatment was initiated with methylprednisolone pulse therapy, followed by a maintenance regimen of mycophenolate mofetil and prednisolone. After four weeks, the patient’s clinical symptoms improved, although the pulse in the affected limb remained impalpable. This case highlights the importance of considering rheumatologic diseases such as Takayasu arteritis in young women presenting with atypical musculoskeletal or vascular symptoms, as well as the necessity of timely treatment to prevent permanent complications.
Keywords: Takayasu arteritis, Brachial artery, Subclavian artery
Conflict of Interest: None declared.
Funding: This research received no specific grant from any funding agency.
Ethical considerations: This report was prepared to advance medical knowledge and share a valuable educational case. Respect for patient privacy, human dignity, and confidentiality formed the foundation throughout all stages of writing and publication. The authors acknowledge that due to the retrospective nature of case reports (often compiled post-treatment without prior publication plans), obtaining a formal ethics code before drafting was not feasible. Nevertheless, our commitment to upholding the highest ethical standards in protecting patient privacy remains fundamental and non-negotiable.
Author’s contributions:
Conceptualization: Alireza Fazaeli
Methodology: Amirhossein Shakarmi
Data collection: Amirhossein Shakarmi
Formal analysis: Alireza Fazaeli
Supervision: Alireza Fazaeli
Project administration: Alireza Fazaeli
Writing – original draft: Amirhossein Shakarmi
Writing – review & editing: Amirhossein Shakarmi
Case Report: A 25-year-old female athlete with no remarkable past medical history presented with interscapular pain, paresthesia, and weakness of the left upper limb. Physical examination revealed absent pulse and unrecordable blood pressure in the left arm. The erythrocyte sedimentation rate (ESR) was elevated at 95 mm/hour. Computed tomography angiography demonstrated complete occlusion of the left subclavian artery along with the uncommon involvement of the brachial artery. According to the diagnostic criteria, Type I Takayasu arteritis was confirmed.
Conclusion: Due to the patient’s young age and fertility considerations, treatment was initiated with methylprednisolone pulse therapy, followed by a maintenance regimen of mycophenolate mofetil and prednisolone. After four weeks, the patient’s clinical symptoms improved, although the pulse in the affected limb remained impalpable. This case highlights the importance of considering rheumatologic diseases such as Takayasu arteritis in young women presenting with atypical musculoskeletal or vascular symptoms, as well as the necessity of timely treatment to prevent permanent complications.
Keywords: Takayasu arteritis, Brachial artery, Subclavian artery
Conflict of Interest: None declared.
Funding: This research received no specific grant from any funding agency.
Ethical considerations: This report was prepared to advance medical knowledge and share a valuable educational case. Respect for patient privacy, human dignity, and confidentiality formed the foundation throughout all stages of writing and publication. The authors acknowledge that due to the retrospective nature of case reports (often compiled post-treatment without prior publication plans), obtaining a formal ethics code before drafting was not feasible. Nevertheless, our commitment to upholding the highest ethical standards in protecting patient privacy remains fundamental and non-negotiable.
Author’s contributions:
Conceptualization: Alireza Fazaeli
Methodology: Amirhossein Shakarmi
Data collection: Amirhossein Shakarmi
Formal analysis: Alireza Fazaeli
Supervision: Alireza Fazaeli
Project administration: Alireza Fazaeli
Writing – original draft: Amirhossein Shakarmi
Writing – review & editing: Amirhossein Shakarmi
|
Citation: Shakarami AH, Fazaeli AR. A Rare Case Report of Brachial Artery Involvement and Subclavian Artery Occlusion in a Patient with Takayasu Arteritis. J Rafsanjan Univ Med Sci 2025; 24 (8): 759-66. [Farsi]
|
Type of Study: Case Report |
Subject:
Romathology
Received: 2025/06/1 | Accepted: 2025/10/8 | Published: 2025/11/19
Received: 2025/06/1 | Accepted: 2025/10/8 | Published: 2025/11/19
References
1. Hileeyesus S, Tadesse A, Fekrie A, Shetie B, Bekele N, Beyazn G, et al. Takayasu arteritis: Diagnosis of a rare clinical entity: A case report. Medicine (Baltimore) 2025; 104(14): e42096.
2. Danda D, Manikuppam P, Tian X, Harigai M. Advances in Takayasu arteritis: An Asia Pacific perspective. Front Med (Lausanne) 2022; 9: 952972.
3. Trinidad B, Surmachevska N, Lala V. Takayasu Arteritis. StatPearls [Internet]. 2025.
4. Numano F. The story of Takayasu arteritis. Rheumatology (Oxford) 2002; 41(1): 103-6.
5. Roberts J, Monteagudo L, Shah P, Stitt R. Takayasu Arteritis Clinical Presentation2024 October 29. Available from: https://emedicine.medscape.com/article/332378-clinical.
6. Watanabe Y, Miyata T, Tanemoto K. Current Clinical Features of New Patients With Takayasu Arteritis Observed From Cross-Country Research in Japan. Circulation 2015; 132(18): 1701-9.
7. Miyamoto S, Wu H, Kubo T, Kawaguchi K, Ide T, Takemura N, et al. Single stage multiple stenting in Takayasu's arteritis. Case report. Neurol Med Chir (Tokyo). 2012; 52(4): 219-23.
8. Kancherla H, Konduri G, Bollam A, Atla K, Injeti N. Takayasu arteritis: A case report. Journal of Young Pharmacists 2022; 14(1): 130-2.
9. Emam MM, Abiyarghamsari M, Kazempour M, Haghighi-Morad M, Farsad F. Multiple sclerosis in a patient with Takayasu's Arteritis: A case report. Caspian J Intern Med 2024; 15(4): 729-34.
10. Choi HY, Lee S, Park J, Song YJ, Kim DK, Kim KH, et al. Endovascular treatment of Takayasu arteritis in a middle-aged woman with syncope and limb claudication: a case report. Journal of Yeungnam Medical Science 2023; 40(4): 448-53.
11. Rahman SSu, Shehri AA, Ghamdi MA, Shareef MA. Stroke and Renal Artery Stenosis from Takayasu's Arteritis Diagnosed in a 57-Year-Old Male Patient. Saudi Journal of Kidney Diseases and Transplantation. 2019; 30(3): 710-4.
12. Gardner JD, Lee KR, Abdou NI. Takayasu's arteritis: reversal of pulse deficit after early treatment with corticosteroids. J Rheumatol 1984; 11(1): 92-3.
13. Kumar A, Hussain I, Joshi D, Singh VK. Syncopal Seizure: A Rare Manifestation of Takayasu Arteritis. Neurology India 2025; 73(2): 371-3.
14. Leigh MB, Kor S, Czantrak P, Sacirovic M, Pagonas N, Hillmeister P, et al. Recanalization of bilateral axillaris/brachialis artery occlusion in a patient with Takayashu arteritis: First case report on using a novel drug-coated nitinol "chocolate" balloon catheter. Clin Case Rep 2018; 6(12): 2490-4.
15. Hedna VS, Patel A, Bidari S, Elder M, Hoh BL, Yachnis A, et al. Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review. Surg Neurol Int 2012; 3: 132.
16. Schmidt WA, Schäfer VS. Diagnosing vasculitis with ultrasound: findings and pitfalls. Therapeutic Advances in Musculoskeletal Disease. 2024; 16:1759720X241251742.
17. Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol 2002; 55(7): 481-6.
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
