Volume 11, Issue 3 (7-2012)                   JRUMS 2012, 11(3): 197-206 | Back to browse issues page

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Chemical Assessment of Active Ingredients and Anti-oxidant Effects of Trachyspermum Copticum's Seeds harvested in Yazd Province. JRUMS. 2012; 11 (3) :197-206
URL: http://journal.rums.ac.ir/article-1-5317-en.html
Abstract:   (1608 Views)
Background and Objectives: rachyspermum copticum as a medicinal plant has many therapeutic properties including; anti-flatulence,  anti-emesis, anti- rheumatism and expectorant. The goal of this study was to identify the active ingredients and anti-oxidant effects of Trachyspermum Copticum's seeds harvested in Yazd province.
Materials and Methods: The essence of the seeds was first extracted by Clevenger apparatus. The active components of the essence were then separated and identified by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) methods. The anti-oxidant effect was determined  by DPPH (2, 2-diphenyl-1-picrylhydrazyl ) test as  the half maximal inhibitory concentration (IC50) and the total amount of phenolic components of the essence was quantified utilising the Follin-Ciocalteu method.
Results: The results of this study revealed that thymol (64.9%) and γ-Terpinene (11.1%)  were the most prevalent components of the essence. Also, the anti-oxidant activity and the total amount of phenolic component of the essence were 0.711µg/ml-1  and 162.62 mg/g-1 resepectively.
Conclusion: The result of this research indicated that the active ingrediebts of  native Trachyspermum copticum harvested in Yazd province were much higher than the ones found in Trachyspermum copticum harvested in other places.
Key words: Trachyspermum Copticum, Therapeutic Effects, Seed essence, Antioxidant, active ingrediernts
Funding: This research was founded by Shahid Sadoughi University of Medical sciences, Yazd and Shahid Beheshty University of Tehran.
Conflict of interest: None declared.
Ethical approval: There is no human patient sampling in this article.
How to cite this article: Haghiroalsadat BF, Vahidi AR, Azimzadeh M, Kalantar SM, Bernard F, Hokmollahi F. Chemical Assessment of Active Ingredients and Anti-oxidant Effects of Trachyspermum Copticum's Seeds harvested In Yazd Province. J Rafsanjan Univ Med Scie 2012; 11(3): 197-206. [Farsi]
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Type of Study: Research | Subject: Physiology
Received: 2020/05/10 | Accepted: 2020/05/10 | Published: 2020/05/10

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